Related papers: Possible mechanisms for initiating macroscopic lef…
Scaling laws illuminate Nature's fundamental biological principles and guide bioinspired materials and structural designs. In simple cases they are based on the fundamental principle that all laws of nature remain unchanged (i.e.,…
The observed general time-asymmetric behavior of macroscopic systems -- embodied in the second law of thermodynamics -- arises naturally from time-symmetric microscopic laws due to the great disparity between macro and micro-scales. More…
Branching in vascular networks and in overall organismic form is one of the most common and ancient features of multicellular plants, fungi, and animals. By combining machine-learning techniques with new theory that relates vascular form to…
Organogenesis involves large deformations and complex shape changes that require elaborate mechanical regulation. Models of tissue biomechanics have been introduced to account for the coupling between mechanical response and biochemical…
The difference between left- and right-handed particles is perhaps one of the most puzzling aspects of the Standard Model (SM). In left-right models (LRMs) the symmetry between left- and right-handed particles can be restored at high…
Instead of creating the observed baryon asymmetry of the universe by the decay of right-handed (RH) neutrinos to left-handed leptons, we propose to generate it dominantly by the decay of the RH neutrinos to RH leptons. This mechanism turns…
The origin of allometric scaling of metabolic rate is a long-standing question in biology. Several models have been proposed for explaining the origin; however, they have advantages and disadvantages. In particular, previous models only…
The present view of biological phenomena is based on a biochemical paradigm that development of living organisms is defined by information stored in a molecular form as some genetic code. However, new discoveries indicate that biological…
The emergence of large scale structures in biological systems, and in particular the formation of lines of hierarchy, is observed in many scales, from collections of cells to groups of insects to herds of animals. Motivated by phenomena in…
We propose a new mechanism for baryogenesis. We study the effective potential of left-right extension of the standard model and show that there can be a first order phase transition at the left-right symmetry breaking and hence $(B-L)$…
Several aspects of mathematical astrobiology are discussed. It is argued that around the time of the origin of life the handedness of biomolecules must have established itself through an instability. Possible pathways of producing a certain…
The dynamics governing the evolution of a many body system is constrained by a nonabelian local symmetry. We obtain explicit forms of the global macroscopic condition assuring that at the microscopic level the evolution respects the overall…
Reaction-diffusion equations based on a polymerization model are solved to simulate the spreading of hypothetic left and right handed life forms on the Earth's surface. The equations exhibit front-like behavior as is familiar from the…
Recent 3D organ reconstitution studies show that a group of stem cells can establish a body axis and acquire different fates in a spatially organized manner. How such symmetry breaking happens in the absence of external spatial cues, and…
One of the fundamental problems in biology concerns the method by which a cluster of organisms can regulate the proportion of individuals that perform various roles or modes as if each individual knows a whole situation without a leader. A…
Time-asymmetric behavior as embodied in the second law of thermodynamics is observed in {\it individual macroscopic} systems. It can be understood as arising naturally from time-symmetric microscopic laws when account is taken of a) the…
Most biomolecules occur in mirror, or chiral, images of each other. However, life is homochiral: proteins contain almost exclusively levorotatory (L) amino acids, while only dextrorotatory (R) sugars appear in RNA and DNA. The mechanism…
A transition from asymmetric to symmetric patterns in time-dependent extended systems is described. It is found that one dimensional cellular automata, started from fully random initial conditions, can be forced to evolve into complex…
The organization of live cells into tissues and their subsequent biological function involves inter-cell mechanical interactions, which are mediated by their elastic environment. To model this interaction, we consider cells as spherical…
One of the most fundamental rules in metabolic ecology is the allometric equation, which is a power-law scaling that describes the connection between body measurements and body size. The biological dynamics of this essentially empirical…