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Evolving morphologies and controllers of robots simultaneously leads to a problem: Even if the parents have well-matching bodies and brains, the stochastic recombination can break this match and cause a body-brain mismatch in their…

Robotics · Computer Science 2022-03-09 Fuda van Diggelen , Eliseo Ferrante , A. E. Eiben

Epigenetics is a driving force of important and ubiquitous phenomena in nature such as cell differentiation or even metamorphosis. Oppositely to its widespread role, understanding the biophysical principles that allow epigenetics to control…

Soft Condensed Matter · Physics 2020-01-08 Davide Colì , Davide Michieletto , Davide Marenduzzo , Enzo Orlandini

The mechanism by which cells measure the dimension of the organ in which they are embedded, and slow down their growth when the final size is reached, is a long-standing problem of developmental biology. The role of mechanics in this…

Biological Physics · Physics 2023-07-19 Alexander Erlich , Pierre Recho

To perform recognition, molecules must locate and specifically bind their targets within a noisy biochemical environment with many look-alikes. Molecular recognition processes, especially the induced-fit mechanism, are known to involve…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

The first cell fate decisions in the developing fly embryo are made very rapidly : hunchback genes decide in a few minutes whether a given nucleus follows the anterior or the posterior developmental blueprint by reading out the positional…

Molecular Networks · Quantitative Biology 2019-06-24 Jonathan Desponds , Massimo Vergassola , Aleksandra M. Walczak

Soft robotics holds transformative potential for enabling adaptive and adaptable systems in dynamic environments. However, the interplay between morphological and control complexities and their collective impact on task performance remains…

Robotics · Computer Science 2025-03-27 Yue Xie , Kai-fung Chu , Xing Wang , Fumiya Iida

Motivation: Spatial pattern formation of the primary anterior-posterior morphogenetic gradient of the transcription factor Bicoid (Bcd) has been studied experimentally and computationally for many years. Bcd specifies positional information…

Quantitative Methods · Quantitative Biology 2019-06-27 Theodore Alexandrov , Nina Golyandina , David Holloway , Alex Shlemov , Alexander Spirov

Recent years have brought great advances into solving morphological tasks, mostly due to powerful neural models applied to various tasks as (re)inflection and analysis. Yet, such morphological tasks cannot be considered solved, especially…

Computation and Language · Computer Science 2023-06-23 David Guriel , Omer Goldman , Reut Tsarfaty

Ellipse and ellipsoid fitting has been extensively researched and widely applied. Although traditional fitting methods provide accurate estimation of ellipse parameters in the low-noise case, their performance is compromised when the noise…

Methodology · Statistics 2009-12-10 Jieqi Yu , Sanjeev R. Kulkarni , H. Vincent Poor

Contemporary deep learning models effectively handle languages with diverse morphology despite not being directly integrated into them. Morphology and word order are closely linked, with the latter incorporated into transformer-based models…

Computation and Language · Computer Science 2024-05-31 Poulami Ghosh , Shikhar Vashishth , Raj Dabre , Pushpak Bhattacharyya

Morphogenesis is the biological process that causes the emergence and changes of patterns (tissues and organs) in living organisms. It is a robust, self-organising mechanism, governed by Genetic Regulatory Networks (GRN), that hasn't been…

Molecular Networks · Quantitative Biology 2026-03-17 Yuriria Cortes-Poza , J. Rogelio Perez-Buendia

We discuss the formation of graded morphogen profiles in a cell layer by nonlinear transport phenomena, important for patterning developing organisms. We focus on a process termed transcytosis, where morphogen transport results from binding…

Other Quantitative Biology · Quantitative Biology 2007-05-23 T. Bollenbach , K. Kruse , P. Pantazis , M. González-Gaitán , F. Jülicher

Modeling the spontaneous evolution of morphology in natural systems and its preservation by proportionate growth remains a major scientific challenge. Yet, it is conceivable that if the basic mechanisms of growth and the coupled kinetic…

Soft Condensed Matter · Physics 2020-12-30 Virginia von Streng , Rami Abi-Akl , Bianca Giovanardi , Tal Cohen

A model of morphogenesis is proposed based on seven explicit postulates. The mathematical import and biological significance of the postulates are explored and discussed.

Quantitative Methods · Quantitative Biology 2018-02-21 Andrey Minarsky , Nadya Morozova , Robert Penner , Christophe Soule

Birth weight serves as a fundamental indicator of neonatal health, closely linked to both early medical interventions and long-term developmental risks. Traditional predictive models, often constrained by limited feature selection and…

The extent to which individual language characteristics influence tokenization and language modeling is an open question. Differences in morphological systems have been suggested as both unimportant and crucial to consider (Cotterell et…

Computation and Language · Computer Science 2025-11-04 Wessel Poelman , Thomas Bauwens , Miryam de Lhoneux

A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How branching morphogenesis can create epithelial architectures of very…

Tissues and Organs · Quantitative Biology 2021-03-02 Christine Lang , Lisa Conrad , Dagmar Iber

Brain morphology is shaped by genetic and mechanical factors and is linked to biological development and diseases. Its fractal-like features, regional anisotropy, and complex curvature distributions hinder quantitative insights in medical…

Neurons and Cognition · Quantitative Biology 2025-09-09 Yingjie Zhao , Yicheng Song , Fan Xu , Zhiping Xu

We study by simulation the effect of the diffusive motion of repressor molecules on the noise in mRNA and protein levels in the case of a repressed gene. We find that spatial fluctuations due to diffusion can drastically enhance the noise…

Molecular Networks · Quantitative Biology 2007-05-23 Jeroen S. van Zon , Marco J. Morelli , Sorin Tanase-Nicola , Pieter Rein ten Wolde

A model to describe the arising of new structures in an initial homogeneous biological system is proposed. The essay is motivated by the intention to work on a non-equilibrium situation grouping together several mechanisms and processes as:…

Biological Physics · Physics 2007-05-23 P. C. T. Dajello , P. R. Hauser