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In this paper, we consider an integrated MSP-MDP framework which captures features of Markov decision process (MDP) and multistage stochastic programming (MSP). The integrated framework allows one to study a dynamic decision-making process…

Optimization and Control · Mathematics 2025-09-29 Zhiyao Yang , Zhiping Chen , Huifu Xu

We investigate the appearance of trapping states in pedestrian flows through bottlenecks as a result of the interplay between the geometry of the system and the microscopic stochastic dynamics. We model the flow trough a bottleneck via a…

Statistical Mechanics · Physics 2017-08-23 Emilio N. M. Cirillo , Matteo Colangeli , Adrian Muntean

Flexible modulation of temporal dynamics in neural sequences underlies many cognitive processes. For instance, we can adaptively change the speed of motor sequences and speech. While such flexibility is influenced by various factors such as…

Neurons and Cognition · Quantitative Biology 2025-04-15 Tomoki Kurikawa , Kunihiko Kaneko

Langer theory of metastability provides a description of the lifetime and properties of the metastable phase of the Ising model field-driven transition, describing the magnetic field-driven transition in ferromagnets and the chemical…

Statistical Mechanics · Physics 2015-06-19 Miguel Ibáñez Berganza , Pietro Coletti , Alberto Petri

A constant-rate multi-mode system is a hybrid system that can switch freely among a finite set of modes, and whose dynamics is specified by a finite number of real-valued variables with mode-dependent constant rates. We introduce and study…

Optimization and Control · Mathematics 2016-10-19 Fabio Somenzi , Behrouz Touri , Ashutosh Trivedi

Constraint tightening to non-conservatively guarantee recursive feasibility and stability in Stochastic Model Predictive Control is addressed. Stability and feasibility requirements are considered separately, highlighting the difference…

Systems and Control · Computer Science 2016-05-13 Matthias Lorenzen , Fabrizio Dabbene , Roberto Tempo , Frank Allgöwer

Noise caused by fluctuations at the molecular level is a fundamental part of intracellular processes. While the response of biological systems to noise has been studied extensively, there has been limited understanding of how to exploit it…

Molecular Networks · Quantitative Biology 2015-10-14 Daniel K. Wells , William L. Kath , Adilson E. Motter

Physically motivated stochastic dynamics are often used to sample from high-dimensional distributions. However such dynamics often get stuck in specific regions of their state space and mix very slowly to the desired stationary state. This…

Machine Learning · Statistics 2025-05-13 Abhijith Jayakumar , Andrey Y. Lokhov , Sidhant Misra , Marc Vuffray

We prove the metastable behavior of reversible Markov processes on finite state spaces under minimal conditions on the jump rates. To illustrate the result we deduce the metastable behavior of the Ising model with a small magnetic field at…

Probability · Mathematics 2010-09-22 Johel Beltran , Claudio Landim

Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…

Neurons and Cognition · Quantitative Biology 2022-04-01 Braden A. W. Brinkman , Han Yan , Arianna Maffei , Il Memming Park , Alfredo Fontanini , Jin Wang , Giancarlo La Camera

We report on linear spin dynamics in the vortex state of the Permalloy dots subjected to stratified (magnetic) field. We demonstrate experimentally and by simulations the existence of two distinct dynamic regimes corresponding to the vortex…

We present an explicit construction of the Freidlin-Wentzell quasipotential of a stochastic system with two degrees of freedom and nonreciprocal interactions. This model undergoes noise-induced transitions between four metastable…

Statistical Mechanics · Physics 2025-12-10 Janik Schüttler , Robert L. Jack , Michael E. Cates

We investigate dynamical many-body systems capable of universal computation, which leads to their properties being unpredictable unless the dynamics is simulated from the beginning to the end. Unpredictable behavior can be quantitatively…

Quantum Physics · Physics 2021-06-16 Javad Kazemi , Hendrik Weimer

This work extends the results of the recently developed theory of a rather complete thermodynamic formalism for discrete-state, continuous-time Markov processes with and without detailed balance. We aim at investigating the question that…

Statistical Mechanics · Physics 2011-05-30 Moises Santillan , Hong Qian

The paper concerns the construction of a compressible liquid-vapor relaxation model which is able to capture the metastable states of the non isothermal van der Waals model as well as saturation states. Starting from the Gibbs formalism, we…

Analysis of PDEs · Mathematics 2019-11-01 Hala Ghazi , Francois James , Hélène Mathis

We consider a family of multi-phase Stefan problems for a certain 1-d model of cell-to-cell adhesion and diffusion, which takes the form of a nonlinear forward-backward parabolic equation. In each material phase the cell density stays…

Analysis of PDEs · Mathematics 2010-08-04 K. Anguige

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

Statistical Mechanics · Physics 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

Bistability is considered wide-spread among bacteria and eukaryotic cells, useful e.g. for enzyme induction, bet hedging, and epigenetic switching. However, this phenomenon has mostly been described with deterministic dynamic or well-mixed…

Subcellular Processes · Quantitative Biology 2017-02-08 Robert G. Endres

In this paper, the problem of non-fragile finite-time stabilization for linear discrete mean-field stochastic systems is studied. The uncertain characteristics in control parameters are assumed to be random satisfying the Bernoulli…

Optimization and Control · Mathematics 2023-01-24 Tianliang Zhang , Feiqi Deng , Peng Shi

The Lotka-Volterra model of competition has been studied by numerical simulations using the Runge-Kutta-Fehlberg algorithm. The stable fixed points, unstable fixed point, saddle node, basins of attraction, and the separatices are found. The…

Populations and Evolution · Quantitative Biology 2023-11-21 Sauvik Chatterjee , Muktish Acharyya