Related papers: Contagious obesity: from adenovirus 36 to RB dysfu…
Many emerging pathogens infect multiple host species, and multi-host pathogens may have very different dynamics in different host species. This research addresses how pathogen replication rates and Immune System (IS) response times are…
The toxins associated with infectious diseases are potential targets for inhibitors which have the potential for prophylactic or therapeutic use. Many antibodies have been generated for this purpose, and the objective of this study was to…
In this paper, we consider recent progress in estimating the average treatment effect when extreme inverse probability weights are present and focus on methods that account for a possible violation of the positivity assumption. These…
One of the major research questions regarding human microbiome studies is the feasibility of designing interventions that modulate the composition of the microbiome to promote health and cure disease. This requires extensive understanding…
Chronic Obstructive Pulmonary Disease (COPD) is an irreversible airway obstruction with a high societal burden. Although smoking is known to be the biggest risk factor, additional components need to be considered. In this study, we aim to…
Overweight and obese individuals tend to have increased brain age, reflecting poorer brain health likely due to grey and white matter atrophy related to obesity. However, it is unclear if older brain age associated with obesity can be…
In the context of the global obesity epidemic, it is important to know who becomes obese and why. However, the processes that determine the changing shape of Body Mass Index (BMI) distributions in high-income societies are not…
Diabetic Retinopathy (DR) is an eye disease which arises due to diabetes mellitus. It might cause vision loss and blindness. To prevent irreversible vision loss, early detection through systematic screening is crucial. Although researchers…
An imbalance between energy intake and energy expenditure will lead to a change in body weight (mass) and body composition (fat and lean masses). A quantitative understanding of the processes involved, which currently remains lacking, will…
Background. Diet and inflammation are critical factors influencing cancer risk. However, the combined impact of nutritional status and inflammatory biomarkers on cancer status and type, using machine learning (ML), remains underexplored.…
Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…
Weighting methods are used in observational studies to adjust for covariate imbalances between treatment and control groups. Entropy balancing (EB) is an alternative to inverse probability weighting with an estimated propensity score. The…
Using our previously developed model we demonstrate here, that (1) solid tumor growth and cell invasion are linked, not only qualitatively but also quantitatively, that (2) the onset of invasion marks the time point when the tumor cell…
Understanding the risk and protective factors associated with Parkinsons disease (PD) is crucial for improving outcomes for patients, individuals at risk, healthcare providers, and healthcare systems. Studying these factors not only…
A prominent threat to causal inference about peer effects over social networks is the presence of homophily bias, that is, social influence between friends and families is entangled with common characteristics or underlying similarities…
We consider the bimolecular charge carrier recombination in amorphous organic semiconductors having a special kind of energetic disorder where energy levels for electrons and holes at a given transport site move in the same direction with…
Obesity affects a rising percentage of the children and adolescent population, contributing to decreased quality of life and increased risk for comorbidities. Although the major causes of obesity are known, the obesogenic behaviors manifest…
Rheumatoid arthritis is a chronic autoimmune disease that is a major public health challenge. The disease is characterised by inflammation of synovial joints and cartilage erosion, which leads to chronic pain, poor life quality and, in some…
Myopia is a common visual disorder that affects millions of people worldwide and its prevalence has been increasing in recent years. Environmental factors, such as reading time, viewing distance, and ambient lighting, have been identified…
Many interesting shapes appearing in the biological world are formed by the onset of mechanical instability. In this work we consider how the build-up of residual stress can cause a solid to buckle. In all past studies a fictitious…