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Related papers: A new distance between DNA sequences

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Network data arises through observation of relational information between a collection of entities. Recent work in the literature has independently considered when (i) one observes a sample of networks, connectome data in neuroscience being…

Methodology · Statistics 2022-06-22 George Bolt , Simón Lunagómez , Christopher Nemeth

Which neural networks are similar is a fundamental question for both machine learning and neuroscience. Here, it is proposed to base comparisons on the predictive distributions of linear readouts from intermediate representations. In…

Machine Learning · Computer Science 2025-05-27 Heiko H. Schütt

Generative moment matching network (GMMN) is a deep generative model that differs from Generative Adversarial Network (GAN) by replacing the discriminator in GAN with a two-sample test based on kernel maximum mean discrepancy (MMD).…

Machine Learning · Computer Science 2017-11-28 Chun-Liang Li , Wei-Cheng Chang , Yu Cheng , Yiming Yang , Barnabás Póczos

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

Associating genetic markers with a multidimensional phenotype is an important yet challenging problem. In this work, we establish the equivalence between two popular methods: kernel-machine regression (KMR), and kernel distance covariance…

Machine Learning · Statistics 2014-04-03 Wen-Yu Hua , Debashis Ghosh

Heritability is a central parameter in quantitative genetics, both from an evolutionary and a breeding perspective. For plant traits heritability is traditionally estimated by comparing within and between genotype variability. This approach…

In recent years, deep metric learning has achieved promising results in learning high dimensional semantic feature embeddings where the spatial relationships of the feature vectors match the visual similarities of the images. Similarity…

Machine Learning · Computer Science 2019-09-25 Konstantin Schall , Kai Uwe Barthel , Nico Hezel , Klaus Jung

The task of understanding and interpreting the complex information encoded within genomic sequences remains a grand challenge in biological research and clinical applications. In this context, recent advancements in large language model…

Genomics · Quantitative Biology 2024-09-25 Qihang Zhao , Chi Zhang , Weixiong Zhang

Trajectory inference is a critical problem in single-cell transcriptomics, which aims to reconstruct the dynamic process underlying a population of cells from sequencing data. Of particular interest is the reconstruction of differentiation…

Genomics · Quantitative Biology 2026-04-06 Elodie Maignant , Tim Conrad , Christoph von Tycowicz

We propose a family of near-metrics based on local graph diffusion to capture similarity for a wide class of data sets. These quasi-metametrics, as their names suggest, dispense with one or two standard axioms of metric spaces, specifically…

Machine Learning · Statistics 2017-10-18 Chu Wang , Iraj Saniee , William S. Kennedy , Chris A. White

Generative adversarial networks (GANs) have achieved significant success in generating real-valued data. However, the discrete nature of text hinders the application of GAN to text-generation tasks. Instead of using the standard GAN…

Computation and Language · Computer Science 2020-08-13 Liqun Chen , Shuyang Dai , Chenyang Tao , Dinghan Shen , Zhe Gan , Haichao Zhang , Yizhe Zhang , Lawrence Carin

The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies and biological features inherent in DNA. In this work, we…

Computational Engineering, Finance, and Science · Computer Science 2026-03-09 Qirong Yang , Yucheng Guo , Zicheng Liu , Yujie Yang , Qijin Yin , Siyuan Li , Shaomin Ji , Linlin Chao , Xiaoming Zhang , Stan Z. Li

Deep generative models are universal tools for learning data distributions on high dimensional data spaces via a mapping to lower dimensional latent spaces. We provide a study of latent space geometries and extend and build upon previous…

Machine Learning · Computer Science 2019-02-07 Max F. Frenzel , Bogdan Teleaga , Asahi Ushio

For each rank metric code $\mathcal{C}\subseteq \mathbb{K}^{m\times n}$, we associate a translation structure, the kernel of which is shown to be invariant with respect to the equivalence on rank metric codes. When $\mathcal{C}$ is…

Combinatorics · Mathematics 2017-04-20 Guglielmo Lunardon , Rocco Trombetti , Yue Zhou

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

Populations and Evolution · Quantitative Biology 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

Computing the similarity between two data points plays a vital role in many machine learning algorithms. Metric learning has the aim of learning a good metric automatically from data. Most existing studies on metric learning for…

Machine Learning · Computer Science 2020-03-10 Hikaru Shindo , Masaaki Nishino , Yasuaki Kobayashi , Akihiro Yamamoto

Phylogenetic networks are a generalization of phylogenetic trees that allow for the representation of non-treelike evolutionary events, like recombination, hybridization, or lateral gene transfer. In a recent series of papers devoted to the…

Populations and Evolution · Quantitative Biology 2007-07-17 Gabriel Cardona , Francesc Rossello , Gabriel Valiente

Devising indicative evaluation metrics for the image generation task remains an open problem. The most widely used metric for measuring the similarity between real and generated images has been the Fr\'echet Inception Distance (FID) score.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Muhammad Ferjad Naeem , Seong Joon Oh , Youngjung Uh , Yunjey Choi , Jaejun Yoo

Topological and metric entropies of the DNA sequences from different organisms were calculated. Obtained results were compared each other and with ones of corresponding artificial sequences. For all envisaged DNA sequences there is a…

Statistical Mechanics · Physics 2016-08-31 Olga V. Kirillova

Genome rearrangements are events where large blocks of DNA exchange places during evolution. The analysis of these events is a promising tool for understanding evolutionary genomics, providing data for phylogenetic reconstruction based on…

Computational Complexity · Computer Science 2023-11-30 Luís Cunha , Ignasi Sau , Uéverton Souza