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We present a constructive SAT-based algorithm to determine the multiplicative complexity of a Boolean function, i.e., the smallest number of AND gates in any logic network that consists of 2-input AND gates, 2-input XOR gates, and…

Data Structures and Algorithms · Computer Science 2020-05-06 Mathias Soeken

Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the formalism of Boolean dynamical networks, analyzing the…

Molecular Networks · Quantitative Biology 2021-09-13 Enrico Borriello , Bryan C. Daniels

A Boolean network is a finite dynamical system, whose variables take values from a binary set. The value update rule for each variable is a Boolean function, depending on a selected subset of variables. Boolean networks have been widely…

Dynamical Systems · Mathematics 2017-08-10 Zuguang Gao , Xudong Chen , Tamer Başar

Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology as well as for the dissection of complex pathologic…

Molecular Networks · Quantitative Biology 2007-05-23 Kai Wang , Nilanjana Banerjee , Adam Margolin , Ilya Nemenman , Katia Basso , Riccardo Favera , Andrea Califano

We consider transformations between attractor basins of binary cylindrical cellular automata resulting from mutations. A t-point mutation of a state consists in toggling t sites in that state. Results of such mutations are described by a…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Burton Voorhees , Catherine Beauchemin

Observing the internal state of the whole system using a small number of sensor nodes is important in analysis of complex networks. Here, we study the problem of determining the minimum number of sensor nodes to discriminate attractors…

Data Structures and Algorithms · Computer Science 2021-06-14 Xiaoqing Cheng , Wai-Ki Ching , Sini Guo , Tatsuya Akutsu

Boolean automata networks (aka Boolean networks) are space-time discrete dynamical systems, studied as a model of computation and as a representative model of natural phenomena. A collection of simple entities (the automata) update their…

Discrete Mathematics · Computer Science 2024-02-12 Kévin Perrot , Sylvain Sené , Léah Tapin

Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

Boolean satisfiability (SAT) problems are routinely solved by SAT solvers in real-life applications, yet solving time can vary drastically between solvers for the same instance. This has motivated research into machine learning models that…

We consider networks of delay-coupled Stuart-Landau oscillators. In these systems, the coupling phase has been found to be a crucial control parameter. By proper choice of this parameter one can switch between different synchronous…

Adaptation and Self-Organizing Systems · Physics 2016-08-10 Anton Selivanov , Judith Lehnert , Thomas Dahms , Philipp Hövel , Alexander L. Fradkov , Eckehard Schöll

We show that there is a randomized algorithm that, when given a small constant-depth Boolean circuit $C$ made up of gates that compute constant-degree Polynomial Threshold functions or PTFs (i.e., Boolean functions that compute signs of…

Computational Complexity · Computer Science 2018-09-18 Swapnam Bajpai , Vaibhav Krishan , Deepanshu Kush , Nutan Limaye , Srikanth Srinivasan

The evaluation of the number of attractors in Kauffman networks by Samuelsson and Troein is generalized to critical networks with one input per node and to networks with two inputs per node and different probability distributions for update…

Statistical Mechanics · Physics 2009-11-11 Barbara Drossel

In this paper we study the problem of dynamically maintaining graph properties under batches of edge insertions and deletions in the massively parallel model of computation. In this setting, the graph is stored on a number of machines, each…

Data Structures and Algorithms · Computer Science 2019-08-07 David Durfee , Laxman Dhulipala , Janardhan Kulkarni , Richard Peng , Saurabh Sawlani , Xiaorui Sun

This paper considers the synthesis of distributed reactive control protocols for a Boolean network in a distributed manner. We start with a directed acyclic graph representing a network of Boolean subsystems and a global contract, given as…

Systems and Control · Computer Science 2016-07-15 Yunus Emre Sahin , Necmiye Ozay

We extend a recently introduced class of exactly solvable models for recurrent neural networks with competition between 1D nearest neighbour and infinite range information processing. We increase the potential for further frustration and…

Disordered Systems and Neural Networks · Physics 2009-10-31 N. S. Skantzos , A. C. C. Coolen

The Boolean autonomous dynamical systems, also called regular autonomous asynchronous systems are systems whose 'vector field' is a function {\Phi}:{0,1}^{n}{\to}{0,1}^{n} and time is discrete or continuous. While the synchronous systems…

Other Computer Science · Computer Science 2013-07-23 Serban E. Vlad

This paper is concerned with the reduction of a noisy synchronous Boolean network to a coarse-grained Markov chain with number of states being equal to the number of attractors of the original network.

Biological Physics · Physics 2009-12-21 F. Fourré , D. Baurain

Stability is an important characteristic of network models that has implications for other desirable aspects such as controllability. The stability of a Boolean network depends on various factors, such as the topology of its wiring diagram…

Chaotic Dynamics · Physics 2024-07-09 Karthik Chandrasekhar , Claus Kadelka , Reinhard Laubenbacher , David Murrugarra

The mutations of a complex systemic disease like cancer can be modeled as stuck-at faults in the Boolean system paradigm. For a class of multiple faults, the fault identification is exceptionally significant under the incomplete access of…

Systems and Control · Computer Science 2018-09-11 Anuj Deshpande , Ritwik Kumar Layek

We propose the use of Deterministic Generalized Asynchronous Random Boolean Networks [Gershenson, 2002] as models of contextual deterministic discrete dynamical systems. We show that changes in the context have drastic effects on the global…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Carlos Gershenson , Jan Broekaert , Diederik Aerts