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We distinguish a mechanical representation of the world in terms of point masses with positions and momenta and the chemical representation of the world in terms of populations of different individuals, each with intrinsic stochasticity,…

Statistical Mechanics · Physics 2019-05-07 Hong Qian

We study a mechanism for reliable switching in biomolecular signal-transduction cascades. Steady bistable states are created by system-size cooperative effects in populations of proteins, in spite of the fact that the phosphorylation-state…

Subcellular Processes · Quantitative Biology 2015-05-30 Eric Smith , Supriya Krishnamurthy , Walter Fontana , David Krakauer

We show that the thermodynamic limit of a bistable phosphorylation-dephosphorylation cycle has a selection rule for the "more stable" macroscopic steady state. The analysis is akin to the Maxwell construction. Based on the chemical master…

Chemical Physics · Physics 2010-05-28 Hao Ge , Hong Qian

The dynamic phase transition has been studied in the two dimensional kinetic Ising model in presence of a time varying (sinusoidal) magnetic field by Monte Carlo simulation. The nature (continuous or discontinuous) of the transition is…

Statistical Mechanics · Physics 2009-10-31 Muktish Acharyya

The study of nonequilibrium steady-state (NESS) in the Ising model offers rich insights into the properties of complex systems far from equilibrium. This paper explores the nature of NESS phase transitions in two-dimensional (2D)…

Statistical Mechanics · Physics 2024-09-05 Dagne Wordofa Tola , Mulugeta Bekele

Multistability of mesoscopic, driven biochemical reaction systems has implications to a wide range of cellular processes. Using several simple models, we show that one class of bistable chemical systems has a deterministic counterpart in…

Chemical Physics · Physics 2010-11-12 Yunxin Zhang , Hao Ge , Hong Qian

Unlike equilibrium statistical mechanics, with its well-established foundations, a similar widely-accepted framework for non-equilibrium statistical mechanics (NESM) remains elusive. Here, we review some of the many recent activities on…

Statistical Mechanics · Physics 2015-05-30 T. Chou , K. Mallick , R. K. P. Zia

We give an introduction to phase transitions in the steady states of systems that evolve stochastically with equilibrium and nonequilibrium dynamics, the latter defined as those that do not possess a time-reversal symmetry. We try as much…

Statistical Mechanics · Physics 2009-11-11 R. A. Blythe

The nonequilibrium phase transition in a system of diffusing, coagulating particles in the presence of a steady input and evaporation of particles is studied. The system undergoes a transition from a phase in which the average number of…

Statistical Mechanics · Physics 2009-11-10 R. Rajesh

We numerically and analytically investigate the behavior of a non-equilibrium phase transition in the second Schl\"ogl autocatalytic reaction scheme. Our model incorporates both an interaction-induced phase separation and a bifurcation in…

Statistical Mechanics · Physics 2023-11-02 Reda Tiani , Uwe C. Täuber

Dual phospho/dephosphorylation cycles, as well as covalent enzymatic-catalyzed modifications of substrates, are widely diffused within cellular systems and are crucial for the control of complex responses such as learning, memory and…

Biological Physics · Physics 2015-05-28 A. Bazzani , G. Castellani , E. Giampieri , D. Remondini , L. N Cooper

Statistical physics provides a useful perspective for the analysis of many complex systems; it allows us to relate microscopic fluctuations to macroscopic observations. Developmental biology, but also cell biology more generally, are…

Cell Behavior · Quantitative Biology 2020-11-10 Anissa Guillemin , Michael P. H. Stumpf

We establish a set of nonequilibrium quantum phase transitions in the Ising model driven under monochromatic nonadiabatic modulation of the transverse field. We show that besides the Ising-like critical behavior, the system exhibits an…

Quantum Physics · Physics 2013-01-03 V. M. Bastidas , C. Emary , G. Schaller , T. Brandes

Noise-induced transitions between metastable fixed points in systems evolving on multiple time scales are analyzed in situations where the time scale separation gives rise to a slow manifold with bifurcation. This analysis is performed…

Statistical Mechanics · Physics 2017-10-05 Tobias Grafke , Eric Vanden-Eijnden

A one dimensional stochastic exclusion process with two species of particles, $+$ and $-$, is studied where density of each species can fluctuate but the total particle density is conserved. From the exact stationary state weights we show…

Statistical Mechanics · Physics 2017-01-10 Urna Basu

A resistor-network picture of transitions is appropriate for the study of energy absorption by weakly chaotic or weakly interacting driven systems. Such "sparse" systems reach a novel non-equilibrium steady state (NESS) once coupled to a…

Quantum Physics · Physics 2011-03-21 Daniel Hurowitz , Doron Cohen

Biomolecular processes are typically modeled using chemical reaction networks coupled to infinitely large chemical reservoirs. A difference in chemical potential between these reservoirs can drive the system into a non-equilibrium steady…

Statistical Mechanics · Physics 2020-06-17 Jonas H. Fritz , Basile Nguyen , Udo Seifert

The effect of particle-nonconserving processes on the steady state of driven diffusive systems is studied within the context of a generalized ABC model. It is shown that in the limit of slow nonconserving processes, the large deviation…

Statistical Mechanics · Physics 2012-02-17 Or Cohen , David Mukamel

Statistical models provide a powerful and useful class of approximations for calculating reaction rates by bypassing the need for detailed, and often difficult, dynamical considerations. Such approaches invariably invoke specific…

Chemical Physics · Physics 2020-04-01 Sourav Karmakar , Pankaj Kumar Yadav , Srihari Keshavamurthy

A phase transition indicates a sudden change in the properties of a large system. For temperature-driven phase transitions this is related to non-analytic behavior of the free energy density at the critical temperature: The knowledge of the…

Statistical Mechanics · Physics 2015-03-20 Markus Heyl , Anatoli Polkovnikov , Stefan Kehrein
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