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Nonlinear optical methods, such as coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS), are able to perform label free imaging, with chemical bonds specificity. Here, we demonstrate that the use of circularly…

We have developed an interferometric implementation of coherent anti-Stokes Raman scattering (CARS) which enables broadband coherent Raman spectroscopy free from non-resonant background (NRB), with a signal strength proportional to…

Optics · Physics 2014-02-25 Brad Littleton , Thomas Kavanagh , Frederic Festy , David Richards

Coherent Anti Stokes Raman Scattering (CARS) offers many advantages for nonlinear bio-imaging, thanks to its sub-cellular spatial resolution and unique chemical specificity. Its working principle requires two incident pulsed laser beams…

Single-shot time resolved Coherent Anti-Stokes Raman Scattering (CARS) is presented as a viable method for fast measurements of molecular spectra. The method is based on the short spatial extension of femtosecond pulses and maps time delays…

Optics · Physics 2009-11-13 Yuri Paskover , I. Sh. Averbukh , Yehiam Prior

Since its first demonstration in the sixties, coherent anti-Stokes Raman scattering (CARS) has become a powerful spectroscopic sensing tool with broad applications in biology and chemistry. However, it is a complex nonlinear optical process…

Optics · Physics 2020-07-15 Gombojav O. Ariunbold , Supriya Nagpal , Bryan Semon

We present super-resolved coherent anti-Stokes Raman scattering (CARS) microscopy by implementing phase-resolved image scanning microscopy (ISM), achieving up to two-fold resolution increase as compared with a conventional CARS microscope.…

Optics · Physics 2024-11-22 Anna Zhitnitsky , Elad Benjamin , Ora Bitton , Dan Oron

We propose a Bayesian statistical model for analyzing coherent anti-Stokes Raman scattering (CARS) spectra. Our quantitative analysis includes statistical estimation of constituent line-shape parameters, underlying Raman signal,…

Applications · Statistics 2020-05-15 Teemu Härkönen , Lassi Roininen , Matthew T. Moores , Erik M. Vartiainen

We show that the increasingly popular nonlinear optical technique of time-domain coherent anti-Stokes Raman scattering (CARS), which is usually understood in terms of the semiclassical time-dependent third-order polarization, can be equally…

Optics · Physics 2014-06-03 Michele Marrocco

A new interferometric technique is demonstrated for measuring Coherent Anti-Stokes Raman Scattering (CARS) signals. Two forward-directed CARS signals are generated, one in each arm of an interferometer. The deterministic nature of the CARS…

Optics · Physics 2007-05-23 J. S. Bredfeldt , D. L. Marks , C. Vinegoni , S. Hambir , S. A. Boppart

Coherent anti-Stokes Raman scattering (CARS) spectroscopy with time-delayed ultrashort pulses and a single-pixel photodetector has shown great potential for spectroscopic imaging and transient studies in chemistry and biological research.…

Optics · Physics 2023-12-05 Tianjian Lv , Bing Han , Ming Yan , Zhaoyang Wen , Kun Huang , Kangwen Yang , Heping Zeng

Optical spectroscopy and imaging of microscopic samples have opened up a wide range of applications throughout the physical, chemical, and biological sciences. High chemical specificity may be achieved by directly interrogating the…

Coherent anti-Stokes Raman scattering (CARS) microspectroscopy has demonstrated significant potential for biological and materials imaging. To date, however, the primary mechanism of disseminating CARS spectroscopic information is through…

Optics · Physics 2015-10-08 Charles H. Camp , Young Jong Lee , Marcus T. Cicerone

We demonstrate coherent anti-Stokes Raman scattering (CARS) microscopy with 1089 foci, enabled by a high repetition rate amplified oscillator and optical parametric amplifier. We employ a camera as multichannel detector to acquire and…

Optics · Physics 2024-08-27 Dominykas Gudavicius , Lukas Kontenis , Wolfgang Langbein

We demonstrate an approach for background-free three-dimensional imaging of director fields in liquid crystals using stimulated Raman scattering microscopy. This imaging technique is implemented using a single femtosecond pulsed laser and a…

Soft Condensed Matter · Physics 2017-01-25 Taewoo Lee , Haridas Mundoor , Derek G. Gann , Timothy J. Callahan , Ivan I. Smalyukh

Surface-enhanced coherent anti-Stokes Raman scattering (SE-CARS) takes advantage of surface plasmon resonances supported on metallic nanostructures to amplify the coherent Raman response of target molecules. While these metallic antennas…

Optics · Physics 2022-09-07 Shamsul Abedin , Yong Li , Abid Anjum Sifat , Khokan Roy , Eric Olaf Potma

Coherent anti-Stokes Raman Spectroscopy (CARS) is a laser-based measurement technique widely applied across many science and engineering disciplines to perform non-intrusive gas diagnostics. CARS is often used to study combustion, where the…

Machine Learning · Computer Science 2022-05-25 Gregory J. Hunt , Cody R. Ground , Andrew D. Cutler

Coherent anti-Stokes Raman scattering (CARS) microscope system was built and applied to a non-intrusive gas concentration measurement of a mixing flow in a millimeter-scale channel. Carbon dioxide and nitrogen were chosen as test fluids and…

Fluid Dynamics · Physics 2015-08-07 Ken Yamamoto , Yuki Yamagata , Madoka Moriya , Reiko Kuriyama , Yohei Sato

We propose a full-vectorial numerical study of far field radiation patterns in coherent anti-Stokes Raman scattering (CARS) microscopy. We emphasis the particular role of the Raman depolarisation ratio of the observed medium and show how it…

Optics · Physics 2009-11-13 D. Gachet , N. Sandeau , H. Rigneault

Coherent anti-Stokes Raman scattering is a widely used imaging technique that provides chemical contrast without the need for labels, making it an extremely valuable tool in physics, chemistry, and biology. In this work, we explore its…

Quantum Physics · Physics 2025-08-05 Giacomo Sorelli , Manuel Gessner , Frank Schlawin

We have developed a coherent Raman imaging platform using broadband coherent anti-Stokes Raman scattering (BCARS) that provides an unprecedented combination of speed, sensitivity, and spectral breadth. The system utilizes a unique…

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