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A device based on Polarization sensitive optical coherence tomography is developed to monitor blood glucose levels in human subjects. The device was initially tested with tissue phantom. The measurements with human subjects for various…

Biological Physics · Physics 2015-06-04 Jitendra Solanki , OM Prakash Choudhury , Pratima Sen , Joseph Thomas Andrews

The utility of optical coherence tomography signal intensity for measurement of glucose concentration has been analysed in tissue phantom and blood samples from human subjects. The diffusion equation based calculations as well as in-vivo…

Medical Physics · Physics 2012-01-24 Jitendra Solanki , Pratima Sen , Joseph Thomas Andrews , Kamal Kishore Thareja

Diabetes mellitus is a complex group of syndromes that have in common a disturbance in the body's use of glucose, resulting in an elevated blood sugar. Once detected, sugar diabetes can be controlled by an appropriate regimen that should…

Medical Physics · Physics 2008-11-03 Raju Poddar , Joseph Thomas Andrews , Pratyoosh Shukla , Pratima Sen

This work demonstrates a non-contact diffuse reflectance approach with a working distance of ~1.1 meters for the potential of glucose sensing. Non-contact diffuse reflectance over 1.1-1.3 micrometers was developed according to a…

Medical Physics · Physics 2020-09-03 Daqing Piao , John O'Hara , Satish Bukkapatnam , Sabit Ekin

Glucometers present an important self-monitoring tool for diabetes patients and therefore must exhibit high accu- racy as well as good usability features. Based on an invasive, photometric measurement principle that drastically reduces the…

Applications · Statistics 2016-02-11 Nevine Demitri , Abdelhak M. Zoubir

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

Medical Physics · Physics 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Effective diabetes management relies heavily on the continuous monitoring of blood glucose levels, traditionally achieved through invasive and uncomfortable methods. While various non-invasive techniques have been explored, such as optical,…

Machine Learning · Computer Science 2024-08-16 Nihat Ahmadli , Mehmet Ali Sarsil , Onur Ergen

Diabetes is one of the most debilitating and costly diseases currently plaguing humanity. It is a leading cause of death and dismemberment in the world, and we know how to treat it. Accurate, continuous monitoring and control of blood…

Biological Physics · Physics 2016-01-25 Brett H. Hokr , Carlos E. Tovar , Zhaokai Meng , Georgi I. Petrov , Vladislav V. Yakovlev

Optical coherence tomography (OCT) is a widely used imaging technique in the micrometer regime, which gained accelerating interest in medical imaging in the last twenty years. In up-to-date OCT literature [5,6] certain simplifying…

Medical Physics · Physics 2024-02-23 Leopold Veselka , Lisa Krainz , Leonidas Mindrinos , Wolfgang Drexler , Peter Elbau

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

Medical Physics · Physics 2020-07-31 Viacheslav Mazlin , Kristina Irsch , Michel Paques , Mathias Fink , Albert Claude Boccara

In this work, the blood NIR absorbances are recorded using the FT-IR method. It is shown that when the absorbance curves are multiplied by the first derivative of the water absorbance spectrum as well as by the first derivative of the…

Medical Physics · Physics 2025-07-22 Hadi Barati , Arian Mousavi Madani , Soheil Moradi , Mehdi Fardmanesh

Glucose monitoring plays a critical role in managing diabetes, one of the most prevalent diseases globally. The development of fast-responsive, cost-effective, and biocompatible glucose sensors is essential for improving patient care. In…

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…

Quantitative Methods · Quantitative Biology 2024-12-05 Xiaoyu Yin , Elisabetta Peri , Eduard Pelssers , Jaap den Toonder , Lisa Klous , Hein Daanen , Massimo Mischi

Diabetes is a chronicle disease where the body of a human is irregular to dissolve the blood glucose properly. The diabetes is due to lack of insulin in human body. The continuous monitoring of blood glucose is main important aspect for…

Medical Physics · Physics 2021-06-10 Prateek Jain , Amit M. Joshi , Saraju Mohanty

An algorithm based on PLS regression has been developed and optimized for measuring blood glucose level using the infra-red transmission spectrum of blood samples. A set of blood samples were tagged with their glucose concentration using an…

Quantitative Methods · Quantitative Biology 2018-04-11 Afarin Aghassizadeh , Mohammad Reza Nematollahi , Iman Mirzaie , Mehdi Fardmanesh

In the U.S., over a third of adults are pre-diabetic, with 80\% unaware of their status. This underlines the need for better glucose monitoring to prevent type 2 diabetes and related heart diseases. Existing wearable glucose monitors are…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Yidong Zhu , Nadia B Aimandi , Mohammad Arif Ul Alam

Optical coherence tomography (OCT) is a powerful biomedical imaging technology that relies on the coherent detection of backscattered light to image tissue morphology in vivo. As a consequence, OCT is susceptible to coherent noise (speckle…

A new approach for continuous and non-invasive monitoring of the glucose concentration in human epidermis has been suggested recently. This method is based on photoacoustic (PA) analysis of human interstitial fluid. The measurement can be…

Computational Physics · Physics 2015-07-21 Bernd Baumann , Marcus Wolff , Mark Teschner

We demonstrate optical coherence tomography based on an SU(1,1) nonlinear interferometer with high-gain parametric down-conversion. For imaging and sensing applications, this scheme promises to outperform previous experiments working at low…

Quantum Physics · Physics 2020-08-31 Gerard J. Machado , Gaetano Frascella , Juan P. Torres , Maria V. Chekhova
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