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We consider learning parameters of Binomial Hidden Markov Models, which may be used to model DNA methylation data. The standard algorithm for the problem is EM, which is computationally expensive for sequences of the scale of the mammalian…

Machine Learning · Computer Science 2018-02-08 Chicheng Zhang , Eran A. Mukamel , Kamalika Chaudhuri

The convergence of expectation-maximization (EM)-based algorithms typically requires continuity of the likelihood function with respect to all the unknown parameters (optimization variables). The requirement is not met when parameters…

Signal Processing · Electrical Eng. & Systems 2024-04-18 Geethu Joseph

Consider the setting of constrained optimization, with some parameters unknown at solving time and requiring prediction from relevant features. Predict+Optimize is a recent framework for end-to-end training supervised learning models for…

Artificial Intelligence · Computer Science 2023-11-15 Xinyi Hu , Jasper C. H. Lee , Jimmy H. M. Lee

Expectation maximization (EM) is a technique for estimating maximum-likelihood parameters of a latent variable model given observed data by alternating between taking expectations of sufficient statistics, and maximizing the expected log…

Methodology · Statistics 2018-07-10 Donna Henderson , Gerton Lunter

Machine learning algorithms have been used widely in various applications and areas. To fit a machine learning model into different problems, its hyper-parameters must be tuned. Selecting the best hyper-parameter configuration for machine…

Machine Learning · Computer Science 2022-10-06 Li Yang , Abdallah Shami

We provide a general theory of the expectation-maximization (EM) algorithm for inferring high dimensional latent variable models. In particular, we make two contributions: (i) For parameter estimation, we propose a novel high dimensional EM…

Machine Learning · Statistics 2015-01-28 Zhaoran Wang , Quanquan Gu , Yang Ning , Han Liu

Herein, the Hidden Markov Model is expanded to allow for Markov chain observations. In particular, the observations are assumed to be a Markov chain whose one step transition probabilities depend upon the hidden Markov chain. An…

Machine Learning · Statistics 2023-04-18 Michael A. Kouritzin

Hidden Markov Models (HMM) model a sequence of observations that are dependent on a hidden (or latent) state that follow a Markov chain. These models are widely used in diverse fields including ecology, speech recognition, and…

Optimization and Control · Mathematics 2024-09-05 Sidonie Foulon , Thérèse Truong , Anne-Louise Leutenegger , Hervé Perdry

An algorithm used to extract HMM parameters is revisited. Most parts of the extraction process are taken from implemented Hidden Markov Toolkit (HTK) program under name HInit. The algorithm itself shows a few variations compared to another…

Sound · Computer Science 2019-08-09 Zulkarnaen Hatala , Victor Puturuhu

Bayesian networks (BN) are used in a big range of applications but they have one issue concerning parameter learning. In real application, training data are always incomplete or some nodes are hidden. To deal with this problem many learning…

Artificial Intelligence · Computer Science 2012-04-12 Fradj Ben Lamine , Karim Kalti , Mohamed Ali Mahjoub

In a hidden Markov model, the underlying Markov chain is usually hidden. Often, the maximum likelihood alignment (Viterbi alignment) is used as its estimate. Although having the biggest likelihood, the Viterbi alignment can behave very…

Methodology · Statistics 2013-07-31 Kristi Kuljus , Jüri Lember

Genetic fitness optimization using small populations or small population updates across generations generally suffers from randomly diverging evolutions. We propose a notion of highly probable fitness optimization through feasible…

Neural and Evolutionary Computing · Computer Science 2007-05-23 Paul Vitanyi

Factorial Hidden Markov Models (FHMMs) are powerful models for sequential data but they do not scale well with long sequences. We propose a scalable inference and learning algorithm for FHMMs that draws on ideas from the stochastic…

Machine Learning · Statistics 2016-10-31 Yin Cheng Ng , Pawel Chilinski , Ricardo Silva

Auto-encoding Variational Bayes (AEVB) is a powerful and general algorithm for fitting latent variable models (a promising direction for unsupervised learning), and is well-known for training the Variational Auto-Encoder (VAE). In this…

Machine Learning · Computer Science 2022-08-17 Yang Zhi-Han

We study a phase transition in parameter learning of Hidden Markov Models (HMMs). We do this by generating sequences of observed symbols from given discrete HMMs with uniformly distributed transition probabilities and a noise level encoded…

Statistical Mechanics · Physics 2021-10-13 Nikita Rau , Jörg Lücke , Alexander K. Hartmann

Mixture models are a fundamental tool in applied statistics and machine learning for treating data taken from multiple subpopulations. The current practice for estimating the parameters of such models relies on local search heuristics…

Machine Learning · Computer Science 2012-09-07 Animashree Anandkumar , Daniel Hsu , Sham M. Kakade

Large-scale machine learning (ML) models are increasingly being used in critical domains like education, lending, recruitment, healthcare, criminal justice, etc. However, the training, deployment, and utilization of these models demand…

Machine Learning · Computer Science 2025-03-31 Ding Zhu , Zhiqun Zuo , Mohammad Mahdi Khalili

The Mixture Transition Distribution (MTD) model was introduced by Raftery to face the need for parsimony in the modeling of high-order Markov chains in discrete time. The particularity of this model comes from the fact that the effect of…

Computation · Statistics 2008-12-18 Sophie Lèbre , Pierre-Yves Bourguinon

In this paper, a long-term survival model under competing risks is considered. The unobserved number of competing risks is assumed to follow a negative binomial distribution that can capture both over- and under-dispersion. Considering the…

Methodology · Statistics 2021-07-22 Suvra Pal

The Expectation--Maximization (EM) algorithm is a simple meta-algorithm that has been used for many years as a methodology for statistical inference when there are missing measurements in the observed data or when the data is composed of…

Machine Learning · Statistics 2022-11-15 Hideitsu Hino , Shotaro Akaho , Noboru Murata