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Low dose X-ray computed tomography (LDCT) is desirable for reduced patient dose. This work develops image reconstruction methods with deep learning (DL) regularization for LDCT. Our methods are based on unrolling of proximal…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoqiao Ding , Gaoyu Chen , Xiaoqun Zhang , Qiu Huang , Hui Jiand Hao Gao

Long lasting efforts have been made to reduce radiation dose and thus the potential radiation risk to the patient for computed tomography acquisitions without severe deterioration of image quality. To this end, numerous reconstruction and…

Medical Physics · Physics 2024-10-07 Elias Eulig , Björn Ommer , Marc Kachelrieß

Purpose: Optoacoustic tomography (OAT) is inherently a three-dimensional (3D) inverse problem. However, most studies of OAT image reconstruction still employ two-dimensional (2D) imaging models. One important reason is because 3D image…

Medical Physics · Physics 2013-04-09 Kun Wang , Chao Huang , Yu-Jiun Kao , Cheng-Ying Chou , Alexander A. Oraevsky , Mark A. Anastasio

We aim to investigate the impact of image and signal properties on visual attention mechanisms during a signal detection task in digital images. The application of insight yielded from this work spans many areas of digital imaging where…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Amar Kavuri , Howard C. Gifford , Mini Das

In practical applications of tomographic imaging, there are often challenges for image reconstruction due to under-sampling and insufficient data. In computed tomography (CT), for example, image reconstruction from few views would enable…

Medical Physics · Physics 2009-04-30 Emil Y. Sidky , Chien-Min Kao , Xiaochuan Pan

Computed tomography (CT) is a non-destructive technique for observing internal images and has proven highly valuable in medical diagnostics. Recent advances in quantum computing have begun to influence tomographic reconstruction techniques.…

Quantum Physics · Physics 2025-05-19 Arim Ryou , Kiwoong Kim , Kyungtaek Jun

While research has established the potential of AI models for mammography to improve breast cancer screening outcomes, there have not been any detailed subgroup evaluations performed to assess the strengths and weaknesses of commercial…

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Regularization methods are commonly used in X-ray CT image reconstruction. Different regularization methods reflect the characterization of different prior knowledge of images. In a recent work, a new regularization method called a…

Medical Physics · Physics 2017-04-18 Wenxiang Cong , Ge Wang , Qingsong Yang , Jiang Hsieh , Jia Li , Rongjie Lai

Filtered back projection (FBP) methods are the most widely used reconstruction algorithms in computerized tomography (CT). The ill-posedness of this inverse problem allows only an approximate reconstruction for given noisy data. Studying…

Numerical Analysis · Mathematics 2023-07-25 Matthias Beckmann , Peter Maass , Judith Nickel

Limited data and low dose constraints are common problems in a variety of tomographic reconstruction paradigms which lead to noisy and incomplete data. Over the past few years sinogram denoising has become an essential pre-processing step…

Computer Vision and Pattern Recognition · Computer Science 2016-03-15 Faisal Mahmood , Nauman Shahid , Pierre Vandergheynst , Ulf Skoglund

Imaging of teeth is very important to doctors in the diagnosis and treatment of dental diseases. The main imaging modality currently used is Cone-Beam Computed Tomography (CBCT), which however suffers from ionizing radiation causing…

Medical Physics · Physics 2023-04-13 Yuting Shen , Yiyun Wang , Chengxiao Liu , Niansong Ye , Feng Gao , Lunguo Xia , Bing Fang , Fei Gao

Diffusion Posterior Sampling (DPS) can be used in Computed Tomography (CT) reconstruction by leveraging diffusion-based generative models for unconditional image synthesis while matching the observations (data) of a CT scan. Of particular…

Convolutional neural networks (CNNs) have recently achieved remarkable performance in positron emission tomography (PET) image reconstruction. In particular, CNN-based direct PET image reconstruction, which directly generates the…

Medical Physics · Physics 2024-10-28 Fumio Hashimoto , Kibo Ote

Objective: In this work, we perform margin assessment of human breast tissue from optical coherence tomography (OCT) images using deep neural networks (DNNs). This work simulates an intraoperative setting for breast cancer lumpectomy.…

Breast cancer remains a global challenge, causing over 1 million deaths globally in 2018. To achieve earlier breast cancer detection, screening x-ray mammography is recommended by health organizations worldwide and has been estimated to…

A realistic computer-simulation of a breast computed tomography (CT) system and subject is constructed. The model is used to investigate the optimal number of views for the scan given a fixed total X-ray fluence. The reconstruction…

The segmentation of mass lesions in digital breast tomosynthesis (DBT) images is very significant for the early screening of breast cancer. However, the high-density breast tissue often leads to high concealment of the mass lesions, which…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Haoxuan Zhang , Wenju Cui , Yuzhu Cao , Tao Tan , Jie Liu , Yunsong Peng , Jian Zheng

Breast cancer is the most frequently diagnosed human cancer in the United States at present. Early detection is crucial for its successful treatment. X-ray mammography and digital breast tomosynthesis are currently the main methods for…

Deep learning (DL)-based image reconstruction methods for photoacoustic computed tomography (PACT) have developed rapidly in recent years. However, most existing methods have not employed standardized datasets, and their evaluations rely on…

Medical Physics · Physics 2026-01-27 Panpan Chen , Seonyeong Park , Gangwon Jeong , Refik Mert Cam , Umberto Villa , Mark A. Anastasio