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Neural networks show a progressive increase in complexity during the time course of evolution. From diffuse nerve nets in Cnidaria to modular, hierarchical systems in macaque and humans, there is a gradual shift from simple processes…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser , Sreedevi Varier

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

Recently, plenty research has been done on discovering the role of energy dissipation in biological networks, most of which focus on the relationship of dissipation and functionality. However, the development of networks science urged us to…

Biological Physics · Physics 2026-05-20 Bowen Shi , Long Qian , Qi Ouyang

Regulatory interactions between genes show a large amount of cross-species variability, even when the underlying functions are conserved: There are many ways to achieve the same function. Here we investigate the ability of regulatory…

Molecular Networks · Quantitative Biology 2015-05-13 Franck Stauffer , Johannes Berg

Phylogenetic networks are increasingly used in evolutionary biology to represent the history of species that have undergone reticulate events such as horizontal gene transfer, hybrid speciation and recombination. One of the most fundamental…

Populations and Evolution · Quantitative Biology 2016-10-07 Philippe Gambette , Leo van Iersel , Steven Kelk , Fabio Pardi , Celine Scornavacca

A central goal of evolutionary biology is to explain the origins and distribution of diversity across life. Beyond species or genetic diversity, we also observe diversity in the circuits (genetic or otherwise) underlying complex functional…

Populations and Evolution · Quantitative Biology 2018-06-06 Ali Tehrani-Saleh , Thomas LaBar , Christoph Adami

Phylogenetic networks represent evolutionary history of species and can record natural reticulate evolutionary processes such as horizontal gene transfer and gene recombination. This makes phylogenetic networks a more comprehensive…

Populations and Evolution · Quantitative Biology 2021-06-15 Remie Janssen , Pengyu Liu

In biological evolution complex neural structures grow from a handful of cellular ingredients. As genomes in nature are bounded in size, this complexity is achieved by a growth process where cells communicate locally to decide whether to…

Neural and Evolutionary Computing · Computer Science 2024-05-15 Eleni Nisioti , Erwan Plantec , Milton Montero , Joachim Winther Pedersen , Sebastian Risi

We study the evolution of the network properties of a populated network embedded in a genotype space characterised by either a low or a high number of potential links, with particular emphasis on the connectivity and clustering. Evolution…

Statistical Mechanics · Physics 2007-05-23 Paul Anderson , Henrik Jeldtoft Jensen

Phylogenetic networks are notoriously difficult to reconstruct. Here we suggest that it can be useful to view unknown genetic distance along edges in phylogenetic networks as analogous to unknown resistance in electric circuits. This…

Combinatorics · Mathematics 2020-10-01 Stefan Forcey , Drew Scalzo

A common trait of complex systems is that they can be represented by means of a network of interacting parts. It is, in fact, the network organisation (more than the parts) what largely conditions most higher-level properties, which are not…

Populations and Evolution · Quantitative Biology 2019-07-15 Ricard Sole , Sergi Valverde

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

There are diverse mechanisms driving the evolution of social networks. A key open question dealing with understanding their evolution is: How various preferential linking mechanisms produce networks with different features? In this paper we…

Physics and Society · Physics 2015-06-12 Haibo Hu , Jinli Guo , Xuan Liu

The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

Neurons and Cognition · Quantitative Biology 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

Complex dynamical systems are often modeled as networks, with nodes representing dynamical units which interact through the network's links. Gene regulatory networks, responsible for the production of proteins inside a cell, are an example…

Statistical Mechanics · Physics 2009-09-30 Zoran Levnajić

In evolutionary biology, phylogenetic networks are graphs that provide a flexible framework for representing complex evolutionary histories that involve reticulate evolutionary events. Recently phylogenetic studies have started to focus on…

Populations and Evolution · Quantitative Biology 2025-11-17 Niels Holtgrefe , Katharina T. Huber , Leo van Iersel , Mark Jones , Vincent Moulton

The structure of ecological networks, in particular food webs, determines their ability to evolve further, i.e. evolvability. The knowledge about how food web evolvability is determined by the structures of diverse ecological networks can…

Populations and Evolution · Quantitative Biology 2015-07-13 Jianxi Luo

The evolutionary relationships among organisms have traditionally been represented using rooted phylogenetic trees. However, due to reticulate processes such as hybridization or lateral gene transfer, evolution cannot always be adequately…

Populations and Evolution · Quantitative Biology 2022-01-20 Sungsik Kong , Joan Carles Pons , Laura Kubatko , Kristina Wicke

Genetic regulatory networks with adaptive responses are widely studied in biology. Usually, models consisting only of a few nodes have been considered. They present one input receptor for activation and one output node where the adaptive…

Molecular Networks · Quantitative Biology 2016-07-20 Pablo Kaluza , Masayo Inoue