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Microelectronic morphogenesis is the creation and maintenance of complex functional structures by microelectronic information within shape-changing materials. Only recently has in-built information technology begun to be used to reshape…

Robotics · Computer Science 2024-05-24 John S. McCaskill , Daniil Karnaushenko , Minshen Zhu , Oliver G. Schmidt

Cellular populations such as avascular tumors and microbial biofilms may "invade" or grow into surrounding populations. The invading population is often comprised of a heterogeneous mixture of cells with varying growth rates. The population…

Biological Physics · Physics 2025-12-05 Clarisa Castillo , Maxim O. Lavrentovich

Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…

Machine Learning · Computer Science 2025-02-04 Edwin D. de Jong , Eric Marcus , Jonas Teuwen

The conformational properties of flexible and semiflexible polymers exposed to active noise are studied theoretically. The noise may originate from the interaction of the polymer with surround- ing active (Brownian) particles or from the…

Soft Condensed Matter · Physics 2024-06-03 Thomas Eisenstecken , Gerhard Gompper , Roland G. Winkler

Magnetic moments near zigzag edges in graphene allow complex nanostructures with customised spin properties to be realised. However, computational costs restrict theoretical investigations to small or perfectly periodic structures. Here we…

Mesoscale and Nanoscale Physics · Physics 2022-09-14 Meriç E. Kucukbas , Seán McCann , Stephen R. Power

Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, multi-factorial models are commonly used to study morphogenesis. It is difficult to understand the relation between the uncertainty in the…

Cell Behavior · Quantitative Biology 2015-11-25 Sonja E. M. Boas , Maria I. Navarro Jimenez , Roeland M. H. Merks , Joke G. Blom

The spatial distribution of population and activities within urban areas, or urban form at the mesoscopic scale, is the outcome of multiple antagonist processes. We propose in this paper to benchmark different models of urban morphogenesis,…

Physics and Society · Physics 2020-09-01 Juste Raimbault

Molecular phenotypes are important links between genomic information and organismic functions, fitness, and evolution. Complex phenotypes, which are also called quantitative traits, often depend on multiple genomic loci. Their evolution…

Populations and Evolution · Quantitative Biology 2015-06-12 Armita Nourmohammad , Stephan Schiffels , Michael Laessig

To detect bias in face recognition networks, it can be useful to probe a network under test using samples in which only specific attributes vary in some controlled way. However, capturing a sufficiently large dataset with specific control…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Nataniel Ruiz , Barry-John Theobald , Anurag Ranjan , Ahmed Hussein Abdelaziz , Nicholas Apostoloff

The objective function of a matrix factorization model usually aims to minimize the average of a regression error contributed by each element. However, given the existence of stochastic noises, the implicit deviations of sample data from…

Machine Learning · Computer Science 2016-10-31 Guang-He Lee , Shao-Wen Yang , Shou-De Lin

Cell migration is crucial to many physiological and pathological processes. During migration, a cell adapts its morphology, including the overall morphology and nucleus morphology, in response to various cues in complex microenvironments,…

Biological Physics · Physics 2023-08-28 Yanping Liu , Yang Jiao , Qihui Fan , Xinwei Li , Zhichao Liu , Jun Hu , Jianwei Shuai , Liyu Liu , Zhangyong Li

Living tissues experience various external forces on cells, influencing their behaviour, physiology, shape, gene expression, and destiny through interactions with their environment. Despite much research done in this area, challenges remain…

Quantitative Methods · Quantitative Biology 2024-03-05 Akepogu Venkateshwarlu , Akshayveer , Sundeep Singh , Roderick Melnik

Embodiment co-design aims to optimize a robot's morphology and control policy simultaneously. While prior work has demonstrated its potential for generating environment-adaptive robots, this field still faces persistent challenges in…

Robotics · Computer Science 2025-03-04 Haofei Lu , Zhe Wu , Junliang Xing , Jianshu Li , Ruoyu Li , Zhe Li , Yuanchun Shi

Precise representations of 3D faces are beneficial to various computer vision and graphics applications. Due to the data discretization and model linearity, however, it remains challenging to capture accurate identity and expression clues…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Mingwu Zheng , Hongyu Yang , Di Huang , Liming Chen

Many biological systems regulate phenotypic heterogeneity as a fitness-maximising strategy in uncertain and dynamic environments. Analysis of such strategies is typically confined both to a discrete set of environmental conditions, and to a…

Populations and Evolution · Quantitative Biology 2025-07-02 Alexander P Browning , Sara Hamis

Pluripotent embryonic stem cells are of paramount importance for biomedical research thanks to their innate ability for self-renewal and differentiation into all major cell lines. The fateful decision to exit or remain in the pluripotent…

Molecular Networks · Quantitative Biology 2018-07-04 Yen Ting Lin , Peter G. Hufton , Esther J. Lee , Davit A. Potoyan

Fitting parametric models of human bodies, hands or faces to sparse input signals in an accurate, robust, and fast manner has the promise of significantly improving immersion in AR and VR scenarios. A common first step in systems that…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Vasileios Choutas , Federica Bogo , Jingjing Shen , Julien Valentin

Transformer models have become the dominant backbone for sequence modeling, leveraging self-attention to produce contextualized token representations. These are typically aggregated into fixed-size vectors via pooling operations for…

Machine Learning · Computer Science 2025-10-07 Sofiane Ennadir , Levente Zólyomi , Oleg Smirnov , Tianze Wang , John Pertoft , Filip Cornell , Lele Cao

Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modelling this process can provide novel insights into development and the principles that orchestrate the…

Tissues and Organs · Quantitative Biology 2018-06-13 M. D. Peters , L. D. Wittwer , A. Stopka , D. Barac , C. Lang , D. Iber

Biophotonic signaling via axons has been proposed as a potential mode of neural communication, where information might be encoded not only in photon number and wavelength but also in polarization. Although earlier computational studies have…

Biological Physics · Physics 2026-05-18 Ethan Davies , Rishabh , Christoph Simon