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The human brain is a complex system that is fascinating scientists since a long time. Its remarkable capabilities include categorization of concepts, retrieval of memories and creative generation of new examples. At the same time, modern…

Disordered Systems and Neural Networks · Physics 2024-10-10 Enrico Ventura

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

Neurons and Cognition · Quantitative Biology 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung

The new era of artificial intelligence demands large-scale ultrafast hardware for machine learning. Optical artificial neural networks process classical and quantum information at the speed of light, and are compatible with silicon…

Medical Physics · Physics 2018-12-24 D. Pierangeli , V. Palmieri , G. Marcucci , C. Moriconi , G. Perini , M. De Spirito , M. Papi , C. Conti

Understanding protein structure-function relationships is a key challenge in computational biology, with applications across the biotechnology and pharmaceutical industries. While it is known that protein structure directly impacts protein…

Biomolecules · Quantitative Biology 2020-11-02 Nicolas Swenson , Aditi S. Krishnapriyan , Aydin Buluc , Dmitriy Morozov , Katherine Yelick

In this paper, the efficient hinging hyperplanes (EHH) neural network is proposed based on the model of hinging hyperplanes (HH). The EHH neural network is a distributed representation, the training of which involves solving several convex…

Systems and Control · Computer Science 2019-11-28 Jun Xu , Qinghua Tao , Zhen Li , Xiangming Xi , Johan A. K. Suykens , Shuning Wang

We introduce a new procedure for training of artificial neural networks by using the approximation of an objective function by arithmetic mean of an ensemble of selected randomly generated neural networks, and apply this procedure to the…

Neural and Evolutionary Computing · Computer Science 2012-02-21 S. V. Kozyrev

The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…

Machine Learning · Computer Science 2024-09-27 Jacobo Ruiz , Manas Gupta

Over 30 papers have proposed to use convolutional neural network (CNN) for AD classification from anatomical MRI. However, the classification performance is difficult to compare across studies due to variations in components such as…

We describe a new algorithm for learning multi-class neural-network models from large-scale clinical electroencephalograms (EEGs). This algorithm trains hidden neurons separately to classify all the pairs of classes. To find best pairwise…

Neural and Evolutionary Computing · Computer Science 2016-08-31 Vitaly Schetinin , Joachim Schult , Burkhart Scheidt , Valery Kuriakin

Meta-learning consists in learning learning algorithms. We use a Long Short Term Memory (LSTM) based network to learn to compute on-line updates of the parameters of another neural network. These parameters are stored in the cell state of…

Machine Learning · Computer Science 2016-10-20 Tom Bosc

The Recurrent Neural Networks and their variants have shown promising performances in sequence modeling tasks such as Natural Language Processing. These models, however, turn out to be impractical and difficult to train when exposed to very…

Computer Vision and Pattern Recognition · Computer Science 2017-07-07 Yinchong Yang , Denis Krompass , Volker Tresp

This work presents a multitemporal class-driven hierarchical Residual Neural Network (ResNet) designed for modelling the classification of Time Series (TS) of multispectral images at different semantical class levels. The architecture…

Computer Vision and Pattern Recognition · Computer Science 2025-10-10 Giulio Weikmann , Gianmarco Perantoni , Lorenzo Bruzzone

In EMG based pattern recognition (EMG-PR), deep learning-based techniques have become more prominent for their self-regulating capability to extract discriminant features from large data-sets. Moreover, the performance of traditional…

Signal Processing · Electrical Eng. & Systems 2021-06-14 Sidharth Pancholi , Amit M. Joshi , Deepak Joshi

This research is to search for alternatives to the resolution of complex medical diagnosis where human knowledge should be apprehended in a general fashion. Successful application examples show that human diagnostic capabilities are…

Neural and Evolutionary Computing · Computer Science 2010-09-28 Abu Bakar Siddiquee , Md. Ehsanul Hoque Mazumder , S. M. Kamruzzaman

Retrieval, the initial stage of a recommendation system, is tasked with down-selecting items from a pool of tens of millions of candidates to a few thousands. Embedding Based Retrieval (EBR) has been a typical choice for this problem,…

Understanding and leveraging the 3D structures of proteins is central to a variety of biological and drug discovery tasks. While deep learning has been applied successfully for structure-based protein function prediction tasks, current…

Machine Learning · Computer Science 2024-04-03 Rong Han , Wenbing Huang , Lingxiao Luo , Xinyan Han , Jiaming Shen , Zhiqiang Zhang , Jun Zhou , Ting Chen

Current protein forcefields like the ones seen in CHARMM or Xplor-NIH have many terms that include bonded and non-bonded terms. Yet the forcefields do not take into account the use of hydrogen bonds which are important for secondary…

Biomolecules · Quantitative Biology 2020-03-12 Timothy Matthew Fawcett , Stephanie Irausquin , Mikhail Simin , Homayoun Valafar

Hierarchical knowledge structures are ubiquitous across real-world domains and play a vital role in organizing information from coarse to fine semantic levels. While such structures have been widely used in taxonomy systems, biomedical…

Machine Learning · Computer Science 2026-03-10 Yunhui Liu , Yongchao Liu , Yinfeng Chen , Chuntao Hong , Tao Zheng , Tieke He

For many segmentation tasks, especially for the biomedical image, the topological prior is vital information which is useful to exploit. The containment/nesting is a typical inter-class geometric relationship. In the MICCAI Brain tumor…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 Xiaobin Hu , Hongwei Li , Yu Zhao , Chao Dong , Bjoern H. Menze , Marie Piraud

In this study, we propose HOPER (HOlistic ProtEin Representation), a novel multimodal learning framework designed to enhance protein function prediction (PFP) in low-data settings. The challenge of predicting protein functions is compounded…

Biomolecules · Quantitative Biology 2024-12-18 Serbülent Ünsal , Sinem Özdemir , Bünyamin Kasap , M. Erşan Kalaycı , Kemal Turhan , Tunca Doğan , Aybar C. Acar