Related papers: Wobbling of What?
A quantitative theory on the construction and the evolution of the genetic code is proposed. Through introducing the concept of mutational deterioration (MD) and developing a theoretical formalism on MD minimization we have proved: 1, the…
We describe the theoretical ideas, developed between the 1950s-1970s, which led to the prediction of the Higgs boson, the particle that was discovered in 2012. The forces of nature are based on symmetry principles. We explain the nature of…
Research in quantitative evolutionary genomics and systems biology led to the discovery of several universal regularities connecting genomic and molecular phenomic variables. These universals include the log-normal distribution of the…
The question of whether charged leptons oscillate is discussed in detail, with a special emphasis on the coherence properties of the charged lepton states created via weak interactions. This analysis allows one to clarify also an important…
In this note we outline the history of q-deformations; indicate their physical shortcomings; suggest their apparent resolution via an invariant formulation based on a new mathematics of genotopic type; and point out their expected physical…
General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…
Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…
A possible causal solution to the problem of providing a spacetime description of the transmission of signals in quantum entangled states is described using a `bimetric' spacetime structure, in which the quantum entanglement measurements…
Natural protein sequences contain a record of their history. A common constraint in a given protein family is the ability to fold to specific structures, and it has been shown possible to infer the main native ensemble by analyzing…
Many open problems in biology, as in the physical sciences, display nonlinear and 'chaotic' dynamics, which, to the extent possible, cannot be reasonably understood. Moreover, mathematical models which aim to predict/estimate unknown…
The development of new techniques to quantitatively measure gene expression in cells has shed light on a number of systems that display oscillations in protein concentration. Here we review the different mechanisms which can produce…
A novel mechanism for sympatric speciation that takes into account complex bio-processes within each individual organism is proposed. According to dynamical systems theory, organisms with identical genotypes can possess differentiated…
A random matrix model to describe the coupling of m-fold symmetry in constructed. The particular threefold case is used to analyze data on eigenfrequencies of elastomechanical vibration of an anisotropic quartz block. It is suggested that…
Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…
Well known Simpson's paradox is puzzling and surprising for many, especially for the empirical researchers and users of statistics. However there is no surprise as far as mathematical details are concerned. A lot more is written about the…
We present a theory characterizing the phases emerging as a consequence of continuous symmetry-breaking in quantum and classical systems. In symmetry-breaking phases, dynamics is restricted due to the existence of a set of conserved charges…
We study a stochastic model proposed recently in the genetic literature to explain the heterogeneity of cell populations or of gene products. Cells are located in two colonies, whose sizes fluctuate as birth and migration processes in…
A codon table is a useful tool for mapping codons to amino acids as they have been assigned by nature. It has become a scientific icon because of the way it embodies our understanding of this natural process and the way it immediately…
Proteins fold using a two-state or multi-state kinetic mechanisms, but up to now there isn't a first-principle model to explain this different behaviour. We exploit the network properties of protein structures by introducing novel…
Although osmosis is a familiar phenomenon, and of pivotal importance in natural systems, it is seldom explained how it might work on the molecular level (if treated at all in physics text books). The standard treatment of osmosis in…