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Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

We propose the Learned Primal-Dual algorithm for tomographic reconstruction. The algorithm accounts for a (possibly non-linear) forward operator in a deep neural network by unrolling a proximal primal-dual optimization method, but where the…

Optimization and Control · Mathematics 2018-07-06 Jonas Adler , Ozan Öktem

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Conventional breast cancer imaging techniques are nowadays based on the use of ionising radiations or ultrasound waves for the inspection of breast areas. Nevertheless, these conventional techniques present some drawbacks related to patient…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Michele Ambrosanio , Stefano Franceschini , Vito Pascazio , Fabio Baselice

Filtered back projection (FBP) is a commonly used technique in tomographic image reconstruction demonstrating acceptable quality. The classical direct implementations of this algorithm require the execution of $\Theta(N^3)$ operations,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-14 Anastasiya Dolmatova , Marina Chukalina , Dmitry Nikolaev

Photo-Acoustic Tomography (PAT) can reconstruct a distribution of optical absorbers acting as instantaneous sound sources in subcutaneous microvasculature of a human breast. Adjoint methods for PAT, typically Time-Reversal (TR) and…

Numerical Analysis · Mathematics 2018-06-25 Hongxiang Lin , Takashi Azuma , Mehmet Burcin Unlu , Shu Takagi

Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Huidong Xie , Hongming Shan , Wenxiang Cong , Chi Liu , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

In recent years, the integration of advanced imaging techniques and deep learning methods has significantly advanced computer-aided diagnosis (CAD) systems for breast cancer detection and classification. Transformers, which have shown great…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Mahtab Ranjbar , Mehdi Mohebbi , Mahdi Cherakhloo , Bijan Vosoughi. Vahdat

We propose a 3D neural network with specific loss functions for quantitative computed tomography (QCT) noise reduction to compute micro-structural parameters such as tissue mineral density (TMD) and bone volume ratio (BV/TV) with…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Felix Thomsen , José M. Fuertes García , Manuel Lucena , Juan Pisula , Rodrigo de Luis García , Jan Broggrefe , Claudio Delrieux

Statistical iterative reconstruction is expected to improve the image quality of megavoltage computed tomography (MVCT). However, one of the challenges of iterative reconstruction is its large computational cost. The purpose of this work is…

This paper introduces a novel method for reconstructing cone beam computed tomography (CBCT) images for arbitrary orbits using a differentiable shift-variant filtered backprojection (FBP) neural network. Traditional CBCT reconstruction…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Chengze Ye , Linda-Sophie Schneider , Yipeng Sun , Mareike Thies , Siyuan Mei , Andreas Maier

Data scarcity hinders deep learning for medical imaging. We propose a framework for breast cancer classification in thermograms that addresses this using a Diffusion Probabilistic Model (DPM) for data augmentation. Our DPM-based…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Sepehr Salem , M. Moein Esfahani , Jingyu Liu , Vince Calhoun

Optical projection tomography (OPT) is a powerful tool for biomedical studies. It achieves 3D visualization of mesoscopic biological samples with high spatial resolution using conventional tomographic-reconstruction algorithms. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Yan Liu , Jonathan Dong , Thanh-An Pham , Francois Marelli , Michael Unser

Here an image restoration on the basis of pixel simultaneous detection probabilities (PSDP) is proposed. These probabilities can be precisely determined by means of correlations measurement [NIMA 586 (2008) 314-326]. The proposed image…

Medical Physics · Physics 2009-09-29 V. Grabski

For reconstructing large tomographic datasets fast, filtered backprojection-type or Fourier-based algorithms are still the method of choice, as they have been for decades. These robust and computationally efficient algorithms have been…

Numerical Analysis · Mathematics 2021-08-31 Poulami Somanya Ganguly , Daniël M. Pelt , Doga Gürsoy , Francesco de Carlo , K. Joost Batenburg

Quantitative comparison of the quality of photoacoustic image reconstruction algorithms remains a major challenge. No-reference image quality measures are often inadequate, but full-reference measures require access to an ideal reference…

Proton computed tomography (pCT) is a novel medical imaging modality for mapping the distribution of proton relative stopping power (RSP) in medical objects of interest. Compared to conventional X-ray computed tomography, where range…

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Iterative image reconstruction algorithms for optoacoustic tomography (OAT), also known as photoacoustic tomography, have the ability to improve image quality over analytic algorithms due to their ability to incorporate accurate models of…

Analysis of PDEs · Mathematics 2015-06-05 Kun wang , Richard Su , Alexander A. Oraevsky , Mark A. Anastasio

The goal of this thesis is to provide a framework for the use of task-based metrics of image quality to aid in the design, implementation, and evaluation of CT image reconstruction algorithms and CT systems in general. We support the view…

Medical Physics · Physics 2015-05-18 Adrian A. Sanchez
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