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We present a lightweight approach to sequence classification using Ensemble Methods for Hidden Markov Models (HMMs). HMMs offer significant advantages in scenarios with imbalanced or smaller datasets due to their simplicity,…

Machine Learning · Computer Science 2024-09-13 Maxime Kawawa-Beaudan , Srijan Sood , Soham Palande , Ganapathy Mani , Tucker Balch , Manuela Veloso

The development of enhanced sampling methods has greatly extended the scope of atomistic simulations, allowing long-time phenomena to be studied with accessible computational resources. Many such methods rely on the identification of an…

Computational Physics · Physics 2022-06-08 Luigi Bonati , GiovanniMaria Piccini , Michele Parrinello

Numerical resolution of high-dimensional nonlinear PDEs remains a huge challenge due to the curse of dimensionality. Starting from the weak formulation of the Lawson-Euler scheme, this paper proposes a stochastic particle method (SPM) by…

Numerical Analysis · Mathematics 2025-02-11 Zhengyang Lei , Sihong Shao , Yunfeng Xiong

We introduce a method to compute the reweighted path ensemble by combining transition interface sampling simulations conditioned on different collective variables. The approach is based on the Multistate Bennett Acceptance Ratio (MBAR)…

Statistical Mechanics · Physics 2026-04-20 Rik S. Breebaart , Peter G. Bolhuis

Nested case-control (NCC) is a sampling method widely used for developing and evaluating risk models with expensive biomarkers on large prospective cohort studies. The biomarker values are typically obtained on a sub-cohort, consisting of…

Methodology · Statistics 2021-04-07 Qian M. Zhou , Xuan Wang , Yingye Zheng , Tianxi Cai

Recent developments in generative modeling have utilized score-based methods coupled with stochastic differential equations to sample from complex probability distributions. However, these and other performant sampling methods generally…

Machine Learning · Computer Science 2025-06-03 Bryan Riel , Tobias Bischoff

Community structure is common in many real networks, with nodes clustered in groups sharing the same connections patterns. While many community detection methods have been developed for networks with binary edges, few of them are applicable…

Methodology · Statistics 2023-03-13 Andressa Cerqueira , Elizaveta Levina

We propose a data-driven method to learn the time-dependent probability density of a multivariate stochastic process from sample paths, assuming that the initial probability density is known and can be evaluated. Our method uses a novel…

Machine Learning · Statistics 2025-06-19 Agnimitra Dasgupta , Javier Murgoitio-Esandi , Ali Fardisi , Assad A Oberai

Machine learning for the parameterization of subgrid-scale processes in climate models has been widely researched and adopted in a few models. A key challenge in developing data-driven parameterization schemes is how to properly represent…

Atmospheric and Oceanic Physics · Physics 2024-02-29 L. Minah Yang , Edwin P. Gerber

The problem of studying rare events is central to many areas of computer simulations. In a recent paper [Kang, P., et al., Nat. Comput. Sci. 4, 451-460, 2024], we have shown that a powerful way of solving this problem passes through the…

Computational Physics · Physics 2026-03-03 Enrico Trizio , Peilin Kang , Michele Parrinello

The weighted sum method is a simple and widely used technique that scalarizes multiple conflicting objectives into a single objective function. It suffers from the problem of determining the appropriate weights corresponding to the…

Artificial Intelligence · Computer Science 2020-05-07 Romit S Beed , Sunita Sarkar , Arindam Roy , Durba Bhattacharya

The doubly robust estimator, which models both the propensity score and outcomes, is a popular approach to estimate the average treatment effect in the potential outcome setting. The primary appeal of this estimator is its theoretical…

Methodology · Statistics 2024-09-11 Kaoru Babasaki , Shonosuke Sugasawa , Kosaku Takanashi , Kenichiro McAlinn

Image classification technology and performance based on Deep Learning have already achieved high standards. Nevertheless, many efforts have conducted to improve the stability of classification via ensembling. However, the existing ensemble…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 YeongHyeon Park , JoonSung Lee , Wonseok Park

Markov State Models (MSM) are widely used to elucidate dynamic properties of molecular systems from unbiased Molecular Dynamics (MD). However, the implementation of reweighting schemes for MSMs to analyze biased simulations, for example…

Chemical Physics · Physics 2020-11-26 Stefanie Kieninger , Luca Donati , Bettina G. Keller

Sampling from a dynamic discrete distribution means drawing an index with probability proportional to a mutable set of weights. Classical constant-time techniques such as the Alias Method are well suited to static distributions, but become…

Data Structures and Algorithms · Computer Science 2026-04-28 Lilith Orion Hafner , Adriano Meligrana

We propose an efficient novel path sampling-based framework designed to accelerate the investigation of rare events in complex molecular systems. A key innovation is the shift from sampling restricted path ensemble distributions, as in…

Chemical Physics · Physics 2025-03-28 Gianmarco Lazzeri , Peter G. Bolhuis , Roberto Covino

We investigate the utility to computational Bayesian analyses of a particular family of recursive marginal likelihood estimators characterized by the (equivalent) algorithms known as "biased sampling" or "reverse logistic regression" in the…

Methodology · Statistics 2014-10-16 Ewan Cameron , Anthony Pettitt

In this paper, we introduce a new algorithm for rare event estimation based on adaptive importance sampling. We consider a smoothed version of the optimal importance sampling density, which is approximated by an ensemble of interacting…

Computation · Statistics 2023-04-19 Konstantin Althaus , Iason Papaioannou , Elisabeth Ullmann

We employ the Bayesian improved cross entropy (BiCE) method for rare event estimation in static networks and choose the categorical mixture as the parametric family to capture the dependence among network components. At each iteration of…

Methodology · Statistics 2023-09-25 Jianpeng Chan , Iason Papaioannou , Daniel Straub

This paper evaluates six strategies for mitigating imbalanced data: oversampling, undersampling, ensemble methods, specialized algorithms, class weight adjustments, and a no-mitigation approach referred to as the baseline. These strategies…

Machine Learning · Computer Science 2023-11-13 Jacques Wainer