Related papers: A novel canard-based mechanism for mixed-mode osci…
Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…
In this paper, we consider a mass-spring-friction oscillator with the friction modelled by a regularized stiction model in the limit where the ratio of the natural spring frequency and the forcing frequency is on the same order of magnitude…
Biological neural networks face a formidable task: performing reliable computations in the face of intrinsic stochasticity in individual neurons, imprecisely specified synaptic connectivity, and nonnegligible delays in synaptic…
Pulse-coupled systems such as spiking neural networks exhibit nontrivial invariant sets in the form of attracting yet unstable saddle periodic orbits where units are synchronized into groups. Heteroclinic connections between such orbits may…
The pedunculopontine nucleus (PPN) is a heterogeneous brainstem locomotor hub implicated in Parkinson's disease and potentially relevant for its treatment. We propose single-compartment, conductance-based models for three classes of PPN…
Synaptic noise plays a major role in setting up coexistence of various firing patterns, but the precise mechanisms whereby these synaptic noise contributes to coexisting firing activities are subtle and remain elusive. To investigate these…
Neural dynamics is determined by the transmission of discrete synaptic pulses (synaptic shot-noise) among neurons. However, the neural responses are usually obtained within the diffusion approximation modeling synaptic inputs as continuous…
Variability in neural responses is an ubiquitous phenomenon in neurons, usually modeled with stochastic differential equations. In particular, stochastic integrate-and-fire models are widely used to simplify theoretical studies. The…
Biochemical circadian rhythm oscillations play an important role in many signalling mechanisms. In this work, we explore some of the biophysical mechanisms responsible for sustaining robust oscillations by constructing a minimal but…
In this paper, we investigate the fundamental limits on how the inter- spike time of a neuron oscillator can be perturbed by the application of a bounded external control input (a current stimulus) with zero net electric charge…
A detailed study of the slow manifold of a model exhibiting mixed-mode oscillations is presented. A scenario for the emergence of mixed-mode states which does not involve phase locking on a 2-torus is constructed. We show that mixed-modes…
Recent advances in sleep neurobiology have allowed development of physiologically based mathematical models of sleep regulation that account for the neuronal dynamics responsible for the regulation of sleep-wake cycles and allow detailed…
The mechanisms and impact of correlated, or synchronous, firing among pairs and groups of neurons is under intense investigation throughout the nervous system. A ubiquitous circuit feature that can give rise to such correlations consists of…
We study a family of non-linear McKean-Vlasov SDEs driven by a Poisson measure, modelling the mean-field asymptotic of a network of generalized Integrate-and-Fire neurons. We give sufficient conditions to have periodic solutions through a…
The presence of correlated noise, arising from a mixture of independent fluctuations and a common noisy input shared across the neural population, is a ubiquitous feature of neural circuits, yet its impact on collective network dynamics…
We propose a biologically inspired model of spiking neurons based on the dynamics of a damped, driven pendulum. Unlike traditional models such as the Leaky Integrate-and-Fire (LIF) neurons, the pendulum neuron incorporates second-order,…
In this work we consider two-dimensional critical manifolds in planar fast-slow systems near fold and so-called canard (=`duck') points. These higher-dimension, and lower-codimension, situation is directly motivated by the case of…
Neuronal voltage dynamics of regularly firing neurons typically has one stable attractor: either a fixed point (like in the subthreshold regime) or a limit cycle that defines the tonic firing of action potentials (in the suprathreshold…
We study a stochastic process describing the continuous time evolution of the membrane potentials of finite system of neurons in the absence of external stimuli. The values of the membrane potentials evolve under the effect of {\it chemical…
We study the dynamics of a simple adaptive system in the presence of noise and periodic damping. The system is composed by two paths connecting a source and a sink, the dynamics is governed by equations that usually describe food search of…