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Spiking activity of neurons engaged in learning and performing a task show complex spatiotemporal dynamics. While the output of recurrent network models can learn to perform various tasks, the possible range of recurrent dynamics that…

Neurons and Cognition · Quantitative Biology 2018-08-21 Christopher Kim , Carson Chow

Network control theory (NCT) has recently been utilized in neuroscience to facilitate our understanding of brain stimulation effects. A particularly useful branch of NCT is optimal control, which focuses on applying theoretical and…

Other Quantitative Biology · Quantitative Biology 2025-01-17 Kangli Dong , Siya Chen , Ying Dan , Lu Zhang , Xinyi Li , Wei Liang , Yue Zhao , Yu Sun

Despite considerable theoretical progress in the training of neural networks viewed as a multi-agent system of neurons, particularly concerning biological plausibility and decentralized training, their applicability to real-world problems…

Neural and Evolutionary Computing · Computer Science 2023-10-17 Arshia Soltani Moakhar , Mohammad Azizmalayeri , Hossein Mirzaei , Mohammad Taghi Manzuri , Mohammad Hossein Rohban

We consider a simple neural field model in which the state variable is dendritic voltage, and in which somas form a continuous one-dimensional layer. This neural field model with dendritic processing is formulated as an integro-differential…

Dynamical Systems · Mathematics 2020-03-31 Daniele Avitabile , Stephen Coombes , Pedro M. Lima

Tensor parallelism is an essential technique for distributed training of large neural networks. However, automatically determining an optimal tensor parallel strategy is challenging due to the gigantic search space, which grows…

Machine Learning · Computer Science 2025-08-06 Ziji Shi , Le Jiang , Ang Wang , Jie Zhang , Chencan Wu , Yong Li , Xiaokui Xiao , Wei Lin , Jialin Li

Combinatorial optimization problems are typically tackled by the branch-and-bound paradigm. We propose a new graph convolutional neural network model for learning branch-and-bound variable selection policies, which leverages the natural…

Machine Learning · Computer Science 2019-10-31 Maxime Gasse , Didier Chételat , Nicola Ferroni , Laurent Charlin , Andrea Lodi

Deep neural networks and brains both learn and share superficial similarities: processing nodes are likened to neurons and adjustable weights are likened to modifiable synapses. But can a unified theoretical framework be found to underlie…

Disordered Systems and Neural Networks · Physics 2025-09-29 Arsham Ghavasieh , Meritxell Vila-Minana , Akanksha Khurd , John Beggs , Gerardo Ortiz , Santo Fortunato

Maximum entropy methods provide a principled path connecting measurements of neural activity directly to statistical physics models, and this approach has been successful for populations of $N\sim 100$ neurons. As $N$ increases in new…

Biological Physics · Physics 2023-10-18 Christopher W. Lynn , Qiwei Yu , Rich Pang , William Bialek , Stephanie E. Palmer

The task of learning a diffusion-based neural sampler for drawing samples from an unnormalized target distribution can be viewed as a stochastic optimal control problem on path measures. However, the training of neural samplers can be…

Machine Learning · Computer Science 2026-05-20 Wei Guo , Jaemoo Choi , Yuchen Zhu , Molei Tao , Yongxin Chen

A dynamical neural network consists of a set of interconnected neurons that interact over time continuously. It can exhibit computational properties in the sense that the dynamical system's evolution and/or limit points in the associated…

Machine Learning · Computer Science 2018-05-24 Tsung-Han Lin , Ping Tak Peter Tang

This paper presents a novel, mathematically rigorous framework for autoencoder-type deep neural networks that combines optimal control theory and low-rank tensor methods to yield memory-efficient training and automated architecture…

Optimization and Control · Mathematics 2025-09-11 Ratna Khatri , Anthony Kolshorn , Colin Olson , Harbir Antil

Cortical network functioning critically depends on finely tuned interactions to afford neuronal activity propagation over long distances while avoiding runaway excitation. This importance is highlighted by the pathological consequences and…

Neurons and Cognition · Quantitative Biology 2022-10-12 Christian Meisel

The performance of a deep neural network is heavily dependent on its architecture and various neural architecture search strategies have been developed for automated network architecture design. Recently, evolutionary neural architecture…

Neural and Evolutionary Computing · Computer Science 2020-03-27 Haoyu Zhang , Yaochu Jin , Ran Cheng , Kuangrong Hao

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

The availability of large-scale neuronal population datasets necessitates new methods to model population dynamics and extract interpretable, scientifically translatable insights. Existing deep learning methods often overlook the biological…

Neurons and Cognition · Quantitative Biology 2024-11-14 Parsa Delavari , Ipek Oruc , Timothy H Murphy

Much of the information processing performed by a neuron occurs in the dendritic tree. For neural systems using light for communication, it is advantageous to convert signals to the electronic domain at synaptic terminals so dendritic…

Neural and Evolutionary Computing · Computer Science 2019-04-08 Jeffrey M. Shainline

How neurons integrate the myriad synaptic inputs scattered across their dendrites is a fundamental question in neuroscience. Multiple neurophysiological experiments have shown that dendritic non-linearities can have a strong influence on…

Neurons and Cognition · Quantitative Biology 2025-01-13 Clarissa Lauditi , Enrico M. Malatesta , Fabrizio Pittorino , Carlo Baldassi , Nicolas Brunel , Riccardo Zecchina

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

Neurons and Cognition · Quantitative Biology 2016-11-28 Rahul Badhwar , Ganesh Bagler

Suppose a target is hidden in one of the vertices of an edge-weighted graph according to a known probability distribution. The expanding search problem asks for a search sequence of the vertices so as to minimize the expected time for…

Discrete Mathematics · Computer Science 2019-11-21 Ben Hermans , Roel Leus , Jannik Matuschke

Cue integration, the combination of different sources of information to reduce uncertainty, is a fundamental computational principle of brain function. Starting from a normative model we show that the dynamics of multi-compartment neurons…

Neurons and Cognition · Quantitative Biology 2020-06-29 Jakob Jordan , João Sacramento , Mihai A. Petrovici , Walter Senn