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Biological nanomachines are nanometer-size macromolecular complexes that catalyze chemical reactions in the presence of substrate molecules. The catalytic functions carried out by such nanomachines in the cytoplasm, and biological membranes…

Soft Condensed Matter · Physics 2022-11-22 Yuto Hosaka , Shigeyuki Komura

The Neutron Transport Equation (NTE) describes the flux of neutrons through inhomogeneous fissile medium. Whilst well treated in the nuclear physics literature (cf. [9, 27]), the NTE has had a somewhat scattered treatment in mathematical…

Probability · Mathematics 2019-06-05 Alex M. G. Cox , Simon C. Harris , Emma Horton , Andreas E. Kyprianou

Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez

A method is presented which allows one to introduce collective coordinates self-consistently, in distinction to the Caldeira-Leggett model. It is demonstrated how the partition function Z for the total nuclear system can be calculated to…

Nuclear Theory · Physics 2009-11-10 Christian Rummel , Helmut Hofmann

Electroporation method is a useful tool for delivering drugs into various diseased tissues in the human body. As a result of an applied electric field, drug particles enter the intracellular compartment through the temporarily permeabilized…

Tissues and Organs · Quantitative Biology 2022-08-10 Nilay Mondal , K. S. Yadav , D. C. Dalal

A living cell's interior is one of the most complex and intrinsically dynamic systems, providing an elaborate interplay between cytosolic crowding and ATP-driven motion, which controls cellular functionality. Here, we investigated two…

Biological Physics · Physics 2019-11-14 P. Witzel , M. Götz , Y. Lanoiselée , T. Franosch , D. S. Grebenkov , D. Heinrich

Transport equations for autonomous driven Fermionic quantum systems are derived with the help of statistical assumptions and of the Markov approximation. The statistical assumptions hold if the system consists of subsystems within which…

Nuclear Theory · Physics 2022-04-20 Hans A. Weidenmüller

Due to the stochastic nature of biochemical processes, the copy number of any given type of molecule inside a living cell often exhibits large temporal fluctuations. Here, we develop analytic methods to investigate how the noise arising…

Subcellular Processes · Quantitative Biology 2015-05-13 Li-ping Xiong , Yu-qiang Ma , Lei-Han Tang

We analyze the equilibration process between two either fermionic or bosonic reservoirs containing ultracold atoms with a fixed total number of particles that are weakly connected via a few-level quantum system. We allow for both the…

Drug delivery through electroporation could be highly beneficial for the treatment of different types of diseased tissues within the human body. In this work, a mathematical model of reversible tissue electroporation is presented for…

Functional Analysis · Mathematics 2022-08-03 Nilay Mondal , D. C. Dalal

Energy transport is of central importance in understanding a wide variety of transitions of physical states in nature. Recently, the coherence and noise have been identified for their existence and key roles in energy transport processes,…

The entropy production rate of cancer cell is always higher than healthy cell under the case of no external field applied. Different entropy production between two kinds of cells determines the direction of entropy flow among cells. The…

Cell Behavior · Quantitative Biology 2009-11-13 Liaofu Luo

Partitioning and transport of water and small solutes into and through nanopores is important to a variety of chemical and biological processes and applications. Here we study the partitioning of positive ions of increasing size into the…

Chemical Physics · Physics 2007-05-23 Lu Yang , Shekhar Garde

A chloroplast is a subcellular organelle of photosynthesis in plant and algal cells. A chloroplast genome encodes proteins of the photosynthetic electron transport chain and ribosomal proteins required to express them. Chloroplast-encoded…

Molecular Networks · Quantitative Biology 2025-12-13 John F. Allen

Living systems relay information across membrane interfaces to coordinate compartment functions. We identify a physical mechanism for selective information transmission that arises from the sigmoidal response of surface-bound particle…

Statistical Mechanics · Physics 2025-12-29 Jenna Elliott , Hiral Shah , Roman Belousov , Gautam Dey , Anna Erzberger

We survey some recent accumulated body of works on hyperfine-mediated transport in a confined one-dimensional channel, realized typically by electrostatic gating. Our review begins with how the spin-polarized edge current can be used as a…

Mesoscale and Nanoscale Physics · Physics 2021-10-13 M. H. Fauzi , Y. Hirayama

Translation is one of the main steps in the synthesis of proteins. It consists of ribosomes that translate sequences of nucleotides encoded on mRNA into polypeptide sequences of amino acids. Ribosomes bound to mRNA move unidirectionally,…

Subcellular Processes · Quantitative Biology 2022-01-19 Olivier Dauloudet , Izaak Neri , Jean-Charles Walter , Jérôme Dorignac , Frédéric Geniet , Andrea Parmeggiani

We introduce the totally asymmetric exclusion process with Langmuir kinetics (TASEP-LK) on a network as a microscopic model for active motor protein transport on the cytoskeleton, immersed in the diffusive cytoplasm. We discuss how the…

Statistical Mechanics · Physics 2013-03-01 I. Neri , N. Kern , A. Parmeggiani

The ribosome is one of the largest and most complex macromolecular machines in living cells. It polymerizes a protein in a step-by-step manner as directed by the corresponding nucleotide sequence on the template messenger RNA (mRNA) and…

Statistical Mechanics · Physics 2020-03-11 Annwesha Dutta , Gunter M Schütz , Debashish Chowdhury

We present a new modeling approach for G protein coupled receptors signaling systems, that take into account the compartmentalization of receptors and their effectors, both at plasma membrane and in dynamic intra-cellular vesicles called…

Analysis of PDEs · Mathematics 2023-05-23 Claire Alamichel , Juan Calvo , Erwan Hingant , Saoussen Latrach , Nathan Quiblier , Romain Yvinec