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Related papers: Conformation of Circular DNA in 2 Dimensions

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Correlation length exponent $\nu$ for long linear DNA molecules was determined by direct measurement of the average end-to-end distance as a function of the contour length $s$ by means of atomic force microscopy (AFM). Linear DNA, up to…

Soft Condensed Matter · Physics 2009-11-11 Francesco Valle , Melanie Favre , Paolo De Los Rios , Angelo Rosa , Giovanni Dietler

We examine the conformations of a model for a short segment of closed DNA. The molecule is represented as a cylindrically symmetric elastic rod with a constraint corresponding to a specification of the linking number. We obtain analytic…

Soft Condensed Matter · Physics 2009-10-31 Boris Fain , Joseph Rudnick

The scaling properties of DNA knots of different complexities were studied by atomic force microscope. Following two different protocols DNA knots are adsorbed onto a mica surface in regimes of (i) strong binding, that induces a kinetic…

Chain-like macromolecules in solution, whether biological or synthetic, transform from a spatially extended conformation to a compact one upon change of temperature or solvent qualities. This sharp transition plays a key role in various…

Soft Condensed Matter · Physics 2007-05-23 H. Diamant , D. Andelman

We studied the electrical conductivity of DNA molecules with conducting atomic force microscopy as a function of the chemical nature of the substrate surfaces, the nature of the electrical contact, and the number of DNA molecules (from a…

Materials Science · Physics 2009-11-10 Thomas Heim , Dominique Deresmes , Dominique Vuillaume

The sequence-dependent elasticity of double-helical DNA on a nm length scale can be captured by the rigid base-pair model, whose strains are the relative position and orientation of adjacent base-pairs. Corresponding elastic potentials have…

Biomolecules · Quantitative Biology 2013-05-29 Nils B. Becker , Ralf Everaers

Studies of circular DNA confined to nanofluidic channels are relevant both from a fundamental polymer-physics perspective and due to the importance of circular DNA molecules in vivo. We here observe the unfolding of DNA from the circular to…

The ubiquitous biomacromolecule DNA has an axial rigidity persistence length of ~50 nm, driven by its elegant double helical structure. While double and multiple helix structures appear widely in nature, only rarely are these found in…

The interplay between global constraints and local material properties of chain molecules is a subject of emerging interest. Studies of molecules that are intrinsically chiral, such as double-stranded DNA, is one example. Their properties…

Biological Physics · Physics 2013-11-27 Jakob Bohr , Kasper W. Olsen

The helical coil is ubiquitous in biological and natural systems and often it is the basic form that leads to complex structures. This paper considers the question of its dimensionality in biological information as the helical coil goes…

Biological Physics · Physics 2024-07-04 Subhash Kak

The behavior of long DNA molecules in a cell-sized confined space was investigated. We prepared water-in-oil droplets covered by phospholipids, which mimic the inner space of a cell, following the encapsulation of DNA molecules with…

Biological Physics · Physics 2015-04-14 T. Hamada , R. Fujimoto , S. F. Shimobayashi , M. Ichikawa , M. Takagi

A simple model of a circularly closed dsDNA in a poor solvent is considered as an example of a semi-flexible polymer with self-attraction. To find the ground states, the conformational energy is computed as a sum of the bending and…

Biological Physics · Physics 2013-04-25 E. L. Starostin

We report a theoretical study of DNA flexibility and quantitatively predict the ring closure probability as a function of DNA contour length. Recent experimental studies show that the flexibility of short DNA fragments (as compared to the…

Soft Condensed Matter · Physics 2013-10-01 Xinliang Xu , Beng Joo Reginald , Jianshu Cao

The strength of the spin-orbit interaction relevant to transport in a low dimensional structure depends critically on the relative geometrical arrangement of current carrying orbitals. Recent tight-binding orbital models for spin transport…

Mesoscale and Nanoscale Physics · Physics 2017-10-20 Solmar Varela , Vladimiro Mujica , Ernesto Medina

We use an elastic rod model with contact to study the extension versus rotation diagrams of single supercoiled DNA molecules. We reproduce quantitatively the supercoiling response of overtwisted DNA and, using experimental data, we get an…

Biomolecules · Quantitative Biology 2013-05-29 Sebastien Neukirch

We examine the conformations of a model for under- and overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding to a specification of the link…

Soft Condensed Matter · Physics 2009-10-28 Boris Fain , Joseph Rudnick , Stellan Ostlund

Advanced Monte Carlo simulations are used to study the effect of nano-slit confinement on metric and topological properties of model DNA chains. We consider both linear and circularised chains with contour lengths in the 1.2--4.8 $\mu$m…

Biological Physics · Physics 2012-04-11 C. Micheletti , E. Orlandini

We investigate the melting transition of non-supercoiled circular DNA of different lengths, employing Brownian dynamics simulation. In the absence of supercoiling, we find that melting of circular DNA is driven by a large bubble, which…

Soft Condensed Matter · Physics 2024-10-14 Souradeep Sengupta , Somendra M. Bhattacharjee , Garima Mishra

We study the elastic behaviour of a supercoiled DNA molecule. The simplest model is that of a rod like chain, involving two elastic constants, the bending and the twist rigidities. We show that this model is singular and needs a small…

Condensed Matter · Physics 2009-10-31 Claude Bouchiat , Marc Mezard

The Kinetoplast DNA (kDNA) is a two-dimensional Olympic-ring-like network of mutually linked 2.5 kb-long DNA minicircles found in certain parasites called Trypanosomes. Understanding the self-assembly and replication of this structure are…

Soft Condensed Matter · Physics 2022-09-07 Pinyao He , Allard J. Katan , Luca Tubiana , Cees Dekker , Davide Michieletto
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