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Computing in the life sciences has undergone a transformative evolution, from early computational models in the 1950s to the applications of artificial intelligence (AI) and machine learning (ML) seen today. This paper highlights key…

Other Quantitative Biology · Quantitative Biology 2024-06-21 Samuel A. Donkor , Matthew E. Walsh , Alexander J. Titus

Semantic web technologies represent much richer forms of relationships among users, resources and actions among different web applications such as clouding computing. However, Semantic web applications pose new requirements for security…

Cryptography and Security · Computer Science 2017-11-30 Lili Sun , Jianming Yong , Jeffrey Soar

In biomedical applications of machine learning, relevant information often has a rich structure that is not easily encoded as real-valued predictors. Examples of such data include DNA or RNA sequences, gene sets or pathways, gene…

Genomics · Quantitative Biology 2019-10-16 Jake Crawford , Casey S. Greene

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Coordinated collaboration is essential to realize the added value of and infrastructure requirements for global image data sharing in the life sciences. In this White Paper, we take a first step at presenting some of the most common use…

Inclusion of high throughput technologies in the field of biology has generated massive amounts of biological data in the recent years. Now, transforming these huge volumes of data into knowledge is the primary challenge in computational…

Machine Learning · Computer Science 2021-12-06 Dibyendu Ghosh , Srija Chakraborty , Hariprasad Kodamana , Supriya Chakraborty

Modern biomedical applications often involve time-series data, from high-throughput phenotyping of model organisms, through to individual disease diagnosis and treatment using biomedical data streams. Data and tools for time-series analysis…

Databases · Computer Science 2019-05-06 Ben D. Fulcher , Carl H. Lubba , Sarab S. Sethi , Nick S. Jones

With the rapid advancements in cancer research, the information that is useful for characterizing disease, staging tumors, and creating treatment and survivorship plans has been changing at a pace that creates challenges when physicians try…

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

Biological science produces large amounts of data in a variety of formats, which necessitates the use of computational tools to process, integrate, analyse, and glean insights from the data. Researchers who use computational biology tools…

Human-Computer Interaction · Computer Science 2024-05-10 Yo Yehudi , Lukas Hughes-Noehrer , Carole Goble , Caroline Jay

A vast array of transformative technologies developed over the past decade has enabled measurement and perturbation at ever increasing scale, yet our understanding of many systems remains limited by experimental capacity. Overcoming this…

Quantitative Methods · Quantitative Biology 2020-12-25 Brian Cleary , Aviv Regev

Representing knowledge with the use of ontology description languages offers several advantages arising from knowledge reusability, possibilities of carrying out reasoning processes and the use of existing concepts of knowledge integration.…

Multiagent Systems · Computer Science 2013-04-09 Anna Zygmunt , Jarosław Koźlak , Leszek Siwik

With the adoption of Semantic Web technologies, an increasing number of vocabularies and ontologies have been developed in different domains, ranging from Biology to Agronomy or Geosciences. However, many of these ontologies are still…

Digital Libraries · Computer Science 2020-03-31 Daniel Garijo , María Poveda-Villalón

Biologically inspired computing is an area of computer science which uses the advantageous properties of biological systems. It is the amalgamation of computational intelligence and collective intelligence. Biologically inspired mechanisms…

Neural and Evolutionary Computing · Computer Science 2009-10-22 Sabu M. Thampi

The web information resources are growing explosively in number and volume. Now to retrieve relevant data from web has become very difficult and time-consuming. Semantic Web envisions that these web resources should be developed in…

Software Engineering · Computer Science 2010-06-24 Amjad Farooq , Syed Ahsan , Abad Shah

While the biomedical community has published several "open data" sources in the last decade, most researchers still endure severe logistical and technical challenges to discover, query, and integrate heterogeneous data and knowledge from…

Artificial Intelligence · Computer Science 2020-06-09 Maulik R. Kamdar , Mark A. Musen

Concurrent advances across fields such as organoid technology, Microelectrode Arrays (MEAs), neuromorphic computing, and machine learning have given rise to a groundbreaking research paradigm: Synthetic Biological Intelligence (SBI). SBI…

Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a…

Populations and Evolution · Quantitative Biology 2012-07-25 Christoph Adami

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

Information Integration is a young and exciting field with enormous research and commercial significance in the new world of the Information Society. It stands at the crossroad of Databases and Artificial Intelligence requiring novel…

Artificial Intelligence · Computer Science 2007-05-23 Yannis Dimopoulos , Antonis Kakas
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