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We analyze the effects of spatially extended periodic forcing on the dynamics of one-dimensional excitation waves. Entrainment of unstable primary waves has been studied numerically for different amplitudes and frequencies of additional…

Chaotic Dynamics · Physics 2011-06-03 Joseph M. Starobin , Vivek Varadarajan

We study the dynamics of a simple adaptive system in the presence of noise and periodic damping. The system is composed by two paths connecting a source and a sink, the dynamics is governed by equations that usually describe food search of…

Statistical Mechanics · Physics 2021-12-23 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

Adaptation and Self-Organizing Systems · Physics 2022-02-01 Ria Ghosh , Shakti N. Menon

Influence of mesoscopic channel noise on excitable dynamics of living cells became a hot subject within the last decade, and the traditional biophysical models of neuronal dynamics such as Hodgkin-Huxley model have been generalized to…

Neurons and Cognition · Quantitative Biology 2014-09-24 Igor Goychuk

Being an example for a relaxation oscillator, the FitzHugh-Nagumo model has been widely employed for describing the generation of action potentials. In this paper, we begin with a biological interpretation of what the subsequent…

Numerical Analysis · Mathematics 2025-01-31 Burcu Gürbüz , Aytül Gökçe , Mahmut Modanlı

We present a new model for the dynamics of the presynaptic intracellular calcium concentration in neurons evoked by various stimulation protocols. The aim of the model is twofold: We want to discuss the calcium transients during and after…

Biological Physics · Physics 2007-05-23 Michael Meyer-Hermann , Frido Erler , Gerhard Soff

We analyze an inhomogeneous system of coupled reaction-diffusion equations representing the dynamics of gene expression during differentiation of nerve cells. The outcome of this developmental phase is the formation of distinct functional…

Analysis of PDEs · Mathematics 2014-08-28 Benoit Perthame , Cristobal Quiñinao , Jonathan Touboul

We have analyzed the interplay between noise and periodic modulations in a mean field model of a neural excitable medium. To this purpose, we have considered two types of modulations; namely, variations of the resistance and oscillations of…

Statistical Mechanics · Physics 2016-08-15 J. M. G. Vilar , R. V. Solé , J. M. Rubí

The analysis of noise-induced escape in populations of bistable elements is challenging, because nonlinearity, coupling, and noise all play essential roles. We show that the interplay of these three factors yields three qualitatively…

Adaptation and Self-Organizing Systems · Physics 2026-03-06 Hidemasa Ishii , Hiroshi Kori

We propose a simple discrete stochastic model for calcium dynamics in living cells. Specifically, the calcium concentration distribution is assumed to give rise to a set of probabilities for the opening/closing of channels which release…

patt-sol · Physics 2009-10-31 Markus Baer , Martin Falcke , Herbert Levine , Lev S. Tsimring

We review theoretical models of individual motility as well as collective dynamics and pattern formation of active particles. We focus on simple models of active dynamics with a particular emphasis on nonlinear and stochastic dynamics of…

Other Condensed Matter · Physics 2015-06-04 Pawel Romanczuk , Markus Bär , Werner Ebeling , Benjamin Lindner , Lutz Schimansky-Geier

The present study investigates the spatio-temporal variability in the dynamics of self-sustained supersonic reaction waves propagating through an excitable medium. The model is an extension of Fickett's detonation model with a state…

Fluid Dynamics · Physics 2013-05-29 Matei I. Radulescu , Justin Tang

Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within individual cells, cells must effectively exchange…

Biological Physics · Physics 2022-10-12 Guanyu Li , Ryan LeFebre , Alia Starman , Patrick Chappell , Andrew Mugler , Bo Sun

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

We analyze a model of mutually-propelled filaments suspended in a two-dimensional solvent. The system undergoes a mean-field isotropic-nematic transition for large enough filament concentrations and the nematic order parameter is allowed to…

Soft Condensed Matter · Physics 2011-05-26 L. Giomi , L. Mahadevan , B. Chakraborty , M. F. Hagan

A large number of biological systems - from bacteria to sheep - can be described as ensembles of self-propelled agents (active particles) with a complex internal dynamic that controls the agent's behavior: resting, moving slow, moving fast,…

Biological Physics · Physics 2021-09-03 L. Gómez-Nava , T. Goudon , F. Peruani

The dynamic range measures the capacity of a system to discriminate the intensity of an external stimulus. Such an ability is fundamental for living beings to survive: to leverage resources and to avoid danger. Consequently, the larger is…

Neurons and Cognition · Quantitative Biology 2012-05-02 Leonardo L. Gollo , Claudio Mirasso , Víctor M. Eguíluz

We propose a neural network model of multi-neuron interacting system that simulates neurons to interact each other through the surroundings of neuronal cell bodies. We physically model the neuronal cell surroundings, include the dendrites,…

Neurons and Cognition · Quantitative Biology 2021-07-05 Yu-Juan Sun , Wei-Min Zhang

We model the spatiotemporal dynamics of cellular protein concentrations near membranes composed of different lipids using a three-variable continuum model for membrane-bound protein, cytosolic protein, and the local composition of a binary…

Soft Condensed Matter · Physics 2026-03-26 Benjamin Winkler , Sergio Alonso , Markus Bär

Many extended chemical and biological systems self-organise into complex patterns that drive the medium behaviour in a non-linear fashion. An important class of such systems are excitable media, including neural and cardiac tissues. In…

Other Quantitative Biology · Quantitative Biology 2024-09-09 Louise Arno , Desmond Kabus , Hans Dierckx
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