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Identifying latent structure in large data matrices is essential for exploring biological processes. Here, we consider recovering gene co-expression networks from gene expression data, where each network encodes relationships between genes…

Methodology · Statistics 2014-11-10 Chuan Gao , Shiwen Zhao , Ian C. McDowell , Christopher D. Brown , Barbara E. Engelhardt

Robust cardiac image segmentation is still an open challenge due to the inability of the existing methods to achieve satisfactory performance on unseen data of different domains. Since the acquisition and annotation of medical data are…

Image and Video Processing · Electrical Eng. & Systems 2020-08-27 Xiao Liu , Spyridon Thermos , Agisilaos Chartsias , Alison O'Neil , Sotirios A. Tsaftaris

Multivariate time-series have become abundant in recent years, as many data-acquisition systems record information through multiple sensors simultaneously. In this paper, we assume the variables pertain to some geometry and present an…

Machine Learning · Statistics 2022-01-24 Tal Shnitzer , Hau-Tieng Wu , Ronen Talmon

We study the asymptotic behavior of multiscale stochastic spatial gene networks. Multiscaling takes into account the difference of abundance between molecules , and captures the dynamic of rare species at a mesoscopic level. We introduce an…

Analysis of PDEs · Mathematics 2017-11-17 Arnaud Debussche , Mac Jugal Nguepedja Nankep

We present a geometric framework for regression on structured high-dimensional data that shifts the analysis from the ambient space to a geometric object capturing the data's intrinsic structure. The method addresses a fundamental challenge…

Methodology · Statistics 2025-11-07 Pawel Gajer , Jacques Ravel

Automated polyp segmentation technology plays an important role in diagnosing intestinal diseases, such as tumors and precancerous lesions. Previous works have typically trained convolution-based U-Net or Transformer-based neural network…

Image and Video Processing · Electrical Eng. & Systems 2022-11-18 Lei Zhou

Data derived from remote sensing or numerical simulations often have a regular gridded structure and are large in volume, making it challenging to find accurate spatial models that can fill in missing grid cells or simulate the process…

Machine Learning · Statistics 2025-05-07 Sweta Rai , Douglas W. Nychka , Soutir Bandyopadhyay

Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large…

Molecular Networks · Quantitative Biology 2018-06-29 Marieke Lydia Kuijjer , Matthew Tung , GuoCheng Yuan , John Quackenbush , Kimberly Glass

We introduce a novel longitudinal mixed model for analyzing complex multidimensional functional data, addressing challenges such as high-resolution, structural complexities, and computational demands. Our approach integrates dimension…

Methodology · Statistics 2026-02-16 Arkaprava Roy , Abhra Sarkar

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

Satellite data of atmospheric pollutants are often available only at coarse spatial resolution, limiting their applicability in local-scale environmental analysis and decision-making. Spatial downscaling methods aim to transform the coarse…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Mika Sipilä , Sabrina Maggio , Sandra De Iaco , Klaus Nordhausen , Monica Palma , Sara Taskinen

In this work we propose a novel approach for modeling spatio-temporal data characterized by group structures. In particular, we extend classical mixed effect regression models by introducing a space-time nonparametric component, regularized…

Methodology · Statistics 2025-11-18 Marco F. De Sanctis , Eleonora Arnone , Francesca Ieva , Laura M. Sangalli

In this study, a novel method of data augmentation has been presented for the segmentation of placental histological images when the labeled data are scarce. This method generates new realizations of the placenta intervillous morphology…

Image and Video Processing · Electrical Eng. & Systems 2022-10-10 Arash Rabbani , Masoud Babaei , Masoumeh Gharib

Binary trait data record the presence or absence of distinguishing traits in individuals. We treat the problem of estimating ancestral trees with time depth from binary trait data. Simple analysis of such data is problematic. Each homology…

Methodology · Statistics 2009-08-31 Geoff K. Nicholls , Russell D. Gray

Surrogate models driven by sizeable datasets and scientific machine-learning methods have emerged as an attractive microstructure simulation tool with the potential to deliver predictive microstructure evolution dynamics with huge savings…

Materials Science · Physics 2024-01-22 Shaoxun Fan , Andrew L. Hitt , Ming Tang , Babak Sadigh , Fei Zhou

Reconstructing interactions from observational data is a critical need for investigating natural biological networks, wherein network dimensionality (i.e. number of interacting components) is usually high and interactions are time-varying.…

Populations and Evolution · Quantitative Biology 2021-02-09 Chun-Wei Chang , Takeshi Miki , Masayuki Ushio , Hsiao-Pei Lu , Fuh-Kwo Shiah , Chih-hao Hsieh

More than 80% of today's data is unstructured in nature, and these unstructured datasets evolve over time. A large part of these datasets are text documents generated by media outlets, scholarly articles in digital libraries, findings from…

Computation and Language · Computer Science 2019-03-21 Roberto Camacho Barranco , Raimundo F. Dos Santos , M. Shahriar Hossain

The availability of massive earth observing satellite data provide huge opportunities for land use and land cover mapping. However, such mapping effort is challenging due to the existence of various land cover classes, noisy data, and the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Rahul Ghosh , Praveen Ravirathinam , Xiaowei Jia , Chenxi Lin , Zhenong Jin , Vipin Kumar

A new algorithm is developed to jointly recover a temporal sequence of images from noisy and under-sampled Fourier data. Specifically, we consider the case where each data set is missing vital information that prevents its (individual)…

Numerical Analysis · Mathematics 2022-05-13 Yao Xiao , Jan Glaubitz , Anne Gelb , Guohui Song

This paper considers generalised network, intended as networks where (a) the edges connecting the nodes are nonlinear, and (b) stochastic processes are continuously indexed over both vertices and edges. Such topological structures are…

Social and Information Networks · Computer Science 2023-09-29 Tobia Filosi , Claudio Agostinelli , Emilio Porcu