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A geometric mechanism that may, in analogy to similar notions in physics, be considered as "symmetry breaking" in geometry is described, and several instances of this mechanism in differential geometry are discussed: it is shown how…

Differential Geometry · Mathematics 2022-06-28 Andreas Fuchs , Udo Hertrich-Jeromin , Mason Pember

The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. While the biochemical details of this code were unraveled long ago, its origin is still obscure. We review information-theoretic approaches to the…

Genomics · Quantitative Biology 2010-07-23 Tsvi Tlusty

A semi-classical model for wobbling motion is presented as an extension to the Bohr-Mottelson model of wobbling motion. Using the resultant wobbling potential, a quantum mechanical equation is derived for anharmonic wobbling motion. We then…

Nuclear Theory · Physics 2009-11-11 Makito Oi

The genome is software because it a set of verbal instructions for a programmable computer, the ribosome. The theory of evolution now reads: evolution is the software developer responsible for the existence of the genome. We claim that this…

Other Quantitative Biology · Quantitative Biology 2010-03-03 Jose Rodriguez

A triaxial rotor Hamiltonian with a rigidly aligned high-$j$ quasiparticle is treated by a time-dependent variational principle, using angular momentum coherent states. The resulting classical energy function have three unique critical…

Nuclear Theory · Physics 2018-02-07 R. Budaca

A very simple model for cell swelling by osmosis is introduced, resulting in a parabolic free boundary problem. In case of radially symmetric initial conditions, it is shown that the model can be viewed as a gradient flow involving entropy,…

Dynamical Systems · Mathematics 2013-02-05 Martijn Zaal

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

The mechanism of spontaneous symmetry breaking in quantum systems is briefly reviewed, rectifying part of the standard wisdom on logical and mathematical grounds. The crucial role of the localization properties of the time evolution for the…

History and Philosophy of Physics · Physics 2012-01-27 F. Strocchi

The next step in the understanding of the genome organization, after the determination of complete sequences, involves proteomics. The proteome includes the whole set of protein-protein interactions, and two recent independent studies have…

Statistical Mechanics · Physics 2007-05-23 Ricard V. Sole , Romualdo Pastor-Satorras , Eric Smith , Thomas B. Kepler

We study the oscillatory behaviour of a gene regulatory network with interlinked positive and negative feedback loop. Frequency and amplitude are two important properties of oscillation. Studied network produces two different modes of…

Molecular Networks · Quantitative Biology 2015-12-21 Rajesh Karmakar

We show that very small-amplitude oscillations of a highly symmetric, spheric or cylindrical, interface (thin membrane) between two fluids can result in inhomogeneous instability and breaking of the interface symmetry: the frequency of the…

Fluid Dynamics · Physics 2007-05-23 N. Garcia , V. V. Osipov

We examine the issue of stability of probability in reasoning about complex systems with uncertainty in structure. Normally, propositions are viewed as probability functions on an abstract random graph where it is implicitly assumed that…

Artificial Intelligence · Computer Science 2017-12-14 Subhash Kak

Concomitant with the evolution of biological diversity must have been the evolution of mechanisms that facilitate evolution, due to the essentially infinite complexity of protein sequence space. We describe how evolvability can be an object…

Populations and Evolution · Quantitative Biology 2009-11-10 David J. Earl , Michael W. Deem

A body dissipates energy when it freely rotates about any axis different from principal. This entails relaxation, i.e., decrease of the rotational energy, with the angular momentum preserved. The spin about the major-inertia axis…

Astrophysics · Physics 2014-10-13 Michael Efroimsky

We investigate the problem of determining the shape of a rotating celestial object - e.g., a comet or an asteroid - under its own gravitational field. More specifically, we consider an object symmetric with respect to one axis - such as a…

Earth and Planetary Astrophysics · Physics 2021-03-24 Wai-Ting Lam , Marian Gidea , Fredy R Zypman

The buckling of a soft elastic sample under growth or swelling has highlighted a new interest in materials science, morphogenesis, and biology or physiology. Indeed, the change of mass or volume is a common fact of any living species, and…

Soft Condensed Matter · Physics 2023-09-21 Martine Ben Amar

The orientation of a rigid object can be described by a rotation that transforms it into a standard position. For a symmetrical object the rotation is known only up to multiplication by an element of the symmetry group. Such ambiguous…

Statistics Theory · Mathematics 2017-01-09 R. Arnold , P. E. Jupp , H. Schaeben

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Dynamical Systems · Mathematics 2015-02-26 Marco Villani , Davide Campioli , Chiara Damiani , Andrea Roli , Alessandro Filisetti , Roberto Serra

A central biological question is how natural organisms are so evolvable (capable of quickly adapting to new environments). A key driver of evolvability is the widespread modularity of biological networks--their organization as functional,…

Populations and Evolution · Quantitative Biology 2015-03-13 Jeff Clune , Jean-Baptiste Mouret , Hod Lipson

The majority of current phylogenetic comparative methods assume that the stochastic evolutionary process is homogeneous over the phylogeny or offer relaxations of this in rather limited and usually parameter expensive ways. Here we make a…

Populations and Evolution · Quantitative Biology 2014-03-07 Krzysztof Bartoszek