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Collective cell migration is a highly regulated process involved in wound healing, cancer metastasis and morphogenesis. Mechanical interactions among cells provide an important regulatory mechanism to coordinate such collective motion.…

Soft Condensed Matter · Physics 2022-06-08 Xingbo Yang , Dapeng Bi , Michael Czajkowski , Matthias Merkel , M. Lisa Manning , M. Cristina Marchetti

We show that a flat two dimensional network of connected vertices, when stretched, may deform plastically by producing `pleats'; system spanning linear structures with width comparable to the lattice spacing, where the network overlaps on…

Soft Condensed Matter · Physics 2018-12-14 Saswati Ganguly , Debankur Das , Jürgen Horbach , Peter Sollich , Smarajit Karmakar , Surajit Sengupta

Dryland vegetation can survive water stress by forming spatial patterns but is often subjected to herbivory as an additional stress that puts it at risk of desertification. Understanding the mutual relationships between vegetation…

Populations and Evolution · Quantitative Biology 2026-02-17 Joydeep Singha , Hannes Uecker , Ehud Meron

A model for morphoelastic growth, that is, growth influenced by elastic stress, driven by the absorption of nutrients is considered. The model features a multiplicative decomposition of the deformation gradient into an elastic contribution…

Analysis of PDEs · Mathematics 2026-05-05 Helmut Abels , Julian Blawid , Georg Dolzmann

We introduce a model for the formation of social networks, which takes into account the homophily or the tendency of individuals to associate and bond with similar others, and the mechanisms of global and local attachment as well as tie…

Physics and Society · Physics 2019-03-28 Yohsuke Murase , Hang-Hyun Jo , János Török , János Kertész , Kimmo Kaski

Active stresses can cause instabilities in contractile gels and living tissues. Here we describe a generic hydrodynamic theory that treats these systems as a mixture of two phases of varying activity and different mechanical properties. We…

Biological Physics · Physics 2018-06-20 Christoph Weber , Chris H. Rycroft , L. Mahadevan

Survival of living tumor cells underlies many influences such as nutrient saturation, oxygen level, drug concentrations or mechanical forces. Data-supported mathematical modeling can be a powerful tool to get a better understanding of cell…

Dynamical Systems · Mathematics 2022-03-24 Sabrina Schönfeld , Alican Ozkan , Laura Scarabosio , Marissa Nichole Rylander , Christina Kuttler

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

Molecular Networks · Quantitative Biology 2007-05-23 Kanchan Thadani , Ashutosh

A fundamental theory is presented for the mechanical response of polymer networks undergoing large deformation which seamlessly integrates statistical mechanical principles with macroscopic thermodynamic constitutive theory. Our formulation…

Soft Condensed Matter · Physics 2020-07-06 Michael R. Buche , Meredith N. Silberstein

Modeling biological soft tissue is complex in part due to material heterogeneity. Microstructural patterns, which play a major role in defining the mechanical behavior of these tissues, are both challenging to characterize, and difficult to…

Machine Learning · Computer Science 2022-07-19 Hiba Kobeissi , Saeed Mohammadzadeh , Emma Lejeune

This paper introduces a linear state-space model with time-varying dynamics. The time dependency is obtained by forming the state dynamics matrix as a time-varying linear combination of a set of matrices. The time dependency of the weights…

Machine Learning · Statistics 2014-10-06 Jaakko Luttinen , Tapani Raiko , Alexander Ilin

The aim of this paper is to present the technique (and its linkage with physics) of overcoming problems connected to modeling social structures, which are typically hierarchical. Hierarchical Linear Models provide a conceptual and…

Physics and Society · Physics 2007-05-23 Magdalena Jelonek

Soft biological tissues exhibit a tendency to maintain a preferred state of tensile stress, known as tensional homeostasis, which is restored even after external mechanical stimuli. This macroscopic behavior can be described using the…

Machine Learning · Computer Science 2025-01-23 Hagen Holthusen , Tim Brepols , Kevin Linka , Ellen Kuhl

Systems composed of distinct complex networks are present in many real-world environments, from society to ecological systems. In the present paper, we propose a network model obtained as a consequence of interactions between two species…

Biological Physics · Physics 2007-08-08 Luis Enrique Correa da Rocha , Luciano da Fontoura Costa

Many biological systems and artificial structures are ramified, and present a high geometric complexity. In this work, we propose a space-averaged model of branched systems for conservation laws. From a one-dimensional description of the…

Computational Physics · Physics 2014-10-13 Diego Lopez , Emmanuel de Langre , Sébastien Michelin

We present a solid state system which spontaneously generates remarkable engraving patterns on the surface of Ge. The layered construction, with a metal film on the Ge surface, results in coupling of the metal catalyzed etching reaction…

Materials Science · Physics 2024-06-03 Yilin Wong , Giovanni Zocchi

Understanding the evolution of binary traits, which affects the birth and survival of species and also the rate of molecular evolution, remains challenging. A typical example is the evolution of mating systems in plant species. In this…

Populations and Evolution · Quantitative Biology 2017-04-04 Daniah Tahir , Sylvain Glémin , Martin Lascoux , Ingemar Kaj

Network motifs are characteristic patterns which occur in the networks essentially more frequently than the other patterns. For five motifs found in S. Itzkovitz, U. Alon, Phys. Rev.~E, 2005, 71, 026117-1, hierarchical random graphs are…

Mathematical Physics · Physics 2015-04-02 Monika Kotorowicz , Yuri Kozitsky

We explain the principles of gene expression pattern stabilization in systems of interacting, diffusible morphogens, with dynamically established source regions. Using a reaction-diffusion model with step-function production term, we…

Biological Physics · Physics 2023-03-02 M. Majka , R. D. J. G. Ho , M. Zagorski

We introduce two 2D mechanical models reproducing the evolution of two viscous tissues in contact. Their main property is to model the swirling cell motions while keeping the tissues segregated, as observed during vertebrate embryo…

Analysis of PDEs · Mathematics 2022-03-25 Pierre Degond , Sophie Hecht , Michèle Romanos , Ariane Trescases
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