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Molecular motors are macromolecular complexes which use some form of input energy to perform mechanical work. The filamentary tracks, on which these motors move, are made of either proteins (e.g., microtubules) or nucleic acids (DNA or…

The transport approach is a useful tool to study dynamics of non-equilibrium systems. For heavy-ion collisions at intermediate energies, where both the smooth nucleon potential and the hard-core nucleon-nucleon collision are important, the…

Nuclear Theory · Physics 2019-04-02 Jun Xu

The ability of cells to move through small spaces depends on the mechanical properties of the cellular cytoskeleton and on nuclear deformability. In mammalian cells, the cytoskeleton is comprised of three interacting, semi-flexible polymer…

Biological Physics · Physics 2021-10-27 Sarthak Gupta , Alison E. Patteson , J. M. Schwarz

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

Mixtures of active and passive particles are ubiquitous at the microscale. Many essential microbial processes involve interactions with dead or immotile cells or passive crowders. When passive objects are immersed in active baths, their…

Soft Condensed Matter · Physics 2026-02-24 Horacio Serna , C. Miguel Barriuso G. , Ignacio Pagonabarraga , Marco Polin , Chantal Valeriani

Many natural and industrial processes rely on constrained transport, such as proteins moving through cells, particles confined in nanocomposite materials or gels, individuals in highly dense collec- tives and vehicular traffic conditions.…

Nucleation is often accompanied by heat transfer between the surroundings and a nucleus of a new phase. The interface between two phases gives an additional resistance to this transfer. For small nuclei the interfacial curvature is high,…

Soft Condensed Matter · Physics 2015-06-17 K. S. Glavatskiy , D. Bedeaux

Anomalous transport processes in which the variance of the distance travelled does not necessarily increase linearly with time are modelled using the formalism of continuous time random walks. We compute particle propagators which have the…

Astrophysics · Physics 2011-05-23 B. R. Ragot , J. G. Kirk

We present a general theoretical framework to discuss mechanisms of morphogen transport and gradient formation in a cell layer. Trafficking events on the cellular scale lead to transport on larger scales. We discuss in particular the case…

Other Quantitative Biology · Quantitative Biology 2015-06-26 T. Bollenbach , K. Kruse , P. Pantazis , M. Gonzalez-Gaitan , F. Julicher

Systems switching between different dynamical phases is an ubiquitous phenomenon. The general understanding of such a process is limited. To this end, we present a general expression that captures fluctuations of a system exhibiting a…

Statistical Mechanics · Physics 2024-12-05 Ion Santra , Kristian Stølevik Olsen , Deepak Gupta

The biotransport of the intravascular nanoparticle (NP) is influenced by both the complex cellular flow environment and the NP characteristics. Being able to computationally simulate such intricate transport phenomenon with high efficiency…

Fluid Dynamics · Physics 2018-04-24 Zixiang Liu , Yuanzheng Zhu , Rekha R. Rao , Jonathan R. Clausen , Cyrus K. Aidun

We present here a detailed description of the model of ran-driven nuclear transduction in living cells to be published elswere. The mathematical model presented is the first to account for the active transport of molecules along the…

Numerical Analysis · Mathematics 2009-07-07 A. Cangiani

Active fluctuations are detected in a growing number of systems due to self-propulsion mechanisms or collisions with active environment. They drive the system far from equilibrium and can induce phenomena which at equilibrium states are…

Statistical Mechanics · Physics 2024-09-12 K. Białas , J. Łuczka , J. Spiechowicz

We develop an agent-based model of the motion and pattern formation of vesicles. These intracellular particles can be found in four different modes of (undirected and directed) motion and can fuse with other vesicles. While the size of…

Subcellular Processes · Quantitative Biology 2011-09-19 Mirko Birbaumer , Frank Schweitzer

A microscopic description of packet transport in the Internet by using a simple cellular automaton model is presented. A generalised exclusion process is introduced which allows to study travel times of the particles ('data packets') along…

The transport and chemical reactions of solutes are modelled as a cellular automaton in which molecules of different species perform a random walk on a regular lattice and react according to a local probabilistic rule. The model describes…

comp-gas · Physics 2009-10-22 T. Karapiperis , B. Blankleider

Nuclear pore complexes (NPCs) are very selective filters that monitor the transport between the cytoplasm and the nucleoplasm. Two models have been suggested for the plug of the NPC. They are (i) it is a reversible hydrogel or (ii) it is a…

Soft Condensed Matter · Physics 2014-06-25 Rajarshi Chakrabarti , Ananya Debnath , K. L. Sebastian

We consider an inhomogeneous strongly correlated system where external disorder divides it into mesoscopic cells.Strong inter-particle repulsion suppresses the quantum tunneling between cells and open a wide temperature range for incoherent…

Strongly Correlated Electrons · Physics 2007-05-23 Darwin Chang , Dung-Hai Lee

We propose a stochastic model for intracellular transport processes associated with the activity of molecular motors. This out-of-equilibrium model, based on a generalized Langevin equation, considers a particle immersed in a viscoelastic…

Biological Physics · Physics 2009-04-15 L. Bruno , M. A. Despósito

Molecular motors transport various cargos along cytoskeletal filaments, analogous to trucks on roads. In contrast to vehicles, however, molecular motors do not work alone but in small teams. We describe a simple model for the transport of a…

Statistical Mechanics · Physics 2008-07-08 Melanie J. I. Müller , Janina Beeg , Rumiana Dimova , Stefan Klumpp , Reinhard Lipowsky