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We introduce a multi-species diffuse interface model for tumor growth, characterized by its incorporation of essential features related to chemotaxis, angiogenesis and proliferation mechanisms. We establish the weak well-posedness of the…

Analysis of PDEs · Mathematics 2023-11-23 Abramo Agosti , Andrea Signori

We study a chemotaxis-consumption mechanism, in which some chemical signal and cells density interact each other. In order to control the concentration of such a population, sources involving gradient nonlinearities, which introduce a…

Analysis of PDEs · Mathematics 2025-01-24 Daniel Acosta Soba , Alessandro Columbu , Giuseppe Viglialoro

This paper is concerned with the density-suppressed motility model: $u_{t}=\Delta (\displaystyle\frac{u^m}{v^\alpha}) +\beta uf(w), v_{t}=D\Delta v-v+u, w_{t}=\Delta w-uf(w)$ in a smoothly bounded convex domain $\Omega\subset…

Analysis of PDEs · Mathematics 2021-03-04 Chi Xu , Yifu Wang

In this paper, we investigate the long-time dynamics of a repulsive Keller-Segel chemotaxis system. The model features negative chemotaxis, logistic growth and a cell death term, accounting for a lethal chemorepellent that is self-produced…

Analysis of PDEs · Mathematics 2026-04-20 Federico Herrero-Hervás , Mihaela Negreanu

This paper is concerned with the global boundedness and blowup of solutions to the Keller-Segel system with density-dependent motility in a two-dimensional bounded smooth domain with Neumman boundary conditions. We show that if the motility…

Analysis of PDEs · Mathematics 2020-05-14 Hai-Yang Jin , Zhi-An Wang

This study deals with continuous limits of interacting one-dimensional diffusive systems, arising from stochastic distortions of discrete curves with various kinds of coding representations. These systems are essentially of a…

Statistical Mechanics · Physics 2011-09-09 Guy Fayolle , Cyril Furtlehner

We study an one{dimensional quasilinear system proposed by J. Tello and M. Winkler [19] which models the population dynamics of two competing species attracted by the same chemical. The kinetics terms of the interacting species are chosen…

Analysis of PDEs · Mathematics 2016-11-25 Jia Hu , Qi Wang , Jingyue Yang , Lu Zhang

A Keller-Segel model describes macroscopic dynamics of bacterial colonies and biological cells. Bacteria secret chemical which attracts other bacteria so that they move towards chemical gradient creating nonlocal attraction between…

Pattern Formation and Solitons · Physics 2010-05-18 Pavel M. Lushnikov

The Keller--Segel PDE is a model for chemotaxis known to exhibit possible finite-time blow-up. Following a seminal work by Tello and Winkler, a logistic damping term is added in this PDE and local well-posedness of mild solutions is proven.…

Probability · Mathematics 2025-12-24 Thomas Cavallazzi , Alexandre Richard , Milica Tomasevic

We discuss several continuum cell-cell adhesion models based on the underlying microscopic assumptions. We propose an improvement on these models leading to sharp fronts and intermingling invasion fronts between different cell type…

Cell Behavior · Quantitative Biology 2019-01-11 Jose A. Carrillo , Hideki Murakawa , Makoto Sato , Hideru Togashi , Olena Trush

We consider a multiscale stochastic compartmental model with three types of cells (stem cells, immature cells and mature cells) which combines cell proliferation and cell differentiation. We derive a hydrodynamic limit when the number of…

Probability · Mathematics 2026-03-10 Vincent Bansaye , Ana Fernández Baranda , Stéphane Giraudier , Sylvie Méléard

The goal of this paper is to exhibit a critical mass phenomenon occuring in a model for cell self-organization via chemotaxis. The very well known dichotomy arising in the behavior of the macroscopic Keller-Segel system is derived at the…

Analysis of PDEs · Mathematics 2015-05-13 Nikolaos Bournaveas , Vincent Calvez

We study a Keller-Segel type chemotaxis model with a modified sensitivity function in a bounded domain $\Omega\subset \mathbb{R}^N$, $N\geq2$. The global existence of classical solutions to the fully parabolic system is established provided…

Analysis of PDEs · Mathematics 2015-05-26 Qi Wang

We consider a partial differential equation model for the growth of heterogeneous cell populations subdivided into multiple distinct discrete phenotypes. In this model, cells preferentially move towards regions where they feel less…

Analysis of PDEs · Mathematics 2025-04-04 José A. Carrillo , Tommaso Lorenzi , Fiona R. Macfarlane

We investigate the convergence of solutions of a recently proposed diffuse interface/phase field model for cell blebbing by means of matched asymptotic expansions. It is a biological phenomenon that increasingly attracts attention by both…

Analysis of PDEs · Mathematics 2023-02-10 Philipp Nöldner , Martin Burger , Harald Garcke

The Keller-Segel-Navier-Stokes system governs chemotaxis in liquid environments. This system is to be solved for the organism and chemoattractant densities and for the fluid velocity and pressure. It is known that if the total initial cell…

Numerical Analysis · Mathematics 2023-02-02 Jesús Bonilla , Juan Vicente Gutiérrez-Santacreu

While the role of local interactions in nonequilibrium phase transitions is well studied, a fundamental understanding of the effects of long-range interactions is lacking. We study the critical dynamics of reproducing agents subject to…

Statistical Mechanics · Physics 2023-08-25 Jasper van der Kolk , Florian Rasshofer , Richard Swiderski , Astik Haldar , Abhik Basu , Erwin Frey

The Keller-Segel model is a system of partial differential equations that describes the movement of cells or organisms in response to chemical signals, a phenomenon known as chemotaxis. In this study, we analyze a doubly parabolic…

Analysis of PDEs · Mathematics 2025-03-27 Anne Caroline Bronzi , Crystianne Lilian de Andrade

The Cauchy problem for the parabolic--elliptic Keller--Segel system in the whole $n$-dimensional space is studied. For this model, every constant $A \in \mathbb{R}$ is a stationary solution. The main goal of this work is to show that $A <…

Analysis of PDEs · Mathematics 2021-01-06 Szymon Cygan , Grzegorz Karch , Krzysztof Krawczyk , Hiroshi Wakui

We introduce a two-dimensional Keller-Segel type free boundary model for motility of eukaryotic cells on substrates. The key ingredients of this model are the Darcy law for overdamped motion of the cytoskeleton (active) gel and Hele-Shaw…

Analysis of PDEs · Mathematics 2019-07-30 Leonid Berlyand , Volodymyr Rybalko