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Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

Soft Condensed Matter · Physics 2015-03-17 Florian Janoschek , Federico Toschi , Jens Harting

Virtual reality simulation has become a popular approach for training and assessing medical students. It offers diverse scenarios, realistic visuals, and quantitative performance metrics for objective evaluation. However, creating these…

Software Engineering · Computer Science 2023-11-27 Vladimir Poliakov , Dzmitry Tsetserukou , Emmanuel Vander Poorten

Complex systems are often decomposed into modular subsystems for engineering tractability. Although various equation based white-box modeling techniques make use of such structure, learning based methods have yet to incorporate these ideas…

Machine Learning · Computer Science 2022-10-31 Jayesh K. Gupta , Sai Vemprala , Ashish Kapoor

As Large Language Models increasingly power role-playing applications, simulating patients has become a valuable tool for training counselors and scaling therapeutic assessment. However, prior work is fragmented: existing approaches rely on…

Computation and Language · Computer Science 2026-02-13 Sahand Sabour , TszYam NG , Minlie Huang

HEALPix is a Hierarchical, Equal Area, and iso-Latitude Pixelisation of the sphere designed to support efficiently - local operations on the pixel set, - a hierarchical tree structure for multi-resolution applications, and - the global Fast…

An efficient technique is introduced for model inference of complex nonlinear dynamical systems driven by noise. The technique does not require extensive global optimization, provides optimal compensation for noise-induced errors and is…

Data Analysis, Statistics and Probability · Physics 2007-05-23 V. N. Smelyanskiy , D. A. Timucin , A. Bandrivskyy , D. G. Luchinsky

To understand how well a proposed augmented reality (AR) solution works, existing papers often conducted tailored and isolated evaluations for specific AR tasks, e.g., depth or lighting estimation, and compared them to easy-to-setup…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-18 Ashkan Ganj , Yiqin Zhao , Federico Galbiati , Tian Guo

Neuromorphic control is receiving growing attention due to the multifaceted advantages it brings over more classical control approaches, including: sparse and on-demand sensing, information transmission, and actuation; energy-efficient…

Systems and Control · Electrical Eng. & Systems 2025-06-13 Taisia Medvedeva , Alessio Franci , Fernando Castaños

Pulmonary hypertension (PH), defined by a mean pulmonary arterial pressure (mPAP) $>$ 20 mmHg, is characterized by increased pulmonary vascular resistance and decreased pulmonary arterial compliance. There are few measurable biomarkers of…

Quantitative Methods · Quantitative Biology 2025-06-06 Amanda L. Colunga , Mitchel J. Colebank , REU Program , Mette S. Olufsen

Chronic Obstructive Pulmonary Disorder (COPD) is an irreversible and progressive disease which is highly heritable. Clinically, COPD is defined using the summary measures derived from a spirometry test but these are not always adequate.…

Machine Learning · Computer Science 2024-11-15 Soham Gadgil , Joshua Galanter , Mohammadreza Negahdar

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

In this chapter we introduce a combined parameter and model reduction methodology and present its application to the efficient numerical estimation of a pressure drop in a set of deformed carotids. The aim is to simulate a wide range of…

Numerical Analysis · Mathematics 2023-08-30 Marco Tezzele , Francesco Ballarin , Gianluigi Rozza

Model Order Reduction (MOR) can significantly reduce the computational cost of vibroacoustic simulations. While most MOR research focuses on single-domain systems (e.g., structural dynamics or computational fluid mechanics), this work…

Applied Physics · Physics 2026-02-05 Sander Metting van Rijn , Linus Taenzer , Paolo Tiso , Bart Van Damme

Quantum many-body systems undergoing phase transitions have been proposed as probes enabling beyond-classical enhancement of sensing precision. However, this enhancement is usually limited to a very narrow region around the critical point.…

Quantum Physics · Physics 2024-09-18 Chiranjib Mukhopadhyay , Abolfazl Bayat

A multi-scale framework was recently proposed for more realistic molecular dynamics simulations in continuum solvent models by coupling a molecular mechanics treatment of solute with a fluid mechanics treatment of solvent, where we…

Biological Physics · Physics 2018-01-17 Li Xiao , Ray Luo

Traditional control and task automation have been successfully demonstrated in a variety of structured, controlled environments through the use of highly specialized modeled robotic systems in conjunction with multiple sensors. However, the…

Robotics · Computer Science 2020-02-20 Yang Li , Florian Richter , Jingpei Lu , Emily K. Funk , Ryan K. Orosco , Jianke Zhu , Michael C. Yip

Hybrid particle-field methods are computationally efficient approaches for modelling soft matter systems. So far applications of these methodologies have been limited to constant volume conditions. Here, we reformulate particle-field…

Obstructive sleep apnea syndrome is now considered as a major health care topic. An in-vitro setup which reproduces and simplifies upper airway geometry has been the basis to study the fluid/walls interaction that leads to an apnea. It…

Medical Physics · Physics 2016-08-16 Franz Chouly , Annemie Van Hirtum , Pierre-Yves Lagrée , Xavier Pelorson , Yohan Payan

This paper describes the architecture and demonstrates the capabilities of a newly developed, physically-based imaging simulator environment called SISPO, developed for small solar system body fly-by and terrestrial planet surface mission…

We develop a multiscale hybrid scheme for simulations of soft condensed matter systems, which allows one to treat the system at the particle level in selected regions of space, and at the continuum level elsewhere. It is derived…

Soft Condensed Matter · Physics 2015-06-17 Shuanhu Qi , Hans Behringer , Friederike Schmid