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Human immunodeficiency virus (HIV) evolves with extraordinary rapidity. However, its evolution is constrained by interactions between mutations in its fitness landscape. Here we show that an Ising model describing these interactions,…

Populations and Evolution · Quantitative Biology 2016-02-24 Thomas C. Butler , John P. Barton , Mehran Kardar , Arup K. Chakraborty

Novel criteria for global asymptotic stability of nonlinear uncertain finite-dimensional systems are presented. The results are obtained by a combination of the "discretization approach" and the ideas contained in the proof of the original…

Optimization and Control · Mathematics 2009-07-24 Iasson Karafyllis

We consider a class of nonlinear differential equations that arises in the study of chemical reaction systems that are known to be locally asymptotically stable and prove that they are in fact globally asymptotically stable. More…

Dynamical Systems · Mathematics 2007-11-16 David F. Anderson

This paper investigates the global stability and the global asymptotic stability independent of the sizes of the delays of linear time-varying Caputo fractional dynamic systems of real fractional order possessing internal point delays. The…

Dynamical Systems · Mathematics 2010-10-18 M. De La Sen

In this work, we propose the design and analysis of a novel continuous robust controller for a class of multi--input multi--output (MIMO) nonlinear uncertain systems. The systems under consideration contains unstructured uncertainties in…

Optimization and Control · Mathematics 2013-01-24 Baris Bidikli , Enver Tatlicioglu , Erkan Zergeroglu , Alper Bayrak

This paper shows the global existence and boundedness of solutions of a reaction diffusion system modeling liver infections. The existence proof is presented step by step and the focus lies on the interpretation of intermediate results in…

Analysis of PDEs · Mathematics 2023-08-02 Cordula Reisch , Dirk Langemann

We study the stability properties of a class of time-varying nonlinear systems. We assume that non-strict input-to-state stable (ISS) Lyapunov functions for our systems are given and posit a mild persistency of excitation condition on our…

Optimization and Control · Mathematics 2007-05-23 Michael Malisoff , Frederic Mazenc

Railway tracks rest on a foundation known for exhibiting nonlinear viscoelastic behavior. Railway track deflections are modeled by a semilinear partial differential equation. This paper studies the stability of solutions to this equation in…

Analysis of PDEs · Mathematics 2018-07-04 M. Sajjad Edalatzadeh , Kirsten A. Morris

In this manuscript we consider an age structured epidemic system modelling the dynamics of transmission of immunizing disease like Hepatitis B virus. Our model takes into account age as well as two classes of infected individuals (chronic…

Analysis of PDEs · Mathematics 2016-05-17 Yannick Tchaptchie Kouakep

When an infectious disease propagates throughout society, the incidence function may rise at first due to an increase in pathogenicity and then decrease due to inhibitory effects until it reaches saturation. Effective vaccination and…

Dynamical Systems · Mathematics 2023-07-11 Sushil Pathak , G. Shirisha , K. Venkata Ratnam

The Vlasov equation is well known to provide a good description of the dynamics of mean-field systems in the $N \to \infty$ limit. This equation has an infinity of stationary states and the case of {\it homogeneous} states, for which the…

Statistical Mechanics · Physics 2015-03-31 Romain Bachelard , F. Staniscia , Thierry Dauxois , G. De Ninno , S. Ruffo

Mathematical models of glucose, insulin, and pancreatic $\beta$-cell mass dynamics are essential for understanding the physiological basis of type 2 diabetes. This paper investigates the Topp model's discrete-time dynamics to represent…

Dynamical Systems · Mathematics 2024-05-02 Z. S. Boxonov , U. A. Rozikov

We provide explicit conditions for uniform stability, global asymptotic stability and uniform exponential stability for dynamic equations with a single delay and a nonnegative coefficient. Some examples on nonstandard time scales are also…

Dynamical Systems · Mathematics 2019-02-21 Elena Braverman , Basak Karpuz

The notion of the relaxed Robust Control Lyapunov Function (relaxed RCLF) is introduced and is exploited for the design of robust feedback stabilizers for nonlinear systems. Particularly, it is shown for systems with input constraints that…

Optimization and Control · Mathematics 2008-10-07 Iasson Karafyllis , Costas Kravaris , Nicolas Kalogerakis

In this report we deal with the problem of global output feedback stabilization of a class of $n$-dimensional nonlinear positive systems possessing a one-dimensional unknown, though measured, part. We first propose our main result, an…

Optimization and Control · Mathematics 2016-08-16 Jean-Luc Gouzé , Olivier Bernard , Ludovic Mailleret

In this his paper, we studied the global dynamics of a two-strain flu model with a single-strain vaccine and general incidence rate. Four equilibrium points were obtained and the global dynamics of the model are completely determined via…

Dynamical Systems · Mathematics 2020-04-23 Arturo J. Nic May , Eric J. Avila Vales

This paper investigates dynamic behaviors of the tumor-immune system perturbed by environmental noise. The model describes the response of the cytotoxic T lymphocyte (CTL) to the growth of an immunogenic tumour. The main methods are…

Probability · Mathematics 2019-02-06 Xiaoyue Li , Guoting Song , Yang Xia , Chenggui Yuan

In this research, we have derived a mathematical model for within human dynamics of COVID-19 infection using delay differential equations. The new model considers a 'latent period' and 'the time for immune response' as delay parameters,…

Populations and Evolution · Quantitative Biology 2025-01-14 Amar N. Chatterjee , Teklebirhan Abraha , Fahad Al Basir , Delfim F. M. Torres

The topic of this manuscript is the stability analysis of continuous-time switched nonlinear systems with constraints on the admissible switching signals. Our particular focus lies in considering signals characterized by upper and lower…

Optimization and Control · Mathematics 2024-01-17 Matteo Della Rossa

In kinetic theory, a system is usually described by its one-particle distribution function $f(\mathbf{r},\mathbf{v},t)$, such that $f(\mathbf{r},\mathbf{v},t)d\mathbf{r} d\mathbf{v}$ is the fraction of particles with positions and…

Statistical Mechanics · Physics 2017-05-17 C. A. Plata , A. Prados