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The activity of a neural network is defined by patterns of spiking and silence from the individual neurons. Because spikes are (relatively) sparse, patterns of activity with increasing numbers of spikes are less probable, but with more…

Neurons and Cognition · Quantitative Biology 2025-02-13 Gasper Tkacik , Thierry Mora , Olivier Marre , Dario Amodei , Michael J. Berry , William Bialek

Networks of randomly connected neurons are among the most popular models in theoretical neuroscience. The connectivity between neurons in the cortex is however not fully random, the simplest and most prominent deviation from randomness…

Neurons and Cognition · Quantitative Biology 2018-07-09 Daniel Martí , Nicolas Brunel , Srdjan Ostojic

Neocortical neurons have thousands of excitatory synapses. It is a mystery how neurons integrate the input from so many synapses and what kind of large-scale network behavior this enables. It has been previously proposed that non-linear…

Neurons and Cognition · Quantitative Biology 2016-04-25 Jeff Hawkins , Subutai Ahmad

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

Neurons and Cognition · Quantitative Biology 2016-05-04 Ryan Pyle , Robert Rosenbaum

Temporal social networks of human interactions are preponderant in understanding the fundamental patterns of human behavior. In these networks, interactions occur locally between individuals (i.e., nodes) who connect with each other at…

Physics and Society · Physics 2022-10-11 Shaunette T. Ferguson , Teruyoshi Kobayashi

Correlated electrical activity in neurons is a prominent characteristic of cortical microcircuits. Despite a growing amount of evidence concerning both spike-count and subthreshold membrane potential pairwise correlations, little is known…

Neurons and Cognition · Quantitative Biology 2019-07-29 Daniele Linaro , Gabriel K. Ocker , Brent Doiron , Michele Giugliano

We analyze the collective dynamics of hierarchically structured networks of densely connected spiking neurons. These networks of sub-networks may represent interactions between cell assemblies or different nuclei in the brain. The dynamical…

Neurons and Cognition · Quantitative Biology 2018-09-14 Fereshteh Lagzi , Fatihcan M. Atay , Stefan Rotter

A computer model is described which is used to assess the dynamical complexity of a class of networks of spiking neurons with small-world properties. Networks are constructed by forming an initially segregated set of highly intra-connected…

Biological Physics · Physics 2009-11-13 Murray Shanahan

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 Vesna Vuksanović , Philipp Hövel

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

Neurons and Cognition · Quantitative Biology 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

The network density matrix formalism allows for describing the dynamics of information on top of complex structures and it has been successfully used to analyze from system's robustness to perturbations to coarse graining multilayer…

Physics and Society · Physics 2023-05-03 Arsham Ghavasieh , Manlio De Domenico

The expressive power of artificial neural networks crucially depends on the nonlinearity of their activation functions. Though a wide variety of nonlinear activation functions have been proposed for use in artificial neural networks, a…

Disordered Systems and Neural Networks · Physics 2021-02-24 Jacob A. Zavatone-Veth , Cengiz Pehlevan

Understanding the nature of the changes exhibited by evolving neuronal dynamics from high-dimensional activity data is essential for advancing neuroscience, particularly in the study of neuronal network development and the pathophysiology…

Neurons and Cognition · Quantitative Biology 2025-03-03 Ho Fai Po , Akke Mats Houben , Anna-Christina Haeb , Yordan P. Raykov , Daniel Tornero , Jordi Soriano , David Saad

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

Previous studies have demonstrated the importance of the primary sensory cortex for the detection, discrimination and awareness of visual stimuli, but it is unknown how neuronal populations in this area process detected and undetected…

Neurons and Cognition · Quantitative Biology 2015-12-03 Jorrit S. Montijn , Pieter M. Goltstein , Cyriel M. A. Pennartz

We consider a sparse random network of excitatory leaky integrate-and-fire neurons with short-term synaptic depression. Furthermore to mimic the dynamics of a brain circuit in its first stages of development we introduce for each neuron…

Neurons and Cognition · Quantitative Biology 2017-03-14 S. Luccioli , A. Barzilai , E. Ben-Jacob , P. Bonifazi , A. Torcini

In this paper we address the question of statistical model selection for a class of stochastic models of biological neural nets. Models in this class are systems of interacting chains with memory of variable length. Each chain describes the…

Statistics Theory · Mathematics 2018-12-19 A. Duarte , A. Galves , E. Löcherbach , G. Ost

Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…

Neurons and Cognition · Quantitative Biology 2015-06-03 Demian Battaglia , Annette Witt , Fred Wolf , Theo Geisel

Gap-junctional coupling is an important way of communication between neurons and other excitable cells. Strong electrical coupling synchronizes activity across cell ensembles. Surprisingly, in the presence of noise synchronous oscillations…

Adaptation and Self-Organizing Systems · Physics 2012-06-05 Georgi S. Medvedev , Svitlana Zhuravytska

Many experiments have evidenced that electrical and chemical synapses -- hybrid synapses -- coexist in most organisms and brain structures. The role of electrical and chemical synapse connection in diversity of neural activity generation…

Neurons and Cognition · Quantitative Biology 2021-08-11 Kesheng Xu , Jean Paul Maidana , Patricio Orio