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We introduce EVE (Elemental Variational Expanse), a variational distributional neuron formulated as a local probabilistic computational unit with an explicit prior, an amortized posterior, and unit-level variational regularization. In most…
Hearts subjected to volume overload (VO) are prone to detrimental anatomical and functional changes in response to elevated mechanical loading, ultimately leading to heart failure. Experimental findings now emphasize that organ-scale…
Models of cortical neuronal circuits commonly depend on inhibitory feedback to control gain, provide signal normalization, and to selectively amplify signals using winner-take-all (WTA) dynamics. Such models generally assume that excitatory…
Lifelong learning capabilities are crucial for artificial autonomous agents operating on real-world data, which is typically non-stationary and temporally correlated. In this work, we demonstrate that dynamically grown networks outperform…
Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the…
Growth of hard--rod monolayers via deposition is studied in a lattice model using rods with discrete orientations and in a continuum model with hard spherocylinders. The lattice model is treated with kinetic Monte Carlo simulations and…
A curious feature of organ and organoid morphogenesis is that in certain cases, spatial oscillations in the thickness of the growing "film" are out-of-phase with the deformation of the slower-growing "substrate," while in other cases, the…
A central and extensively debated question in glass physics concerns whether a single, growing lengthscale fundamentally controls glassy dynamics, particularly in systems lacking obvious structural motifs like the Kob Andersen binary…
Understanding the information processing roles of cortical circuits is an outstanding problem in neuroscience and artificial intelligence. The theoretical setting of Bayesian inference has been suggested as a framework for understanding…
Neuronal growth cones are the most sensitive amongst eukaryotic cells in responding to directional chemical cues. Although a dynamic microtubule cytoskeleton has been shown to be essential for growth cone turning, the precise nature of…
Understanding convergent learning -- the degree to which independently trained neural systems -- whether multiple artificial networks or brains and models -- arrive at similar internal representations -- is crucial for both neuroscience and…
Topographic maps are a brain structure connecting pre-synpatic and post-synaptic brain regions. Topographic development is dependent on Hebbian-based plasticity mechanisms working in conjunction with spontaneous patterns of neural activity…
Cortical activity in-vivo displays relaxational time scales much longer than the membrane time constant of the neurons or the deactivation time of ionotropic synaptic conductances. The mechanisms responsible for such slow dynamics are not…
Growth-elasticity is a powerful model framework for understanding complex shape development in soft biological tissues. At each instant, by mapping how continuum building blocks have grown geometrically and how they respond elastically to…
The cerebellum and cerebral cortex form tightly coupled circuits thought to support flexible and efficient temporal processing. How this interaction shapes cortical learning dynamics, and whether such heterogeneous modularity can benefit…
Vertically vibrated rod-shaped granular materials confined to quasi-2D containers self organize into distinct patterns. We find, consistent with theory and simulation, a density dependent isotropic-nematic transition. Along the walls, rods…
Cortical neurons emit seemingly erratic trains of action potentials or "spikes," and neural network dynamics emerge from the coordinated spiking activity within neural circuits. These rich dynamics manifest themselves in a variety of…
Self-organized bistability (SOB) is the counterpart of 'self-organized criticality' (SOC), for systems tuning themselves to the edge of bistability of a discontinuous phase transition, rather than to the critical point of a continuous one.…
The organization of neurons into functionally related assemblies is a fundamental feature of cortical networks, yet our understanding of how these assemblies maintain distinct identities while sharing members remains limited. Here we…
Spontaneously evolving living systems can be modelled as continuous-time dynamical systems (DSs), whose evolution rules are determined by their velocity vector fields. We point out that because of their architectural plasticity, biological…