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The phenotypic plasticity of cancer cells has received special attention in recent years. Even though related models have been widely studied in terms of mathematical properties, a thorough statistical analysis on parameter estimation and…

Cell Behavior · Quantitative Biology 2017-12-05 Da Zhou , Shanjun Mao , Kaiyi Chen , Xiaofang Cao , Jie Hu

Disease mapping analyses the distribution of several disease outcomes within a territory. Primary goals include identifying areas with unexpected changes in mortality rates, studying the relation among multiple diseases, and dividing the…

Methodology · Statistics 2025-08-19 Andrea Sottosanti , Enrico Bovo , Pietro Belloni , Giovanna Boccuzzo

Improving health in the most disadvantaged populations requires reliable estimates of health and demographic indicators to inform policy and interventions. Low- and middle-income countries with the largest burden of disease and disability…

Methodology · Statistics 2025-11-21 Austin E Schumacher , Jon Wakefield

In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox…

Applications · Statistics 2019-11-05 Satabdi Saha , Duchwan Ryu , Nader Ebrahimi

The appropriateness of the Poisson model is frequently challenged when examining spatial count data marked by unbalanced distributions, over-dispersion, or under-dispersion. Moreover, traditional parametric models may inadequately capture…

Methodology · Statistics 2025-03-26 Mahsa Nadifar , Andriette Bekker , Mohammad Arashi , Abel Ramoelo

This paper proposes a new model-based approach to small area estimation of general finite-population parameters based on grouped data or frequency data, which is often available from sample surveys. Grouped data contains information on…

Methodology · Statistics 2019-09-20 Yuki Kawakubo , Genya Kobayashi

Model averaging techniques in the actuarial literature aim to forecast future longevity appropriately by combining forecasts derived from various models. This approach often yields more accurate predictions than those generated by a single…

Applications · Statistics 2025-10-28 Giovanna Bimonte , Maria Russolillo , Han Lin Shang , Yang Yang

Estimating health indicators for restricted sub-populations is a recurring challenge in epidemiology and public health. When survey data are used, Small Area Estimation (SAE) methods can improve precision by borrowing strength across…

Methodology · Statistics 2026-01-28 Aldo Gardini , Lorenzo Mori

We provide forecasts for mortality rates by using two different approaches. First we employ dynamic non-linear logistic models based on Heligman-Pollard formula. Second, we assume that the dynamics of the mortality rates can be modelled…

Applications · Statistics 2019-01-29 Angelos Alexopoulos , Petros Dellaportas , Jonathan J. Forster

This comment emphasizes the importance of model checking and model fitting when making inferences about finite population quantities. It also suggests the value of using unit level models when making inferences for small subpopulations,…

Methodology · Statistics 2011-08-22 J. Sedransk

In Official Statistics, interest for data integration has been increasingly growing, due to the need of extracting information from different sources. However, the effects of these procedures on the validity of the resulting statistical…

Small-area mortality estimation is inherently difficult, as random fluctuations from low death counts can obscure real geographic differences. We introduce a flexible model that borrows strength across age, space, and time to estimate…

Applications · Statistics 2025-11-25 Jacob Martin , Carlo Giovanni Camarda

Regional aggregates of health outcomes over delineated administrative units (e.g., states, counties, zip codes), or areal units, are widely used by epidemiologists to map mortality or incidence rates and capture geographic variation. To…

Methodology · Statistics 2022-05-03 Leiwen Gao , Sudipto Banerjee , Beate Ritz

This paper explores machine learning (ML) models for classifying lung cancer levels to improve diagnostic accuracy and prognosis. Through parameter tuning and rigorous evaluation, we assess various ML algorithms. Techniques like minimum…

Artificial Intelligence · Computer Science 2024-12-05 Mohsen Asghari Ilani , Saba Moftakhar Tehran , Ashkan Kavei , Hamed Alizadegan

Disease maps are an important tool in cancer epidemiology used for the analysis of geographical variations in disease rates and the investigation of environmental risk factors underlying spatial patterns. Cancer maps help epidemiologists…

Applications · Statistics 2020-12-08 Leiwen Gao , Sudipto Banerjee , Abhirup Datta

This research set out to explore and delineate spatial patterns and mortality distributions for various cancer types across U.S. states between 1999 and 2021. The aim was to uncover region-specific cancer burdens and inform geographically…

Applications · Statistics 2025-08-19 E. Kubuafor , D. Baidoo , A. Duah , R. Amevor , O. J. Okeke , D. Quaye , P. O. Appiah

Lung cancer (LC) is a leading cause of cancer-related mortality in the United States. Accurate prediction of LC mortality rates is crucial for guiding targeted interventions and addressing health disparities. Although traditional…

Machine Learning · Computer Science 2025-12-23 Soheil Hashtarkhani , Brianna M. White , Benyamin Hoseini , David L. Schwartz , Arash Shaban-Nejad

The gamma distribution is a useful model for small area prediction of a skewed response variable. We study the use of the gamma distribution for small area prediction. We emphasize a model, called the gamma-gamma model, in which the area…

Methodology · Statistics 2023-01-18 Yanghyeon Cho , Emily Berg

Accurate cancer risk estimation is crucial to clinical decision-making, such as identifying high-risk people for screening. However, most existing cancer risk models incorporate data from epidemiologic studies, which usually cannot…

Methodology · Statistics 2023-10-26 Lingxiao Wang , Yan Li , Barry Graubard , Hormuzd Katki

Fitting spatio-temporal models for areal data is crucial in many fields such as cancer epidemiology. However, when data sets are very large, many issues arise. The main objective of this paper is to propose a general procedure to analyze…

Methodology · Statistics 2023-02-06 E. Orozco-Acosta , A. Adin , M. D. Ugarte
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