Related papers: Mass-sensing BioCD Protein Array towards Clinical …
Prostate specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) imaging provides a tremendously exciting frontier in visualization of prostate cancer (PCa) metastatic lesions. However, accurate…
The immuno-infrared sensor detects target proteins in solution. Exemplary, the initial misfolding of amyloid beta (Abeta) peptides in blood is measured, enabling early risk prediction of Alzheimer's disease in the preclinical stage.…
Protein detection on SDS gels or on 2-D gels must combine several features, such as sensitivity, homogeneity from one protein to another, speed, low cost, and user-friendliness. For some applications, it is also interesting to have a…
Most technologies, including conventional mass spectrometry, struggle to measure the mass of particles in the MDa to GDa range. Although this mass range appears optimal for nanomechanical resonators, early nanomechanical-MS systems suffered…
We report multipass broadband photoacoustic spectroscopy of trace gases in the mid-infrared. The measurement principle of the sensor relies on supercontinuum-based Fourier transform photoacoustic spectroscopy (FT-PAS), in which a scanning…
In this paper, we propose using mobile nanosensors (MNSs) for early stage anomaly detection. For concreteness, we focus on the detection of cancer cells located in a particular region of a blood vessel. These cancer cells produce and emit…
This article reports on the development and experimental results of commercial plasma display panels adapted for their potential use as micropattern gas radiation detectors. The plasma panel sensors (PPS) design an materials include glass…
We present a hybrid surface-enhanced Raman spectroscopy (SERS) platform based on dielectric silicon metasurfaces integrated with functionalized graphene for the selective detection of biomolecules such as prolactin and SARS-CoV-2…
A wide range of methods currently exist for testing the presence of malaria, each with its own advantages and disadvantages. New technologies are urgently needed to develop more effective diagnosis tools to fight and eradicate malaria.…
Artificially engineered biosensors are highly inefficient in accurately measuring the concentration of biomarkers, particularly, during early diagnosis of diseases. On the other hand, single cellular systems such as chemotactic bacteria can…
A new type of gaseous micropattern particle detector based on a closed-cell microcavity plasma panel sensor is reported. The first device was fabricated with 1 x 1 x 2 mm cells. It has shown very clean signals of 0.6 to 2.5 volt amplitude,…
MicroRNAs (miRNAs) are an emerging class of biomarkers that are frequently deregulated in cancer cells and have shown a great promise for cancer classification and prognosis. In this work, we developed a three-way electrochemical sensor for…
The detection and analysis of circulating tumor cells (CTCs) may enable a broad range of cancer-related applications, including the identification of acquired drug resistance during treatments. However, the non-scalable fabrication,…
We propose a new optical biosensor based on a photonic crystal with a defect layer, which can determine the SARS-CoV-2 concentration in water by the defect mode shift. Two models of the dependence of the refractive index of the defect layer…
Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting…
Clinical biosensors with low detection limit hold significant promise in the early diagnosis of debilitating diseases. Recent progress in sensor development has led to the demonstration of detection capable of detecting target molecules…
A photoacoustic (PA) sensor for fast and real-time gas sensing is demonstrated. The PA sensor is a standalone system controlled by a Field-Programmable Gate Array (FPGA). The PA cell has been designed for flow noise immunity using…
We offer new high-performance label-free electrochemical impedimetric DNA sensors of non-faradaic type. The DNA sensors based on a platform of crystalline carbon nanotube (CNT) arrays are fabricated by the Langmuir--Blodgett (LB) deposition…
Prostate cancer (PCa) detection using deep learning (DL) models has shown potential for enhancing real-time guidance during biopsies. However, prostate ultrasound images lack pixel-level cancer annotations, introducing label noise. Current…
Antibody-functionalized silicon nanowire field-effect transistors have been shown to exhibit excellent analyte detection sensitivity enabling sensing of analyte concentrations at levels not readily accessible by other methods. One example…