Related papers: A SAT-Based Algorithm for Computing Attractors in …
The Boolean Satisfiability problem (SAT), as the prototypical $\mathsf{NP}$-complete problem, is crucial in both theoretical computer science and practical applications. To address this problem, stochastic local search (SLS) algorithms,…
We present a dynamical system that naturally exhibits two unstable attractors that are completely enclosed by each others basin volume. This counter-intuitive phenomenon occurs in networks of pulse-coupled oscillators with delayed…
This paper studies a control method for switching stable coexisting attractors of a class of non-autonomous dynamical systems. The central idea is to introduce a continuous path for the system's trajectory to transition from its original…
This paper presents a simple periodic parameter-switching method which can find any stable limit cycle that can be numerically approximated in a generalized Duffing system. In this method, the initial value problem of the system is…
Complex diseases can be modeled as damage to intracellular networks that results in abnormal cell behaviors. Network-based dynamic models such as Boolean models have been employed to model a variety of biological systems including those…
Control problem in a biological system is the problem of finding an interventional policy for changing the state of the biological system from an undesirable state, e.g. disease, into a desirable healthy state. Boolean networks are utilized…
This letter describes a method for estimating regions of attraction and bounds on permissible perturbation amplitudes in nonlinear fluids systems. The proposed approach exploits quadratic constraints between the inputs and outputs of the…
In this paper we explore the features of a graph generated by random walkers with nodes that have evolutionary attractiveness and Boltzmann-like transition probabilities that depend both on the euclidean distance between the nodes and on…
Transporting causal information across populations is a critical challenge in clinical decision-making. Causal modeling provides criteria for identifiability and transportability, but these require knowledge of the causal graph, which…
Finite dynamical systems (e.g. Boolean networks and logical models) have been used in modeling biological systems to focus attention on the qualitative features of the system, such as the wiring diagram. Since the analysis of such systems…
In the context of discrete dynamical systems and their applications, fixed points often have a clear interpretation. This is indeed a central topic of gene regulatory mechanisms modeled by Boolean automata networks (BANs), where a…
This paper proposes a new method to reverse engineer gene regulatory networks from experimental data. The modeling framework used is time-discrete deterministic dynamical systems, with a finite set of states for each of the variables. The…
We study the problem of computing a minimal subset of nodes of a given asynchronous Boolean network that need to be controlled to drive its dynamics from an initial steady state (or attractor) to a target steady state. Due to the phenomenon…
Boolean Satisfiability problems are vital components in Electronic Design Automation, particularly within the Logic Equivalence Checking process. Currently, SAT solvers are employed for these problems and neural network is tried as…
Throughout the literature on Neural Cellular Automata (NCAs), it is often taken for granted that the systems learn attractors. This is shown through evolving the system for many timesteps and noting visual similarity to the goal state.…
Fixed points are fundamental states in any dynamical system. In the case of gene regulatory networks (GRNs) they correspond to stable genes profiles associated to the various cell types. We use Kauffman's approach to model GRNs with random…
In this paper we explore challenges in developing a topological framework in which machine learning can be used to robustly characterize global dynamics. Specifically, we focus on learning a useful discretization of the phase space of a…
A conjunctive Boolean network (CBN) is a finite state dynamical system, whose variables take values from a binary set, and the value update rule for each variable is a Boolean function consisting only of logic AND operations. We investigate…
Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…
The growth in number and nature of dynamical attractors in Kauffman NK network models are still not well understood properties of these important random boolean networks. Structural circuits in the underpinning graph give insights into the…