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Understanding the mechanism of protein secondary structure formation is an essential part of protein-folding puzzle. Here we describe a simple model for the formation of the $\beta$-hairpin, motivated by the fact that folding of a…

Soft Condensed Matter · Physics 2009-10-31 Chinlin Guo , Herbert Levine , David Kessler

A rectangular thin elastic sheet is deformed by forcing a contact between two points at the middle of its length. A transition to buckling with stress focusing is reported for the sheets sufficiently narrow with a critical width…

Soft Condensed Matter · Physics 2021-07-14 Thomas Barois , Ilyes Jalisse , Loïc Tadrist , Emmanuel Virot

Membrane neck formation is essential for scission, which, as recent experiments on tubules have demonstrated, can be location dependent. The diversity of biological machinery that can constrict a neck such as dynamin, actin, ESCRTs and BAR…

Biological Physics · Physics 2019-12-11 Ritvik Vasan , Shiva Rudraraju , Matthew Akamatsu , Krishna Garikipati , Padmini Rangamani

Theoretical studies of stretching proteins with slipknots reveal a surprising growth of their unfolding times when the stretching force crosses an intermediate threshold. This behavior arises as a consequence of the existence of alternative…

Biomolecules · Quantitative Biology 2010-01-05 Joanna I. Sułkowska , Piotr Sułkowski , José N. Onuchic

The dynamic behavior of a partially wetting polymer droplet driven over a nanostructured interface is studied using molecular dynamics simulations. We consider the bead-spring model to represent a polymeric liquid that partially wets a…

Soft Condensed Matter · Physics 2020-06-17 Anish Thomas , Nikolai V. Priezjev

We develop a mathematical model to capture the web dynamics of slingshot spiders (Araneae: Theridiosomatidae), which utilize a tension line to deform their orb webs into conical springs to hunt flying insects. Slingshot spiders are…

A plethora of natural and industrial shear-driven granular flows exhibit particle-size segregation. Its occurrence is commonly attributed to two primary mechanisms: kinetic sieving and squeeze expulsion. While kinetic sieving is relatively…

Soft Condensed Matter · Physics 2026-04-08 Alexander J. Navarrete , Leonardo Gordillo , Tomás Trewhela

In this paper, the scattering/transmission inside a step-modulated subwavelength metal slit is investigated in detail. We firstly investigate the scattering in a junction structure by two types of structural changes. The variation of…

Optics · Physics 2015-05-30 Chao Li , Yun-Song Zhou , Huai-Yu Wang , Jian-Hong Guo

A recent survey of 17 134 proteins has identified a new class of proteins which are expected to yield stretching induced force-peaks in the range of 1 nN. Such high force peaks should be due to forcing of a slip-loop through a cystine ring,…

Biomolecules · Quantitative Biology 2015-05-27 Lukasz Peplowski , Mateusz Sikora , Wieslaw Nowak , Marek Cieplak

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

Cell Behavior · Quantitative Biology 2019-09-04 Carina M. Dunlop

A recent report on successful employment of the grain boundary strengthening to design extraordinarily damage-tolerant architected materials (i.e. meta-crystals) necessitates fundamental studies to understand the underlying mechanisms…

Materials Science · Physics 2020-11-05 Chen Liu , Jedsada Lertthanasarn , Minh-Son Pham

The kinetics of dislocations is studied with computer simulation at loadings of different intensity. It is established that the dislocations have a few different structural states. The dislocations "with the micropore" play important role…

Materials Science · Physics 2007-05-23 L. S. Metlov

We review the physical properties of macromolecular networks, consisting of semiflexible polymers such as actin. We start by giving a theoretical analysis of the conformational statistics and mechanical response of single filaments.…

Soft Condensed Matter · Physics 2008-02-03 Erwin Frey , Klaus Kroy , Jan Wilhelm , Erich Sackmann

In many adult tissues, stem cells and differentiated cells are not homogeneously distributed : stem cells are arranged in periodic "niches", and differentiated cells are constantly produced and migrate out of these niches. In this article,…

Biological Physics · Physics 2016-03-23 Edouard Hannezo , Alice Coucke , Jean-François Joanny

We study the shapes of human red blood cells using continuum mechanics. In particular, we model the crenated, echinocytic shapes and show how they may arise from a competition between the bending energy of the plasma membrane and the…

Soft Condensed Matter · Physics 2009-11-07 Ranjan Mukhopadhyay , Gerald H. W. Lim , Michael Wortis

Cracking and peeling of a layer of clay on desiccation has been simulated using a spring model. A vertical section through the layer with finite thickness is represented by a rectangular array of nodes connected by linear springs on a…

Soft Condensed Matter · Physics 2009-11-13 Supti Sadhukhan , Janett Prehl , Peter Blaudeck , K. H. Hoffmann , Tapati Dutta , Sujata Tarafdar

Strain hardening is a key feature observed in many rocks deformed in the so-called ``semi-brittle'' regime, where both crystal plastic and brittle deformation mechanisms operate. Dislocation storage has long been recognised as a major…

Geophysics · Physics 2025-02-14 Nicolas Brantut

When humidified at different moisture conditions, restrained spider silk fibers can exhibit a very high supercontraction phenomenon. The hydration water molecules induce a Hydrogen-bonds disruption process that, due to entropic effects,…

Soft Condensed Matter · Physics 2023-03-27 Vincenzo Fazio , Nicola Maria Pugno , Giuseppe Puglisi

Differential shrinkage in particulate quasi-brittle materials causes microcracking which reduces durability in these materials by increasing their mass transport properties. A hydro-mechanical three-dimensional periodic network approach was…

Materials Science · Physics 2017-10-13 Ignatios Athanasiadis , Simon J. Wheeler , Peter Grassl

Simple expressions for the bending and the base-stacking energy of double-stranded semiflexible biopolymers (such as DNA and actin) are derived. The distribution of the folding angle between the two strands is obtained by solving a…

Soft Condensed Matter · Physics 2009-10-31 Zhou Haijun , Ou-Yang Zhong-can
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