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We consider the singular limit of a chemotaxis model of bacterial collective motion recently introduced in arXiv:2009.11048 [math.AP]. The equation models aggregation-diffusion phenomena with advection that is discontinuous and depends…

Analysis of PDEs · Mathematics 2025-08-28 Maria Gualdani , Mikel Ispizua , Nicola Zamponi

We study the stationary Keller--Segel chemotaxis models with logistic cellular growth over a one-dimensional region subject to the Neumann boundary condition. We show that nonconstant solutions emerge in the sense of Turing's instability as…

Analysis of PDEs · Mathematics 2016-04-19 Qi Wang , Jingda Yan , Chunyi Gai

We are interested in the dynamical behaviors of solutions to a parabolic-parabolic chemotaxis-consumption model with a volume-filling effect on a bounded interval, where the physical no-flux boundary condition for the bacteria and mixed…

Analysis of PDEs · Mathematics 2024-12-17 Xiaowen Li , Jingyu Li

This paper is devoted to constructing approximate solutions for the classical Keller--Segel model governing \emph{chemotaxis}. It consists of a system of nonlinear parabolic equations, where the unknowns are the average density of cells (or…

Numerical Analysis · Mathematics 2024-02-13 Juan Vicente Gutiérrez-Santacreu , José Rafael Rodríguez-Galván

We consider a model of congestion dynamics with chemotaxis: The density of cells follows a chemical signal it generates, while subject to an incompressibility constraint. The incompressibility constraint results in the formation of patches,…

Analysis of PDEs · Mathematics 2023-01-18 Inwon Kim , Antoine Mellet , Yijing Wu

We consider a system of two coupled parabolic PDEs introduced in [1] to model motility of eukaryotic cells. We study the asymptotic behavior of solutions in the limit of a small parameter related to the width of the interface in phase field…

Analysis of PDEs · Mathematics 2016-02-05 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

The purpose of this work is to propose a non-Markovian and nonlinear model of subdiffusive transport that involves adhesion affects the cells escape rates form position x, with chemotaxis. This leads the escape rates to be dependent on the…

Cell Behavior · Quantitative Biology 2016-03-02 Akram Al-Sabbagh

Convergence of solutions to a partially diffusive chemotaxis system with indirect signal production and phenotype switching is shown in a two-dimensional setting when the switching rate increases to infinity, thereby providing a rigorous…

Analysis of PDEs · Mathematics 2024-10-10 Philippe Laurençot , Christian Stinner

In this paper we study a general class of hybrid mathematical models of collective motions of cells under the influence of chemical stimuli. The models are hybrid in the sense that cells are discrete entities given by ODE, while the…

Analysis of PDEs · Mathematics 2022-02-01 Roberto Natalini , Thierry Paul

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

We present initial results regarding the existence, stability and interaction of linear and nonlinear vibrational modes in a system of two coupled, one dimensional lattices with unequal numbers of masses. The effects on these nonlinear…

Biological Physics · Physics 2007-05-23 Kyle Forinash

In this paper we present an individual-based mechanical model that describes the dynamics of two contiguous cell populations with different proliferative and mechanical characteristics. An off-lattice modelling approach is considered…

Analysis of PDEs · Mathematics 2020-01-14 Tommaso Lorenzi , Philip J. Murray , Mariya Ptashnyk

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho

We study the existence of steady states to the Keller-Segel system with linear chemotactical sensitivity function on a smooth bounded domain in $\mathbb R^N,$ $N\ge3,$ having rotational symmetry. We find three different types of…

Analysis of PDEs · Mathematics 2016-03-22 Oscar Agudelo , Angela Pistoia

In this paper, we study the relationship between a diffusive model and a non-diffusive model which are both derived from the well-known Keller-Segel model, as a coefficient of diffusion $\varepsilon$ goes to zero. First, we establish the…

Analysis of PDEs · Mathematics 2015-06-11 Hongyun Peng , Huanyao Wen , Changjiang Zhu

We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…

Analysis of PDEs · Mathematics 2013-02-20 Ibrahim Fatkullin

A class of parabolic-parabolic Keller-Segel systems with degenerate diffusion and volume filling is studied in a bounded domain subject to no-flux boundary conditions. The equations are derived from a multiphase fluid model. The interplay…

Analysis of PDEs · Mathematics 2026-05-21 Noah Geltner , Ansgar Jüngel , Mingyue Zhang

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

The Keller-Segel system describes the collective motion of cells that are attracted by a chemical substance and are able to emit it. In its simplest form, it is a conservative drift-diffusion equation for the cell density coupled to an…

Analysis of PDEs · Mathematics 2010-10-29 Adrien Blanchet , Jean Dolbeault , Miguel Escobedo , Javier Fernández

The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…

Analysis of PDEs · Mathematics 2009-11-11 Carlos Escudero