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If we are ever to unravel the mysteries of brain function at its most fundamental level, we will need a precise understanding of how its component neurons connect to each other. Electron Microscopes (EM) can now provide the nanometer…

Computer Vision and Pattern Recognition · Computer Science 2016-09-28 Pascal Fua , Graham Knott

Neuronal circuits internally regulate electrical signaling via a host of homeostatic mechanisms. Two prominent mechanisms, synaptic scaling and structural plasticity, are believed to maintain average activity within an operating range by…

Neurons and Cognition · Quantitative Biology 2021-04-07 Saeed Aljaberi , Timothy O'Leary , Fulvio Forni

Multiplex networks allow us to study a variety of complex systems where nodes connect to each other in multiple ways, for example friend, family, and co-worker relations in social networks. Link prediction is the branch of network analysis…

Social and Information Networks · Computer Science 2022-11-23 Michele Coscia , Christian Borgelt , Michael Szell

Actin cytoskeletal protrusions in crawling cells, or lamellipodia, exhibit various morphological properties such as two characteristic peaks in the distribution of filament orientation with respect to the leading edge. To understand these…

Subcellular Processes · Quantitative Biology 2011-02-23 D. A. Quint , J. M. Schwarz

Understanding how recurrent neural circuits can learn to implement dynamical systems is a fundamental challenge in neuroscience. The credit assignment problem, i.e. determining the local contribution of each synapse to the network's global…

Neurons and Cognition · Quantitative Biology 2017-08-08 Alireza Alemi , Christian Machens , Sophie Denève , Jean-Jacques Slotine

We consider a growing planar network where a tip grows at constant speed, branches at constant rate and inactivates when it meets a branch already created. We only consider here orthogonal branching occurring always in the same direction.…

Probability · Mathematics 2026-04-22 Vincent Bansaye , Gael Raoul , Milica Tomasevic

The angular synchronization problem aims to accurately estimate (up to a constant additive phase) a set of unknown angles $\theta_1, \dots, \theta_n\in[0, 2\pi)$ from $m$ noisy measurements of their offsets $\theta_i-\theta_j \;\mbox{mod}…

Machine Learning · Computer Science 2024-02-13 Yixuan He , Gesine Reinert , David Wipf , Mihai Cucuringu

Building on evidence of structural parallels between brain networks and the cosmic web [1], we apply AI-based geometric analysis to cultured neuronal networks. Isolated neurons self-organize into dendritic lattices shaped by reproducible…

Neurons and Cognition · Quantitative Biology 2025-10-14 Wolfgang Kurz , Danny Baranes

Artificial Intelligence has looked into biological systems as a source of inspiration. Although there are many aspects of the brain yet to be discovered, neuroscience has found evidence that the connections between neurons continuously grow…

Neural and Evolutionary Computing · Computer Science 2020-10-29 Javier Lopez Randulfe , Leon Bonde Larsen

During development, the mammalian brain differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of…

Neurons and Cognition · Quantitative Biology 2010-04-14 Michael I. Ham , Vadas Gintautas , Marko A. Rodriguez , Ryan A. Bennett , Cara L. Santa Maria , Luis M. A. Bettencourt

Grid cells in the brain respond when an animal occupies a periodic lattice of "grid fields" during spatial navigation. The grid scale varies along the dorso-ventral axis of the entorhinal cortex. We propose that the grid system minimizes…

Neurons and Cognition · Quantitative Biology 2018-05-14 Xue-Xin Wei , Jason Prentice , Vijay Balasubramanian

To understand biological intelligence we need to map neuronal networks in vertebrate brains. Mapping mesoscale neural circuitry is done using injections of tracers that label groups of neurons whose axons project to different brain regions.…

Neurons and Cognition · Quantitative Biology 2025-05-13 Samik Banerjee , Caleb Stam , Daniel J. Tward , Steven Savoia , Yusu Wang , Partha P. Mitra

On a variety of tasks, the performance of neural networks predictably improves with training time, dataset size and model size across many orders of magnitude. This phenomenon is known as a neural scaling law. Of fundamental importance is…

Machine Learning · Statistics 2024-06-25 Blake Bordelon , Alexander Atanasov , Cengiz Pehlevan

We study a mathematical model of biological neuronal networks composed by any finite number $N \geq 2$ of non necessarily identical cells. The model is a deterministic dynamical system governed by finite-dimensional impulsive differential…

Biological Physics · Physics 2013-11-19 Eleonora Catsigeras

The information of spiking neural networks (SNNs) are propagated between the adjacent biological neuron by spikes, which provides a computing paradigm with the promise of simulating the human brain. Recent studies have found that the time…

Neural and Evolutionary Computing · Computer Science 2022-05-05 Pengfei Sun , Longwei Zhu , Dick Botteldooren

Several recently proposed architectures of neural networks such as ResNeXt, Inception, Xception, SqueezeNet and Wide ResNet are based on the designing idea of having multiple branches and have demonstrated improved performance in many…

Machine Learning · Computer Science 2018-08-26 Hongyang Zhang , Junru Shao , Ruslan Salakhutdinov

Neural Networks and Decision Trees: two popular techniques for supervised learning that are seemingly disconnected in their formulation and optimization method, have recently been combined in a single construct. The connection pivots on…

Machine Learning · Statistics 2020-02-27 Giuseppe Nuti , Lluís Antoni Jiménez Rugama , Kaspar Thommen

Learning and decision making in the brain are key processes critical to survival, and yet are processes implemented by non-ideal biological building blocks which can impose significant error. We explore quantitatively how the brain might…

Neurons and Cognition · Quantitative Biology 2011-04-19 Jake Bouvrie , Jean-Jacques Slotine

We present a mathematical analysis of a networks with Integrate-and-Fire neurons and adaptive conductances. Taking into account the realistic fact that the spike time is only known within some \textit{finite} precision, we propose a model…

Biological Physics · Physics 2010-11-09 B. Cessac , T. Vieville

Recent advances in neuroscience have revealed many principles about neural processing. In particular, many biological systems were found to reconfigure/recruit single neurons to generate multiple kinds of decisions. Such findings have the…

Machine Learning · Computer Science 2019-05-30 Yassin Khalifa , Justin Hawks , Ervin Sejdic
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