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This study examines the flow of dense granular materials under external shear stress and pressure using discrete element method simulations. In this method, the material is allowed to strain along all periodic directions and adapt its solid…

Soft Condensed Matter · Physics 2020-11-24 Ishan Srivastava , Leonardo E. Silbert , Gary S. Grest , Jeremy B. Lechman

Porous bleed systems are a common technique to control shock-boundary layer interactions and/or supersonic boundary layers. However, the influence of various design parameters is still unknown. Even though bleed models are required to…

Fluid Dynamics · Physics 2023-12-01 Julian Giehler , Pierre Grenson , Reynald Bur

The shock-boundary layer interaction over the convex wall of a supersonic turbine vane is studied with a focus on extreme separation bubble events and the interplay between the bubble, streaks, and streamwise vortices. The present analysis…

Fluid Dynamics · Physics 2025-12-16 Hugo Lui , William Wolf

We exploit a two-dimensional model [7], [6] and [1] describing the elastic behavior of the wall of a flexible blood vessel which takes interaction with surrounding muscle tissue and the 3D fluid flow into account. We study time periodic…

Analysis of PDEs · Mathematics 2021-07-28 V. Kozlov , S. Nazarov , G. Zavorokhin

We are interested in a reduced order method for the efficient simulation of blood flow in arteries. The blood dynamics is modeled by means of the incompressible Navier-Stokes equations. Our algorithm is based on an approximated…

Numerical Analysis · Mathematics 2021-04-07 Luca Pegolotti , Martin Pfaller , Alison Marsden , Simone Deparis

A nonlinear model relating the imposed motion of a circular cylinder, submerged in a fluid flow, to the transverse force coefficient is presented. The nonlinear fluid system, featuring vortex shedding patterns, limit cycle oscillations and…

Fluid Dynamics · Physics 2020-06-11 Jan Decuyper , Tim De Troyer , Koen Tiels , Johan Schoukens , Mark C. Runacres

The emergence of computational fluid dynamics (CFD) enabled the simulation of intricate transport processes, including flow in physiological structures, such as blood vessels. While these so-called hemodynamic simulations offer…

The role of Helical Flow (HF) in human coronary arteries remains uncertain, yet its understanding promises unprecedented insights into atherosclerotic processes. In this study, we investigated the effects of HF and key haemodynamic…

Medical Physics · Physics 2025-08-12 Chi Shen , Mingzi Zhang , Hamed Keramati , Diogo Almeida , Susann Beier

The relationship between vascular morphology and hemodynamics is fundamental to understanding the natural history of cerebral aneurysms (CAs). While global geometric indices have been widely studied, the local interaction between luminal…

Medical Physics · Physics 2026-02-26 Marcella P. A. Dallavanzi , José L. Gasche , Iago L. Oliveira

This work develops a computational and theoretical framework for determining effective permeabilities in anisotropic microscopic geometries containing dense, fibre-like obstacles, motivated by the need to model flow in coiled aneurysm…

This work aims at identifying and quantifying uncertainties related to elastic and viscoelastic parameters, which characterize the arterial wall behavior, in one-dimensional modeling of the human arterial hemodynamics. The chosen uncertain…

Fluid Dynamics · Physics 2021-02-12 Giulia Bertaglia , Valerio Caleffi , Lorenzo Pareschi , Alessandro Valiani

Peristaltic pumping is hypothesized to drive fluid transport in several physiological systems, including cerebrospinal fluid flow through cerebral perivascular spaces (PVSs). Cerebral PVSs are unique in the context of peristaltic pumping…

Fluid Dynamics · Physics 2026-05-28 Shahaf Ella Salach , Ron Shnapp

The assumption that blood adheres to vessel walls, the ``no-slip'' boundary condition, is an essential premise of cardiovascular fluid dynamics. Yet, whether it holds true \emph{in vivo} has not been established. Using 4D flow magnetic…

This research aims to develop a method to reduce the time cost and complexity of balloon expandable stent simulations in cardiovascular stenting procedures for Peripheral Artery Disease. The study uses stereoscopic images to construct a…

Medical Physics · Physics 2025-05-27 Efstathios Stratakos , Vassilis Kostopoulos , Spyridon Psarras

Secondary interventions after endovascular repair of abdominal aortic aneurysms are frequent because stent-graft (SG) related complications may occur (mainly endoleak and SG thrombosis). Complications have been related to insufficient SG…

We analyse mathematical models in order to understand how microstructural features of vascular networks may affect blood-flow dynamics, and to identify particular characteristics that promote the onset of self-sustained oscillations. By…

Quantitative Methods · Quantitative Biology 2022-06-23 Yaron Ben-Ami , George W. Atkinson , Joe M. Pitt-Francis , Philip K. Maini , Helen M. Byrne

Purpose: To experimentally evaluate the effect of a Multilayer Flow Modulator (MFM) device deployment in an Abdominal Aortic Aneurysm (AAA) model with and without incorporated branch. Methods: An experimental flow and pressure monitoring…

Medical Physics · Physics 2020-11-19 Simon Tupin , Kei Takase , Makoto Ohta

We analyze the pressure-driven flow of a viscoelastic fluid in arbitrarily shaped, narrow channels and present a theoretical framework for calculating the relationship between the flow rate $q$ and pressure drop $\Delta p$. We utilize the…

Fluid Dynamics · Physics 2022-05-31 Evgeniy Boyko , Howard A. Stone

Rapid and accurate simulation of cerebral aneurysm flow modifications by flow diverters (FDs) can help improving patient-specific intervention and predicting treatment outcome. However, with explicit FD devices being placed in…

The dynamics of inertial particles in turbulence is modelled and investigated by means of direct numerical simulation of an axisymmetrically expanding homogeneous turbulent strained flow. This flow can mimic the dynamics of particles close…

Fluid Dynamics · Physics 2023-07-19 Chung-min Lee , Ármann Gylfason , Prasad Perlekar , Federico Toschi