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Medical digital twins are computational models of human biology relevant to a given medical condition, which can be tailored to an individual patient, thereby predicting the course of disease and individualized treatments, an important goal…

As introduced by Bentley et al. (2005), artificial immune systems (AIS) are lacking tissue, which is present in one form or another in all living multi-cellular organisms. Some have argued that this concept in the context of AIS brings…

Artificial Intelligence · Computer Science 2010-07-05 Jan Feyereisl , Uwe Aickelin

The pursuit of creating artificial intelligence (AI) mirrors our longstanding fascination with understanding our own intelligence. From the myths of Talos to Aristotelian logic and Heron's inventions, we have sought to replicate the marvels…

Neurons and Cognition · Quantitative Biology 2024-11-26 Nima Dehghani , Michael Levin

The role of T-cells within the immune system is to confirm and assess anomalous situations and then either respond to or tolerate the source of the effect. To illustrate how these mechanisms can be harnessed to solve real-world problems, we…

Artificial Intelligence · Computer Science 2010-07-05 Jungwon Kim , William Wilson , Uwe Aickelin , Julie McLeod

A model of an organism as an autonomous intelligent system has been proposed. This model was used to analyze learning of an organism in various environmental conditions. Processes of learning were divided into two types: strong and weak…

Artificial Intelligence · Computer Science 2007-05-23 Alexey V. Melkikh

In this little vision paper we analyze the human immune system from a computer science point of view with the aim of understanding the architecture and features that allow robust, effective behavior to emerge from local sensing and actions.…

Computational Engineering, Finance, and Science · Computer Science 2013-09-23 Carolyn Talcott

The Attacks done by Viruses, Worms, Hackers, etc. are a Network Security-Problem in many Organisations. Current Intrusion Detection Systems have significant Disadvantages, e.g. the need of plenty of Computational Power or the Local…

Cryptography and Security · Computer Science 2008-05-08 Michael Hilker , Christoph Schommer

The similarity between neural and immune networks has been known for decades, but so far we did not understand the mechanism that allows the immune system, unlike associative neural networks, to recall and execute a large number of…

Disordered Systems and Neural Networks · Physics 2017-03-20 Elena Agliari , Alessia Annibale , Adriano Barra , A. C. C. Coolen , Daniele Tantari

Systems Biology has emerged in the last years as a new holistic approach based on the global understanding of cells instead of only being focused on their individual parts (genes or proteins), to better understand the complexity of human…

We explore the commonalities between methods for assuring the security of computer systems (cybersecurity) and the mechanisms that have evolved through natural selection to protect vertebrates against pathogens, and how insights derived…

It is proposed that using both self-non-self and danger theories give a better understanding of how the immune system works. It is proposed that comparing immune system to police force is useful in this case since police responds both to…

Populations and Evolution · Quantitative Biology 2008-01-08 E. Ahmed , A. H. Hashish

By developing communications and increase of access points, computer networks have been vulnerable considerably against wide range of information attacks, specially new and complicated attacks. Every day, replication attacks attack millions…

Cryptography and Security · Computer Science 2015-04-15 Amir Hosein Bodaghi

The immune system is a real-time example of an evolving system that navigates the essentially infinite complexity of protein sequence space. How this system responds to disease and vaccination is discussed. Of particular focus is the case…

Cell Behavior · Quantitative Biology 2007-05-23 Michael W. Deem

Organisms have evolved immune systems that can counter pathogenic threats. The adaptive immune system in vertebrates consists of a diverse repertoire of immune receptors that can dynamically reorganize to specifically target the…

Populations and Evolution · Quantitative Biology 2024-10-29 Quinn N Bellamy , Zachary Montague , Luca Peliti , Armita Nourmohammad

The detection of anomalies in unknown environments is a problem that has been approached from different perspectives with variable results. Artificial Immune Systems (AIS) present particularly advantageous characteristics for the detection…

Cryptography and Security · Computer Science 2021-09-14 Pedro Pinacho-Davidson , Matías Lermanda , Ricardo Contreras , María A. Pinninghoff

Artificial Immune Systems have been used successfully to build recommender systems for film databases. In this research, an attempt is made to extend this idea to web site recommendation. A collection of more than 1000 individuals web…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Tom Morrison , Uwe Aickelin

The analysis of system calls is one method employed by anomaly detection systems to recognise malicious code execution. Similarities can be drawn between this process and the behaviour of certain cells belonging to the human immune system,…

Artificial Intelligence · Computer Science 2010-07-05 Jungwon Kim , Julie Greensmith , Jamie Twycross , Uwe Aickelin

Almost every biological, economic and social system is a complex adaptive system (CAS). Mathematical and computer models are relevant to CAS. Some approaches to modeling CAS are given. Applications in vaccination and the immune system are…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 E. Ahmed , A. S. Elgazzar , A. S. Hegazi

Adversarial attacks against deep neural networks are continuously evolving. Without effective defenses, they can lead to catastrophic failure. The long-standing and arguably most powerful natural defense system is the mammalian immune…

Machine Learning · Computer Science 2020-12-22 Ren Wang , Tianqi Chen , Stephen Lindsly , Alnawaz Rehemtulla , Alfred Hero , Indika Rajapakse

Intelligence can be defined as a predominantly human ability to accomplish tasks that are generally hard for computers and animals. Artificial Intelligence [AI] is a field attempting to accomplish such tasks with computers. AI is becoming…

Artificial Intelligence · Computer Science 2019-05-03 George Cevora