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We study theoretically the capturing of paramagnetic beads by a magnetic field gradient in a microfluidic channel treating the beads as a continuum. Bead motion is affected by both fluidic and magnetic forces. The transfer of momentum from…

Fluid Dynamics · Physics 2009-01-20 Christian Mikkelsen , Henrik Bruus

We propose a coarse-grained theoretical model to capture the aging of microfluidic devices under different conditions including constant applied flow rate and constant applied pressure gradient. Microfluidic devices that sort cells by their…

Soft Condensed Matter · Physics 2022-05-19 Gess Kelly , Thomas G. Fai

The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red…

Fluid Dynamics · Physics 2008-10-14 Amir H. G. Isfahani , Hong Zhao , Jonathan B. Freund

A flux-splitting method is proposed for the hyperbolic-equation system (HES) of magnetized electron fluids in quasi-neutral plasmas. The numerical fluxes are split into four categories, which are computed by using an upwind method which…

Computational Physics · Physics 2017-12-11 R. Kawashima , K. Komurasaki , T. Schoenherr

A two-dimensional flow in a 90 degree bent channel is considered. A magnetic field is uniform and parallel to inlet branch of the channel. A spectral/hp element method was used for liquid motion calculations. Three types of steady flows…

Fluid Dynamics · Physics 2018-08-29 Alexander V. Proskurin , Anatoly M. Sagalakov

Microfluidics offer remarkable flexibility for in-flow analyte characterization and can even measure the mechanical properties of biological cells through the application of hydrodynamic forces. In this work, we present a new approach to…

Soft Condensed Matter · Physics 2025-01-22 Alberto Martin-Perez , Daniel Ramos

Thrombosis is a common complication following the surgical implantation of blood contacting devices, and is strongly influenced by the phenomenon of near-wall enrichment of platelets. This paper describes a multi-constituent continuum…

Fluid Dynamics · Physics 2017-05-09 Wei-Tao Wu , Nadine Aubry , James F. Antaki , Mehrdad Massoudi

Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…

Fluid Dynamics · Physics 2025-08-04 Maxx Yung

An analytical analysis is presented of the transport and capture of magnetic micro/nano-particles in a magnetophoretic microsystem that consists of an array of integrated soft-magnetic elements embedded beneath a microfluidic channel. The…

Biological Physics · Physics 2009-11-13 E. P. Furlani

Strong control over experimental conditions in microfluidic channels provides a unique opportunity to study and optimize membraneless microbial fuel cells (MFCs), particularly with respect to the role of flow. However, improved performance…

Significant progress has been made to increase access to droplet microfluidics for labs with limited microfluidics expertise or fabrication equipment. In particular, using off-the-shelf systems has been a valuable approach. However, the…

We develop a mother machine-like microfluidic device specifically designed to track the proliferation of T-cells via live-cell microscopy. Although numerous microfluidic setups have been developed to study cell proliferation at the…

Cell Behavior · Quantitative Biology 2025-09-09 Simone Scalise , Giovanna Peruzzi , Davide Caprini , Giorgio Gosti , Giancarlo Ruocco , Mattia Miotto

Blood flowing through microvascular bifurcations has been an active research topic for many decades, while the partitioning pattern of nanoscale solutes in the blood remains relatively unexplored. Here, we demonstrate a multiscale…

The evaporation of drops of water placed at the center of long poly(methyl methacrylate) microfluidic channels with a rectangular cross section of 0.38 mm2 is studied by simultaneously monitoring the shapes of two samples, one is in a 300…

Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…

A numerical model is developed for the motion of superparamagnetic nanoparticles in a non-Newtonian blood flow under the influence of a magnetic field. The rheological properties of blood are modeled by the Carreau flow and viscosity, and…

Biological Physics · Physics 2022-07-14 M. Lee , A. Shelke , S. Singh , J. Fan , P. Zaleski , S. Afkhami

We investigate the effect of particle volume fraction on the efficiency of deterministic lateral displacement (DLD) devices. DLD is a popular passive sorting technique for microfluidic applications. Yet, it has been designed for treating…

Soft Condensed Matter · Physics 2015-10-27 Rohan Vernekar , Timm Krüger

Evaporation of blood droplets and diluted blood samples is a topic of intensive research, as it is seen as a possible low-cost tool for diagnosis. So far, samples with volume fraction down to a few percents of Red Blood Cells (RBCs) have…

The distribution of Red Blood Cells in a confined channel flow is inhomogeneous and shows a marked depletion near the walls due to a competition between migration away from the walls and shear-induced diffusion resulting from interactions…

Biological Physics · Physics 2015-06-15 Xavier Grandchamp , Gwennou Coupier , Aparna Srivastav , Christophe Minetti , Thomas Podgorski

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture