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Single-stranded (ss) RNA viruses self-assemble spontaneously in solutions that contain the viral RNA genome molecules and the viral capsid proteins. The self-assembly of empty capsids can be understood on the basis of free energy…

Biological Physics · Physics 2021-08-21 Inbal Mizrahi , Robijn Bruinsma , Joseph Rudnick

Cellular functions are established through biological evolution, but are constrained by the laws of physics. For instance, the physics of protein folding limits the lengths of cellular polypeptide chains. Consequently, many cellular…

Biological Physics · Physics 2019-07-09 Pablo Sartori , Stanislas Leibler

Self-assembly processes are widespread in nature, and lie at the heart of many biological and physical phenomena. The characteristics of self-assembly building blocks determine the structures that they form. Two crucial properties are the…

Soft Condensed Matter · Physics 2018-09-11 S. Tesoro , S. E. Ahnert , A. S. Leonard

In this paper we study aggregation kinetics in systems of particles functionalised by complementary linkers. Most of the coarse-grained models currently employed to study large-scale self-assembly of these systems rely on effective…

Soft Condensed Matter · Physics 2018-12-24 S. J. Bachmann , M. Petitzon , B. M. Mognetti

Self-assembly of granular particles is of great interest in both applied and basic research. It is commonly observed that when randomly packed into a container, granular particles form disordered structures like glass. As the particles are…

Soft Condensed Matter · Physics 2025-01-20 Reza Amirifar , Kejun Dong , Aibing Yu

Large protein complexes are assembled from protein subunits to form a specific structure. In our theoretic work, we propose that assembly into the correct structure could be reliably achieved through an assembly line with a specific…

Biological Physics · Physics 2022-03-23 Tyler S. Harmon , Frank Jülicher

Using Monte Carlo simulations, we investigate the self-assembly of model nanoparticles inside a matrix of model equilibrium polymers (or matrix of Wormlike micelles) as a function of the polymeric matrix density and the excluded volume…

Soft Condensed Matter · Physics 2018-04-03 Sk. Mubeena , Apratim Chatterji

A major goal in nanoscience and nanotechnology is the self-assembly of any desired complex structure with a system of particles interacting through simple potentials. To achieve this objective, intense experimental and theoretical efforts…

Soft Condensed Matter · Physics 2014-09-11 Daniel Salgado-Blanco , Carlos I. Mendoza

We propose a description for the quasi-equilibrium self-assembly of small, single-stranded (ss) RNA viruses whose capsid proteins (CPs) have flexible, positively charged, disordered tails that associate with the negatively charged RNA…

Soft Condensed Matter · Physics 2016-03-23 Robijn F. Bruinsma , Mauricio Comas-Garcia , Rees F. Garmann , Alexander Y. Grosberg

Single-stranded (ss) RNA viruses self-assemble spontaneously in solutions that contain the viral RNA genome molecules and viral capsid proteins. The self-assembly of empty capsids can be understood on the basis of free energy minimization.…

Biological Physics · Physics 2022-03-22 Inbal Mizrahi , Robijn Bruinsma , Joseph Rudnick

Understanding the complex self-assembly of biomacromolecules is a major outstanding question. Microtubules are one example of a biopolymer that possesses characteristics quite distinct from standard synthetic polymers that are derived from…

Soft Condensed Matter · Physics 2013-01-10 Shengfeng Cheng , Ankush Aggarwal , Mark J. Stevens

One of the challenges of self-assembling finite-sized colloidal aggregates with a sought morphology is the necessity of precisely sorting the position of the colloids at the microscopic scale to avoid the formation of off-target structures.…

Soft Condensed Matter · Physics 2020-01-31 Pritam Kumar Jana , Bortolo Matteo Mognetti

The rapid progress in precisely designing the surface decoration of patchy colloidal particles offers a new, yet unexperienced freedom to create building entities for larger, more complex structures in soft matter systems. However, it is…

Soft Condensed Matter · Physics 2012-06-14 G. Doppelbauer , E. G. Noya , E. Bianchi , G. Kahl

In this review we discuss recent advances in the self-assembly of self-propelled colloidal particles and highlight some of the most exciting results in this field with a specific focus on dry active matter. We explore this phenomenology…

Soft Condensed Matter · Physics 2021-02-24 S. A. Mallory , C. Valeriani , A. Cacciuto

Patchy particles have proven to be a prominent model for studying the self-assembly behavior of various systems, ranging from finite clusters to bulk crystal assemblies, and from synthetic colloidal particles to viruses. The patchy particle…

Soft Condensed Matter · Physics 2025-10-13 Gregory Snyder , Chrisy Xiyu Du

We develop equilibrium and kinetic theories that describe the assembly of viral capsid proteins on a charged central core, as seen in recent experiments in which brome mosaic virus (BMV) capsids assemble around nanoparticles functionalized…

Biomolecules · Quantitative Biology 2009-05-06 Michael F. Hagan

It has recently been shown that identical, isotropic particles can form complex crystals and quasicrystals. In order to understand the relation between the particle interaction and the structure, which it stabilizes, the phase behavior of a…

Materials Science · Physics 2009-04-01 Michael Engel , Hans-Rainer Trebin

Particles with directional interactions are promising building blocks for new functional materials and may serve as models for biological structures. Mutually attractive nanoparticles that are deformable due to flexible surface groups, for…

Soft Condensed Matter · Physics 2016-07-19 Chris H. J. Evers , Jurriaan A. Luiken , Peter G. Bolhuis , Willem K. Kegel

Self-assembly kinetics is usually described by approaches which assume that the shape of the aggregates has a definite form (e.g., spherical, cylindrical, cubic, etc), however that is unlikely to be the case in many finite-sized…

Soft Condensed Matter · Physics 2022-07-13 L. F. Trugilho , L. G. Rizzi

Complex colloidal cluster morphologies are desirable for the fabrication of advanced materials, such as photonic crystals and meta-materials, and can be formed through evaporation-driven packing. By coupling lattice Boltzmann and discrete…

Soft Condensed Matter · Physics 2026-05-07 Junyu Yang , Abhinav Naga , Xitong Zhang , Halim Kusumaatmaja