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A central question in neuroscience is to understand how noisy firing patterns are used to transmit information. Because neural spiking is noisy, spiking patterns are often quantified via pairwise correlations, or the probability that two…

Neurons and Cognition · Quantitative Biology 2017-05-29 Andrea K. Barreiro , Cheng Ly

The activity of neurons within brain circuits has been ubiquitously reported to be correlated. The impact of these correlations on brain function has been extensively investigated. Correlations can in principle increase or decrease the…

Neurons and Cognition · Quantitative Biology 2025-07-24 Miguel Ibáñez-Berganza , Giulio Bondanelli , Stefano Panzeri

Neural networks encode information through their collective spiking activity in response to external stimuli. This population response is noisy and strongly correlated, with complex interplay between correlations induced by the stimulus,…

Neurons and Cognition · Quantitative Biology 2022-11-28 Gabriel Mahuas , Olivier Marre , Thierry Mora , Ulisse Ferrari

Which statistical features of spiking activity matter for how stimuli are encoded in neural populations? A vast body of work has explored how firing rates in individual cells and correlations in the spikes of cell pairs impact coding. But…

Neurons and Cognition · Quantitative Biology 2014-12-02 Alex Cayco-Gajic , Joel Zylberberg , Eric Shea-Brown

In a recent study the initial rise of the mutual information between the firing rates of N neurons and a set of p discrete stimuli has been analytically evaluated, under the assumption that neurons fire independently of one another to each…

Disordered Systems and Neural Networks · Physics 2009-11-07 Valeria Del Prete , Alessandro Treves

Stimulus from the environment that guides behavior and informs decisions is encoded in the firing rates of neural populations. Each neuron in the populations, however, does not spike independently: spike events are correlated from cell to…

Neurons and Cognition · Quantitative Biology 2012-07-24 Nicholas Cain , Eric Shea-Brown

When two stimuli are present in the receptive field of a V4 neuron, the firing rate response is between the weakest and strongest response elicited by each of the stimuli alone (Reynolds et al, 1999, Journal of Neuroscience 19:1736-1753).…

Neurons and Cognition · Quantitative Biology 2007-05-23 Paul H. Tiesinga

The correlated variability in the responses of a neural population to the repeated presentation of a sensory stimulus is a universally observed phenomenon. Such correlations have been studied in much detail, both with respect to their…

Neurons and Cognition · Quantitative Biology 2018-07-04 Volker Pernice , Rava Azeredo da Silveira

We study the capacity with which a system of independent neuron-like units represents a given set of stimuli. We assume that each neuron provides a fixed amount of information, and that the information provided by different neurons has a…

Disordered Systems and Neural Networks · Physics 2007-05-23 Ines Samengo

Positive correlations in the activity of neurons are widely observed in the brain. Previous studies have shown these correlations to be detrimental to the fidelity of population codes or at best marginally favorable compared to independent…

Neurons and Cognition · Quantitative Biology 2013-07-22 Rava Azeredo da Silveira , Michael J. Berry

Humans and other animals base their decisions on noisy sensory input. Much work has therefore been devoted to understanding the computations that underly such decisions. The problem has been studied in a variety of tasks and with stimuli of…

Neurons and Cognition · Quantitative Biology 2015-03-05 Manisha Bhardwaj , Sam Carroll , Wei Ji Ma , Kresimir Josic

Redundancies and correlations in the responses of sensory neurons seem to waste neural resources but can carry cues about structured stimuli and may help the brain to correct for response errors. To assess how the retina negotiates this…

Neurons and Cognition · Quantitative Biology 2014-03-05 K. D. Simmons , J. S. Prentice , G. Tkacik , J. Homann , H. K. Yee , S. E. Palmer , P. C. Nelson , V. Balasubramanian

At the single-neuron level, precisely timed spikes can either constitute firing-rate codes or spike-pattern codes that utilize the relative timing between consecutive spikes. There has been little experimental support for the hypothesis…

Neurons and Cognition · Quantitative Biology 2009-12-18 Hugo Gabriel Eyherabide , Ariel Rokem , Andreas V. M. Herz , Ines Samengo

Over repeat presentations of the same stimulus, sensory neurons show variable responses. This "noise" is typically correlated between pairs of cells, and a question with rich history in neuroscience is how these noise correlations impact…

Neurons and Cognition · Quantitative Biology 2015-06-16 Yu Hu , Joel Zylberberg , Eric Shea-Brown

The coding properties of cells with different types of receptive fields have been studied for decades. ON-type neurons fire in response to positive fluctuations of the time-dependent stimulus, whereas OFF cells are driven by negative…

Neurons and Cognition · Quantitative Biology 2009-09-10 Eugenio Urdapilleta , Ines Samengo

Neural correlations play a critical role in sensory information coding. They are of two kinds: signal correlations, when neurons have overlapping sensitivities, and noise correlations from network effects and shared noise. In experiments…

Neurons and Cognition · Quantitative Biology 2025-07-03 Gabriel Mahuas , Thomas Buffet , Olivier Marre , Ulisse Ferrari , Thierry Mora

A general method for deriving maximally informative sigmoidal tuning curves for neural systems with small normalized variability is presented. The optimal tuning curve is a nonlinear function of the cumulative distribution function of the…

Neurons and Cognition · Quantitative Biology 2008-08-02 Mark D. McDonnell , Nigel G. Stocks

Advances in large-scale neural recordings have expanded our ability to describe the activity of distributed brain circuits. However, understanding how neural population dynamics differ across regions and behavioral contexts remains…

Most neurons in the primary visual cortex initially respond vigorously when a preferred stimulus is presented, but adapt as stimulation continues. The functional consequences of adaptation are unclear. Typically a reduction of firing rate…

Neurons and Cognition · Quantitative Biology 2011-03-15 J. M. Cortes , D. Marinazzo , P. Series , M. W. Oram , T. J. Sejnowski , M. C. W. van Rossum

One of the fundamental characteristics of a nonlinear system is how it transfers correlations in its inputs to correlations in its outputs. This is particularly important in the nervous system, where correlations between spiking neurons are…

Neurons and Cognition · Quantitative Biology 2013-05-29 Eric Shea-Brown , Kresimir Josic , Jaime de la Rocha , Brent Doiron
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