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The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve…

Biosensor data has the potential ability to improve disease control and detection. However, the analysis of these data under free-living conditions is not feasible with current statistical techniques. To address this challenge, we introduce…

Applications · Statistics 2021-03-30 Marcos Matabuena , Alexander Petersen , Juan C. Vidal , Francisco Gude

Oral Glucose Tolerance Test (OGTT) is one of many way to produce data in the study of the diabetes dynamic. In a recent paper [1.]:\textit{ Estimating insulin sensitivity and $ \beta $-cell function from the oral glucose tolerance test:…

Probability · Mathematics 2024-12-17 Paul Bekima

Due to their photonic components, exciton-polariton systems provide a convenient platform to study the coherence properties of weakly-interacting Bose gases. In particular, optical interferometry enables the measurement of the first-order…

Quantum Gases · Physics 2025-09-05 Joseph Jachinowski , Hassan Alnatah , David W. Snoke , Peter B. Littlewood

Studying the internal structure of complex samples with light is an important task, but a difficult challenge due to light scattering. While the complex optical distortions induced by multiple scattering can be effectively undone with the…

Optics · Physics 2019-10-04 Ori Katz , François Ramaz , Sylvain Gigan , Mathias Fink

This short textbook was written for someone who newly start studying, doing research, or development about optical coherence tomography (OCT) or using OCT. The first chapter summarizes the concept and the history of OCT. In the second…

Medical Physics · Physics 2022-12-09 Yoshiaki Yasuno

Multispectral imaging (MSI) can provide information about tissue oxygenation, perfusion and potentially function during surgery. In this paper we present a novel, near real-time technique for intrinsic measurements of total haemoglobin…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Geoffrey Jones , Neil T. Clancy , Yusuf Helo , Simon Arridge , Daniel S. Elson , Danail Stoyanov

In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The…

Optics · Physics 2021-01-07 Antoine Boniface , Jonathan Dong , Sylvain Gigan

We propose an original adaptive wavefront holographic setup based on the photorefractive effect (PR), to make real-time measurements of acousto-optic signals in thick scattering media, with a high flux collection at high rates for breast…

The squeezed photons, as a quantum-correlated light with reduced noise, have emerged as a great resource for sensing the structures of matter. Here we study the transient absorption (TA) scheme using the squeezed photons whose spectral…

Quantum Physics · Physics 2026-05-29 Jiahao Joel Fan , Feihong Liu , Dangyuan Lei , Zhedong Zhang

We present a new interferometric technique for measuring Coherent Anti-Stokes Raman Scattering (CARS) and Second Harmonic Generation (SHG) signals. Heterodyne detection is employed to increase the sensitivity in both CARS and SHG signal…

Optics · Physics 2009-11-10 C. Vinegoni , J. S. Bredfeldt , D. L. Marks , S. A. Boppart

We propose and experimentally demonstrate temporally low-coherent optical diffraction tomography (ODT) based on angle-scanning Mach-Zehnder interferometry. Using a digital micromirror device based on diffractive tilting, we successfully…

Optics · Physics 2018-07-17 KyeoReh Lee , Seungwoo Shin , Zahid Yaqoob , Peter T. C. So , YongKeun Park

Optical scattering presents a major obstacle to high resolution imaging in biological tissue and other turbid media. Conventional photoacoustic imaging can partially overcome this obstacle, enabling imaging of optical absorption in the…

Established x-ray diffraction methods allow for high-resolution structure determination of crystals, crystallized protein structures or even single molecules. While these techniques rely on coherent scattering, incoherent processes like…

Second-harmonic scattering experiments of water and other bulk molecular liquids have long been assumed to be insensitive to interactions between the molecules. The measured intensity is generally thought to arise from incoherent scattering…

Soft Condensed Matter · Physics 2017-08-28 Gabriele Tocci , Chungwen Liang , David M. Wilkins , Sylvie Roke , Michele Ceriotti

Using optical speckle scanning microscopy [1], we demonstrate that clear images of multiple cells can be obtained through biological scattering tissue, with subcellular resolution and good image quality, as long as the size of the imaging…

Optics · Physics 2023-07-19 Xin Yang , Ye Pu , Demetri Psaltis

Entanglement is a key resource in quantum technologies, enhancing precision and resolution in imaging and sensing by leveraging the cross-correlation of photon pairs. This correlation enables precise time synchronization of photons reaching…

Strong quantum-correlated sources are essential but delicate resources for quantum information science and engineering protocols. Decoherence and loss are the two main disruptive processes that lead to the loss of nonclassical behavior in…

Optical absorption measurements characterize a wide variety of systems from atomic gases to \emph{in-vivo} diagnostics of living organisms. Here we study the potential of non-classical techniques to reduce statistical noise below the…

Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced…

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