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Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Achieving complete reproducibility in science, particularly in research fields such as biodiversity, is challenging due to analytical choices, bias and interpretation. Here, we examine examples of reproducibility in biological systematics,…

Other Quantitative Biology · Quantitative Biology 2025-08-01 Charles Morphy D. Santos , Luciana Campos Paulino , Michaella P. Andrade , Gabriel Tognella-Poccia , João Paulo Gois

Scientific data governance should prioritize maximizing the utility of data throughout the research lifecycle. Research software systems that enable analysis reproducibility inform data governance policies and assist administrators in…

Overall, the two main contributions of this work include the application of sentence simplification to association extraction as described above, and the use of distributional semantics for concept extraction. The proposed work on concept…

Computation and Language · Computer Science 2011-09-13 Siddhartha Jonnalagadda

Deep learning, which is especially formidable in handling big data, has achieved great success in various fields, including bioinformatics. With the advances of the big data era in biology, it is foreseeable that deep learning will become…

Quantitative Methods · Quantitative Biology 2019-03-04 Yu Li , Chao Huang , Lizhong Ding , Zhongxiao Li , Yijie Pan , Xin Gao

The most exciting challenge for CRIS is to create a service for research information which should be wide-spread, distributed and actual like Google, but at the same time structured, trusted, with a complex search and navigation similar to…

Networking and Internet Architecture · Computer Science 2007-05-23 A. Lopatenko

There is significant interest in using existing repositories of biological entities, relationships, and models to automate biological model assembly and extension. Current methods aggregate human-curated biological information into…

Molecular Networks · Quantitative Biology 2023-01-30 Adam A. Butchy , Cheryl A. Telmer , Natasa Miskov-Zivanov

A primary motivation for our research in Digital Ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

Neural and Evolutionary Computing · Computer Science 2016-11-18 G. Briscoe , S. Sadedin , G. Paperin

We describe the current state and future plans for a set of tools for scientific data management (SDM) designed to support scientific transparency and reproducible research. SDM has been in active use at our MRI Center for more than two…

Quantitative Methods · Quantitative Biology 2015-02-25 B. A. Wandell , A. Rokem , L. M. Perry , G. Schaefer , R. F. Dougherty

In recent years, there has been an increased focus on early detection, prevention, and prediction of diseases. This, together with advances in sensor technology and the Internet of Things, has led to accelerated efforts in the development…

Artificial Intelligence · Computer Science 2025-09-23 Mbithe Nzomo , Deshendran Moodley

DNA sequence analysis is fundamental to life science research. The rapid development of next generation sequencing (NGS) technologies, and the richness and diversity of applications it makes feasible, have created an enormous gulf between…

Computational Engineering, Finance, and Science · Computer Science 2013-10-29 Shel Swenson , Yogesh Simmhan , Viktor Prasanna , Manish Parashar , Jason Riedy , David Bader , Richard Vuduc

In cyber-physical convergence scenarios information flows seamlessly between the physical and the cyber worlds. Here, users' mobile devices represent a natural bridge through which users process acquired information and perform actions. The…

Networking and Internet Architecture · Computer Science 2022-06-06 Matteo Mordacchini , Lorenzo Valerio , Marco Conti , Andrea Passarella

Quantum technologies leverage the laws of quantum physics to achieve performance advantages in applications ranging from computing to communications and sensing. They have been proposed to have a range of applications in biological science.…

Quantum Physics · Physics 2021-11-04 Nicolas P. Mauranyapin , Alex Terrason , Warwick P. Bowen

Research organisms provide invaluable insights into human biology and diseases, serving as essential tools for functional experiments, disease modeling, and drug testing. However, evolutionary divergence between humans and research…

Genomics · Quantitative Biology 2025-11-05 Hao Yuan , Christopher A. Mancuso , Kayla Johnson , Ingo Braasch , Arjun Krishnan

Computerization of research activities led to the creation of large specialized information resources, platforms, services and software to support scientific research. However, their shortcomings do not allow to fully realizing the…

Digital Libraries · Computer Science 2015-04-21 Dmitry Prokudin

The recent efforts in automation of machine learning or data science has achieved success in various tasks such as hyper-parameter optimization or model selection. However, key areas such as utilizing domain knowledge and data semantics are…

Artificial Intelligence · Computer Science 2023-03-03 Udayan Khurana , Kavitha Srinivas , Sainyam Galhotra , Horst Samulowitz

The following is an outline of possible strategies in using semantic web techniques and math with regard to environmental issues. The article uses concrete examples and applications and provides partially a rather basic treatment of…

Digital Libraries · Computer Science 2012-09-11 Nadja Kutz

Semantic Web is, without a doubt, gaining momentum in both industry and academia. The word "Semantic" refers to "meaning" - a semantic web is a web of meaning. In this fast changing and result oriented practical world, gone are the days…

Information Retrieval · Computer Science 2015-03-17 Siddharth Gupta , Narina Thakur

This paper surveys foundation models for AI-enabled biological design, focusing on recent developments in applying large-scale, self-supervised models to tasks such as protein engineering, small molecule design, and genomic sequence design.…

Artificial Intelligence · Computer Science 2025-05-20 Asher Moldwin , Amarda Shehu

A primary motivation for our research in digital ecosystems is the desire to exploit the self-organising properties of biological ecosystems. Ecosystems are thought to be robust, scalable architectures that can automatically solve complex,…

Neural and Evolutionary Computing · Computer Science 2009-10-06 G. Briscoe , P. De Wilde