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I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules. In light of a fundamental symmetry principle, the typical…

Subcellular Processes · Quantitative Biology 2015-06-03 Christopher L. Henley

Most animal body plans have some degree of left-right asymmetry. This chirality at the tissue and organ level is often assumed to originate from the intrinsic handedness of biological molecules. How this handedness might be transferred from…

Tissues and Organs · Quantitative Biology 2017-08-30 Jeremy Hadidjojo , David K. Lubensky

A computational theory and model of the ontogeny and development of bilateral symmetry in multicellular organisms is presented. Understanding the origin and evolution of bilateral organisms requires an understanding of how bilateral…

Tissues and Organs · Quantitative Biology 2012-07-16 Eric Werner

We study quantum systems with broken symmetry that can be modelled as cyclic three-level atoms with coexisting one- and two-photon transitions. They can be selectively optically excited to any state. As an example, we show that left- and…

Quantum Physics · Physics 2008-01-28 Yong Li , C. Bruder

In multicellular organisms, relations among parts and between parts and the whole are contextual and interdependent. These organisms and their cells are ontogenetically linked: an organism starts as a cell that divides producing…

Other Quantitative Biology · Quantitative Biology 2017-09-15 Maël Montévil , Lucia Speroni , Carlos Sonnenschein , Ana M. Soto

Internal microscopic symmetry of a many body system leads to global constraints. We obtain explicit forms of the global macroscopic condition assuring that at the microscopic level the evolution respects the overall symmetry.

High Energy Physics - Theory · Physics 2007-05-23 Ludwik Turko

The vast majority of multi-cellular organisms are anisogamous, meaning that male and female sex cells differ in size. It remains an open question how this asymmetric state evolved, presumably from the symmetric isogamous state where all…

Populations and Evolution · Quantitative Biology 2021-12-20 Joseph D. Johnson , Nathan L. White , Alain Kangabire , Daniel M. Abrams

Multicellular self-organization drives development in biological organisms, yet a comprehensive theory is lacking as basic properties of cells can complicate common approaches. Framing such properties by dynamic graphs led to new…

Molecular Networks · Quantitative Biology 2026-05-26 Kyle R. Allison

Symmetry invariant local interaction of a many body system leads to global constraints. We obtain explicit forms of the global macroscopic condition assuring that at the microscopic level the evolution respects the overall symmetry.

High Energy Physics - Theory · Physics 2009-11-07 Ludwik Turko

For standard leptogenesis from the decay of singlet right-handed neutrinos, we derive source terms for the lepton asymmetry that are present in a finite density background but absent in the vacuum. These arise from cuts through the vertex…

High Energy Physics - Phenomenology · Physics 2011-06-02 Bjorn Garbrecht

Understanding biological phenomena requires a systemic approach that incorporates different mechanisms acting on different spatial and temporal scales, since in organisms the workings of all components, such as organelles, cells, and organs…

Tissues and Organs · Quantitative Biology 2015-09-14 Yuri K. Shestopaloff , Ivo F. Sbalzarini

Through extensive studies of dynamical system modeling cellular growth and reproduction, we find evidence that complexity arises in multicellular organisms naturally through evolution. Without any elaborate control mechanism, these systems…

Adaptation and Self-Organizing Systems · Physics 2009-10-31 Chikara Furusawa , Kunihiko Kaneko

The article seeks to formulate a synergetic law that is posited to be of common physicochemical and biological nature: an evolving system, possessing free energy and elements with chiral asymmetry may change the type of symmetry inside one…

Adaptation and Self-Organizing Systems · Physics 2012-12-10 Vsevolod A. Tverdislov

Handedness in humans - better performance using either the left or right hand - is personally familiar, moderately heritable, and regulated by many genes, including those involved in general body symmetry. But behavioral handedness, i.e.…

Neurons and Cognition · Quantitative Biology 2016-07-13 Sean Buchanan , Jamey Kain , Benjamin de Bivort

Cells contain elaborate and interconnected networks of protein polymers which make up the cytoskeleton. The cytoskeleton governs the internal positioning and movement of vesicles and organelles, and controls dynamic changes in cell…

Biological Physics · Physics 2017-01-24 Lishibanya Mohapatra , Bruce L. Goode , Predrag Jelenkovic , Rob Phillips , Jane Kondev

Many organs of higher organisms are heavily branched structures and arise by an at first sight similar process of branching morphogenesis. Yet the regulatory components and local interactions that have been identified differ greatly in…

Tissues and Organs · Quantitative Biology 2013-08-12 Dagmar Iber , Denis Menshykau

The orientation of the angular momentum vector with respect to the triaxial density distribution selects a left-handed or right-handed system principal axes. This breaking of chiral symmetry manifests itself as pairs of nearly identical…

Nuclear Theory · Physics 2009-11-07 V. Dimitrov , F. Dönau , S. Frauendorf

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…

Soft Condensed Matter · Physics 2025-09-04 James Clarke , Jake McGrath , Colin Johnson , José Alvarado

Animals and robots must self-right on the ground after overturning. Biology research described various strategies and motor patterns in many species. Robotics research devised many strategies. However, we do not well understand how the…

Biological Physics · Physics 2024-10-01 Chen Li
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