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Gene regulatory networks constitute the first layer of the cellular computation for cell adaptation and surveillance. In these webs, a set of causal relations is built up from thousands of interactions between transcription factors and…

Molecular Networks · Quantitative Biology 2009-11-30 Carlos Rodriguez-Caso , Bernat Corominas-Murtra , Ricard V. Solé

A fundamental question in neuroscience is how structure and function of neural systems are related. We study this interplay by combining a familiar auto-associative neural network with an evolving mechanism for the birth and death of…

Adaptation and Self-Organizing Systems · Physics 2019-04-26 Ana P. Millán , J. J. Torres , S. Johnson , J. Marro

Systems as diverse as genetic networks or the world wide web are best described as networks with complex topology. A common property of many large networks is that the vertex connectivities follow a scale-free power-law distribution. This…

Disordered Systems and Neural Networks · Physics 2015-06-25 Albert-Laszlo Barabasi , Reka Albert

Systems composed of distinct complex networks are present in many real-world environments, from society to ecological systems. In the present paper, we propose a network model obtained as a consequence of interactions between two species…

Biological Physics · Physics 2007-08-08 Luis Enrique Correa da Rocha , Luciano da Fontoura Costa

A cell's behavior is a consequence of the complex interactions between its numerous constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling pathways and regulatory mechanisms to coordinate multiple processes,…

Molecular Networks · Quantitative Biology 2007-09-12 Reka Albert

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

Neurons and Cognition · Quantitative Biology 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

Horizontal gene transfer (HGT) is an important process in bacterial evolution. Current phylogeny-based approaches to capture it cannot however appropriately account for the fact that HGT can occur between bacteria living in different…

Populations and Evolution · Quantitative Biology 2025-03-31 Katharina T. Huber , Darren Overman

We propose a growing network model that consists of two tunable mechanisms: growth by merging modules which are represented as complete graphs and a fitness-driven preferential attachment. Our model exhibits the three prominent statistical…

Molecular Networks · Quantitative Biology 2007-07-31 Kazuhiro Takemoto , Chikoo Oosawa

Social networks exhibit strikingly systematic patterns across a wide range of human contexts. While genetic variation accounts for a significant portion of the variation in many complex social behaviors, the heritability of egocentric…

Genomics · Quantitative Biology 2009-02-11 James H. Fowler , Christopher T. Dawes , Nicholas A. Christakis

Like a rocket being propelled into space, evolution has engineered flies to launch into adulthood via multiple stages. Flies develop and deploy two distinct bodies, linked by the transformative process of metamorphosis. The fly larva is a…

Neurons and Cognition · Quantitative Biology 2022-01-12 Sweta Agrawal , John C Tuthill

Food webs are networks describing who is eating whom in an ecological community. By now it is clear that many aspects of food-web structure are reproducible across diverse habitats, yet little is known about the driving force behind this…

Populations and Evolution · Quantitative Biology 2007-05-23 A. G. Rossberg , H. Matsuda , T. Amemiya , K. Itoh

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

Transport networks, such as vasculature or river networks, provide key functions in organisms and the environment. They usually contain loops whose significance for the stability and robustness of the network is well documented. However,…

Genes communicate with each other through different regulatory effects, which lead to the emergence of complex structures in cells, and such structures are expected to be different for normal and cancerous cells. To study breast cancer…

Molecular Networks · Quantitative Biology 2020-10-13 Abbas Karimi Rizi , Mina Zamani , Amirhossein Shirazi , G. Reza Jafari , János Kertész

Phylogenetic networks are used in biology to represent evolutionary histories. The class of orchard phylogenetic networks was recently introduced for their computational benefits, without any biological justification. Here, we show that…

Combinatorics · Mathematics 2021-10-22 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami

Understanding the origins of complexity is a fundamental challenge with implications for biological and technological systems. Network theory emerges as a powerful tool to model complex systems. Networks are an intuitive framework to…

Disordered Systems and Neural Networks · Physics 2024-10-22 Blai Vidiella , Salva Duran-Nebreda , Sergi Valverde

Phylogenetic networks which are, as opposed to trees, suitable to describe processes like hybridization and horizontal gene transfer, play a substantial role in evolutionary research. However, while non-treelike events need to be taken into…

Populations and Evolution · Quantitative Biology 2022-07-06 Mareike Fischer , Tom Niklas Hamann , Kristina Wicke

Genetic regulation is a key component in development, but a clear understanding of the structure and dynamics of genetic networks is not yet at hand. In this work we investigate these properties within an artificial genome model originally…

Molecular Networks · Quantitative Biology 2008-05-01 Thimo Rohlf , Chris Winkler

In this paper, we propose an evolving network model growing fast in units of module, based on the analysis of the evolution characteristics in real complex networks. Each module is a small-world network containing several interconnected…

Physics and Society · Physics 2011-10-11 Zou Zhi-Yun , Liu Peng , Lei Li , Gao Jian-Zhi

Complex networks from such different fields as biology, technology or sociology share similar organization principles. The possibility of a unique growth mechanism promises to uncover universal origins of collective behaviour. In…

Disordered Systems and Neural Networks · Physics 2009-09-29 Chaoming Song , Shlomo Havlin , Hernán A. Makse
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