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The extracellular space has an ambiguous role in neuroscience. It is present in every physiologically relevant system and often used as a measurement site in experimental recordings, but it has received subordinate attention compared to the…

Neurons and Cognition · Quantitative Biology 2017-05-02 Jurgis Pods

In studies of the brain and the nervous system, extracellular signals - as measured by local field potentials (LFPs) or electroencephalography (EEG) - are of capital importance, as they allow to simultaneously obtain data from multiple…

Neurons and Cognition · Quantitative Biology 2019-06-10 Jurgis Pods

The Poisson-Nernst-Planck (PNP) system is a standard model for describing ion transport. In many applications, e.g., ions in biological tissues, the presence of thin boundary layers poses both modelling and computational challenges. In a…

Biological Physics · Physics 2018-06-22 Zilong Song , Xiulei Cao , Huaxiong Huang

The Poisson-Nernst-Planck (PNP) system is a standard model for describing ion transport. In many applications, e.g., ions in biological tissues, the presence of thin boundary layers poses both modelling and computational challenges. In this…

Biological Physics · Physics 2018-09-12 Zilong Song , Xiulei Cao , Huaxiong Huang

A model of a finite cylindrical ion channel through a phospholipid membrane of width $L$ separating two electrolyte reservoirs is studied. Analytical solution of the Poisson equation is obtained for an arbitrary distribution of ions inside…

Soft Condensed Matter · Physics 2009-11-11 Yan Levin

Electrical double layer (EDL) is formed when an electrode is in contact with an electrolyte solution, and is widely used in biophysics, electrochemistry, polymer solution and energy storage. Poisson-Boltzmann (PB) coupled equations provides…

Mesoscale and Nanoscale Physics · Physics 2022-03-02 Cherq Chua , Chun Yun Kee , L. K. Ang , Yee Sin Ang

The generation of action potential brings into play specific mechanosensory stimuli manifest in the variation of membrane capacitance, resulting from the selective membrane permeability to ions exchanges and testifying to the central role…

Neurons and Cognition · Quantitative Biology 2021-02-23 Alain M. Dikande

Electrical neural signalling typically takes place at the time-scale of milliseconds, and is typically modeled using the cable equation. This is a good approximation for processes when ionic concentrations vary little during the time course…

Cell Behavior · Quantitative Biology 2014-03-05 Geir Halnes , Ivar Østby , Klas H. Pettersen , Stig W. Omholt , Gaute T. Einevoll

The cell-model and its treatment on the Poisson-Boltzmann level are two important concepts in the theoretical description of charged macromolecules. In this brief contribution to the Proceedings of the NATO-ASI on ``Electrostatic Effects in…

Soft Condensed Matter · Physics 2007-05-23 Markus Deserno , Christian Holm

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

We report here new electrical laws, derived from nonlinear electro-diffusion theory, about the effect of the local geometrical structure, such as curvature, on the electrical properties of a cell. We adopt the Poisson-Nernst-Planck (PNP)…

Subcellular Processes · Quantitative Biology 2017-11-22 Jerome Cartailler , Zeev Schuss , David Holcman

Electrochemical phenomena in biology often unfold in confined geometries where micrometer- to millimeter-scale domains coexist with nanometer-scale interfacial diffuse charge layers. We analyze a model lipid membrane-electrolyte system…

Soft Condensed Matter · Physics 2025-08-20 Joshua B. Fernandes , Hyeongjoo Row , Kranthi K. Mandadapu , Karthik Shekhar

This paper analyzes various schemes for the Euler-Poisson-Boltzmann (EPB) model of plasma physics. This model consists of the pressureless gas dynamics equations coupled with the Poisson equation and where the Boltzmann relation relates the…

Analysis of PDEs · Mathematics 2014-04-08 Pierre Degond , Hailiang Liu , Dominique Savelief , Marie-Hélène Vignal

We consider equilibrium statistical mechanics of a simplified model for the ideal conductor electrode in an interface contact with a classical semi-infinite electrolyte, modeled by the two-dimensional Coulomb gas of pointlike $\pm$ unit…

Statistical Mechanics · Physics 2009-11-11 L. Samaj , Z. Bajnok

The electron and current density distributions in the close proximity of quantum point contacts (QPCs) are investigated. A three dimensional Poisson equation is solved self-consistently to obtain the electron density and potential profile…

Mesoscale and Nanoscale Physics · Physics 2009-11-13 S. Arslan , E. Cicek , D. Eksi , S. Aktas , A. Weichselbaum , A. Siddiki

We consider an osmotic equilibrium between bulk solutions of polyelectrolyte bounded by semipermeable membranes and separated by a thin film of salt-free liquid. Although the membranes are neutral, the counter-ions of the polyelectrolyte…

Soft Condensed Matter · Physics 2012-01-19 Olga I. Vinogradova , Lyderic Bocquet , Artem N. Bogdanov , Roumen Tsekov , Vladimir Lobaskin

In this chapter we review the electrostatic properties of charged membranes in aqueous solutions, with or without added salt, employing simple physical models. The equilibrium ionic profiles close to the membrane are governed by the…

Soft Condensed Matter · Physics 2023-01-05 Tomer Markovich , David Andelman , Rudi Podgornik

The description of a conducting medium in thermal equilibrium, such as an electrolyte solution or a plasma, involves nonlinear electrostatics, a subject rarely discussed in the standard electricity and magnetism textbooks. We consider in…

Chemical Physics · Physics 2018-08-01 C. G. Gray , P. J. Stiles

We show that charge-sign-dependent asymmetric hydration can be modeled accurately using linear Poisson theory but replacing the standard electric-displacement boundary condition with a simple nonlinear boundary condition. Using a single…

Chemical Physics · Physics 2015-06-23 Jaydeep P. Bardhan , Matthew G. Knepley

We study the geometric particle-in-cell methods for an electrostatic hybrid plasma model. In this model, ions are described by the fully kinetic equations, electron density is determined by the Boltzmann relation, and space-charge effects…

Numerical Analysis · Mathematics 2026-03-26 Yingzhe Li
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