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Unusually high bending flexibility has been recently reported for DNA on short length scales. We use atomic force microscopy (AFM) in solution to obtain a direct estimate of DNA bending statistics for scales down to one helical turn. It…

Biomolecules · Quantitative Biology 2014-07-22 Alexey K. Mazur , Mounir Maaloum

We present micro-rheological measurments of the drag force on colloids pulled through a solution of lambda-DNA (used here as a monodisperse model polymer) with an optical tweezer. The experiments show a violation of the Stokes-Einstein…

Soft Condensed Matter · Physics 2009-11-13 Christof Gutsche , Friedrich Kremer , Matthias Krüger , Markus Rauscher , Rudolf Weeber , Jens Harting

In this work we first prove, by formal arguments, that the diffusion limit of nonlinear kinetic equations, where both the transport term and the turning operator are density-dependent, leads to volume-exclusion chemotactic equations. We…

Analysis of PDEs · Mathematics 2022-11-04 Gissell Estrada-Rodriguez , Diane Peurichard , Xinran Ruan

Although carbon nanotubes are potential candidates for DNA encapsulation and subsequent delivery of biological payloads to living cells, the thermodynamical spontaneity of DNA encapsulation under physiological conditions is still a matter…

Biological Physics · Physics 2016-05-05 Fernando J. A. L. Cruz , Juan J. de Pablo , José P. B. Mota

If a semiflexible polymer confined to a narrow channel bends around by 180 degrees, the polymer is said to exhibit a hairpin. The equilibrium extension statistics of the confined polymer are well understood when hairpins are vanishingly…

A variety of viruses tightly pack their genetic material into protein capsids that are barely large enough to enclose the genome. In particular, in bacteriophages, forces as high as 60 pN are encountered during packaging and ejection,…

We use Monte Carlo simulations to study attractive and excluded volume interactions between nucleosome core particles in 30 nm-chromatin fibers. The nucleosomes are treated as disk-like objects having an excluded volume and short range…

Subcellular Processes · Quantitative Biology 2009-11-10 Boris Mergell , Ralf Everaers , Helmut Schiessel

The unconstrained genomic DNA of bacteria forms a coil, which volume exceeds 1000 times the volume of the cell. Since prokaryotes lack a membrane-bound nucleus, in sharp contrast with eukaryotes, the DNA may consequently be expected to…

Biomolecules · Quantitative Biology 2015-09-09 Marc Joyeux

Electrokinetic transport behavior in nanochannels is different to that in larger sized channels. Specifically, molecular dynamics (MD) simulations in nanochannels have demonstrated two little understood phenomena which are not observed in…

Compressional properties of nuclear matter are studied by using the mean field theory with the excluded volume effects of the nucleons. It is found that the excluded volume effects make it possible to fit the empirical data of the Coulomb…

Nuclear Theory · Physics 2009-10-28 H. Kouno , K. Koide , T. Mitsumori , N. Noda , A. Hasegawa , M. Nakano

Information has an entropic character which can be analyzed within the Statistical Theory in molecular systems. R. Landauer and C.H. Bennett showed that a logical copy can be carried out in the limit of no dissipation if the computation is…

Biological Physics · Physics 2012-08-15 J. Ricardo Arias-Gonzalez

In tiny metallic nanostructures, quantum confinement and nonlocal response change the collective plasmonic behavior with important consequences for e.g. field-enhancement and extinction cross sections. We report on our most recent…

Optics · Physics 2012-09-07 N. A. Mortensen , G. Toscano , S. Raza , N. Stenger , W. Yan , A. -P. Jauho , S. Xiao , M. Wubs

Evolutionally conserved quantity that specifies folding nuclei is pursued by a case study for a small protein (PDB code: 1ten). First it is demonstrated that the sequences of amino acids at folding nuclei are not conserved. Then 3D…

Biological Physics · Physics 2007-05-23 S. Nakamura , O. Narikiyo

When DNA molecules are heated they denature. This occurs locally so that loops of molten single DNA strands form, connected by intact double-stranded DNA pieces. The properties of this "melting" transition have been intensively…

Biological Physics · Physics 2015-06-29 E. Werner , M. Reiter-Schad , T. Ambjörnsson , B. Mehlig

We investigate the solvation of methane and methane decorated with charges in spherically confined water droplets. Free energy profiles for a single methane molecule in droplets, ranging in diameter D, from 1 to 4 nm, show that the droplet…

Chemical Physics · Physics 2009-09-29 S. Vaitheeswaran , D. Thirumalai

Cross-sectional area and volume become difficult to define as material dimensions approach the atomic scale. This limits the transferability of macroscopic concepts such as Young's modulus. We propose a new volume definition where the…

Mesoscale and Nanoscale Physics · Physics 2013-03-20 Philipp Wagner , Viktoria V. Ivanovskaya , Mark J. Rayson , Patrick R. Briddon , Christopher P. Ewels

In a distributed information application an encoder compresses an arbitrary vector while a similar reference vector is available to the decoder as side information. For the Hamming-distance similarity measure, and when guaranteed perfect…

Information Theory · Computer Science 2020-09-08 Yuval Cassuto , Jacob Ziv

Entangled ring polymers, along with blends of ring and linear polymers, continue to be a topic of great interest and debate due to the conflicting experimental results in the literature as well as the difficulty of producing entangled…

Soft Condensed Matter · Physics 2020-05-27 K. R. Peddireddy , M. Lee , C. M. Schroeder , R. M. Robertson-Anderson

We present a general theory for predicting the interaction potentials between DNA-coated colloids, and more broadly, any particles that interact via valence-limited ligand-receptor binding. Our theory correctly incorporates the…

Soft Condensed Matter · Physics 2015-06-05 Patrick Varilly , Stefano Angioletti-Uberti , Bortolo M. Mognetti , Daan Frenkel

We demonstrate that the experimental results reported by M. Shuker, O. Firstenberg, R. Pugatch, A. Ben-Kish,1 A. Ron, and N. Davidson, Phys. Rev. A {\bf 76}, 023813 (2007) as Dicke narrowing of electromagnetically induced transparency, does…

Optics · Physics 2007-11-14 S. M. Iftiquar