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The prospect of new biological and industrial applications that require communication in micro-scale, encourages research on the design of bio-compatible communication networks using networking primitives already available in nature. One of…

Information Theory · Computer Science 2012-05-23 Arash Einolghozati , Mohsen Sardari , Ahmad Beirami , Faramarz Fekri

Quorum sensing is the mechanism by which bacteria communicate and synchronize group behaviors. Quantitative information on parameters such as the copy number of particular quorum-sensing proteins should contribute strongly to understanding…

Quantitative Methods · Quantitative Biology 2015-05-14 Shu-Wen Teng , Yufang Wang , Kimberly C. Tu , Tao Long , Pankaj Mehta , Ned S. Wingreen , Bonnie L. Bassler , N. P. Ong

We study a generic model for quorum-sensing bacteria in circular confinement. Every bacterium produces signaling molecules, the local concentration of which triggers a response when a certain threshold is reached. If this response lowers…

Soft Condensed Matter · Physics 2016-02-22 Markus Rein , Nike Heinß , Friederike Schmid , Thomas Speck

Bacteria sense a diverse range of environmental analytes with high sensitivity and temporal resolution. Engineering and synthetic biology approaches enabled harnessing this capability through development of whole-cell biosensors that…

\textit{Vibrio harveyi} and \textit{Vibrio cholerae} have quorum sensing pathways with similar design and highly homologous components including multiple small RNAs (sRNAs). However, the associated luminescence phenotypes of strains with…

Molecular Networks · Quantitative Biology 2015-03-18 Andrew T Fenley , Suman K Banik , Rahul V Kulkarni

Molecular Communication (MC) utilizes chemical molecules to transmit information, introducing innovative strategies for pharmaceutical interventions and enhanced immune system monitoring. This paper explores Molecular communication based…

Biomolecules · Quantitative Biology 2024-12-31 Shees Zulfiqar , Ozgur B. Akan

BACKGROUND. Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carried out in response to complex environmental signals in the…

Molecular Networks · Quantitative Biology 2007-05-23 Illes J. Farkas , Chuang Wu , Chakra Chennubhotla , Ivet Bahar , Zoltan N. Oltvai

Electrochemical communication is a mechanism that enables intercellular interaction among bacteria within communities. Bacteria achieves synchronization and coordinates collective actions at the population level through the utilization of…

Information Theory · Computer Science 2024-03-15 Nithin V. Sabu , Bige Deniz Unluturk

Microbial communities frequently communicate via quorum sensing (QS), where cells produce, secrete, and respond to a threshold level of an autoinducer (AI) molecule, thereby modulating gene expression. However, the biology of QS remains…

Molecular Networks · Quantitative Biology 2017-08-02 Tahir Yusufaly , James Q. Boedicker

This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-01-21 Adam Noel , Karen C. Cheung , Robert Schober

Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…

Cell Behavior · Quantitative Biology 2018-02-14 Adam Noel , Yuting Fang , Nan Yang , Dimitrios Makrakis , Andrew W. Eckford

The social organization of microorganisms has long been a fascinating and challenging subject in both biology and sociology. In these organisms, the role of the individual is far less dominant than that of the community, which functions as…

Biological Physics · Physics 2025-03-05 Eleonora Alfinito , Matteo Beccaria

Information processing in the mammalian brain relies on a careful regulation of the membrane potential dynamics of its constituent neurons, which propagates across the neuronal tissue via electrical signalling. We recently reported the…

Neurons and Cognition · Quantitative Biology 2019-02-19 Rosa Martinez-Corral , Jintao Liu , Arthur Prindle , Gurol M. Suel , Jordi Garcia-Ojalvo

Many bacterial species exchange signaling molecules to coordinate population-wide responses. For this process known as quorum sensing the concentration of the respective molecules is crucial. Here we consider the interaction between…

Biological Physics · Physics 2018-11-14 Vera Bettenworth , Matthew McIntosh , Anke Becker , Bruno Eckhardt

Bacteria possess diverse mechanisms to regulate their motility in response to environmental and physiological signals, enabling them to navigate complex habitats and adapt their behavior. Among these mechanisms, interspecies recognition…

Populations and Evolution · Quantitative Biology 2025-12-01 Mattia Mattei , David Soriano Paños , Mahantesh Halappanavar , Alex Arenas

In bacterial populations, cells are able to cooperate in order to yield complex collective functionalities. Interest in population-level cellular behaviour is increasing, due to both our expanding knowledge of the underlying biological…

Multiagent Systems · Computer Science 2012-11-07 Angel Goni-Moreno , Martyn Amos

Information transmission in biological signaling circuits has often been described using the metaphor of a noise filter. Cellular systems need accurate, real-time data about their environmental conditions, but the biochemical reaction…

Molecular Networks · Quantitative Biology 2019-02-27 David Hathcock , James Sheehy , Casey Weisenberger , Efe Ilker , Michael Hinczewski

Escherichia coli has long been used as a model organism due to the extensive experimental characterization of its pathways and molecular components. Take chemotaxis as an example, which allows bacteria to sense and swim in response to…

Cell Behavior · Quantitative Biology 2015-12-09 Gabriele Micali , Robert G. Endres

Sensory systems have evolved to respond to input stimuli of certain statistical properties, and to reliably transmit this information through biochemical pathways. Hence, for an experimentally well-characterized sensory system, one ought to…

Cell Behavior · Quantitative Biology 2014-10-30 Diana Clausznitzer , Gabriele Micali , Silke Neumann , Victor Sourjik , Robert G. Endres

Motivation: One of the branches of Systems Biology is focused on a deep understanding of underlying regulatory networks through the analysis of the biomolecules oscillations and their interplay. Synthetic Biology exploits gene or/and…

Molecular Networks · Quantitative Biology 2020-11-30 Francesco Bardozzo , Pietro Liò , Roberto Tagliaferri